Research Commercialization

Institutionally Coordinated - contact RDS if you are interested in this funding opportunity // Limit: 2 (lead organization)

SUBJECT TO CHANGE STATEMENT: The terms of this funding opportunity are actively under ORP review and the competition is thus subject to change. The solicitation indicates that academic institutions are not the end goal for this funding. 

Limiting Language 
An eligible organization can submit a maximum of two Written Proposals per Topic Announcement for Phase 0 as a lead organization. Senior/Key Personnel may be listed on a maximum of one Written Proposal per Topic Announcement.

Topic Description

Every revolution in science has been preceded by a revolution in what we can measure, from the telescope to modern Magnetic Resonance Imaging (MRI) machines. Today, the frontier is starved for radically new modalities for sensing and imaging. We cannot watch a non-crystalline enzyme work at atomic resolution, probe the full dynamics of a working synapse, or identify the most reactive surface defect structures on advanced catalytic materials.

NSF X-Labs in this Topic will target specific platform technologies in sensing, imaging and supporting technologies that will form the basis for revolutionary new capabilities in scientific discovery and technology sectors. Teams might, for example, draw on quantum sensing, artificial intelligence (AI)-driven computational imaging, adaptive AI-based sensing algorithms, and/or entirely new modalities to redefine what we consider knowable. 

Examples of relevant, currently unmet R&D challenges may include, but are not limited to: detection of molecular-scale single-reaction events across timescales of femtoseconds to seconds; MRI-free deep-tissue imaging; non-destructive biomolecule microscopy at exquisite resolution; high-sensitivity quantum sensors suitable for operation in a variety of environments; instruments intentionally engineered for next-generation AI training pipelines; and sensors to resolve whole-brain activity at cellular resolution across long timescales. 

An NSF X-Labs Mission in this Topic must be transformative, accelerating breakthrough R&D in scientific instrumentation towards creating or reshaping new lines of research and technologies. Successful teams will overcome technical barriers facing sensing and imaging, develop platform technologies, demonstrate measurable impact on the U.S. science and technology landscape, and position their technologies for widespread use and investment in research and/or other sectors. 

Examples of challenges not considered in scope for this Topic include computational or software solutions without practical integration into an instrumentation system, development of technologies where the impact is narrow and not widely deployable, fundamental research without potential for application in platform technologies, incremental advancement of the state of the art, or advancement of technologies that are already appropriately developed to the point of full-scale commercialization.

Full sponsor guidelines are linked here. 

Upcoming Webinars
Thursday, May 28, 1–2 p.m. Eastern Daylight Time (EDT) 
Introduction to NSF X-Labs Funding Opportunity – Scientific Instrumentation for Sensing and Imaging
Register for the May 28 webinar.

Tuesday June 23, 2:30–3:30 p.m. EDT
Q&A for NSF X-Labs – Scientific Instrumentation for Sensing and Imaging
Register for the June 23 Q&A session.

Institutionally Coordinated - contact RDS if you are interested in this funding opportunity // Limit: 2 (lead organization)

SUBJECT TO CHANGE STATEMENT: The terms of this funding opportunity are actively under ORP review and the competition is thus subject to change. The solicitation indicates that academic institutions are not the end goal for this funding. 

Limiting Language 
An eligible organization can submit a maximum of two Written Proposals per Topic Announcement for Phase 0 as a lead organization. Senior/Key Personnel may be listed on a maximum of one Written Proposal per Topic Announcement.

Topic Description
Quantum computing and quantum information processing systems sit at the cusp of a watershed moment: through years of federally funded foundational discovery in quantum phenomena coupled with more recent industry investment in the buildout of quantum components and systems, the world is about to witness a new era in modern computation. Future quantum computing is expected to rapidly accelerate scientific discovery and use-driven applications in a range of technology sectors, while unlocking entirely new frontiers beyond the reach of classical computing. But to realize future functional and connected quantum systems will require further investment in foundational platform technologies centered on quantum interconnects and integrated quantum photonics, which will be key enablers to combine different quantum capabilities into a single system. 

Future quantum systems are expected to rely on interconnects to transfer quantum information – coherence and entanglement – between discrete physical subsystems. Quantum photonic technologies that utilize photons as robust carriers of quantum information in distributed architectures offer a compelling pathway toward scalable quantum computing, sensing and metrology, and networking. Integrated quantum photonics will further extend this capacity by enabling dense integration of optical components (e.g., entangled sources, interferometers, filters, switches, and detectors) onto compact chips and packages. 

NSF X-Labs in this Topic will focus on the research and development of technologies to enable next-generation quantum interconnects, integrated quantum photonics and/or their supporting technologies. NSF X-Labs teams will target specific platform technologies that, if successful, will provide a roadmap for the integration of second-generation quantum systems. Examples of relevant, currently unmet R&D challenges may include, but are not limited to: scalable modular architectures based on the interconnection of discrete processing units; interconnection of heterogeneous quantum sub-systems via quantum transducers; reconfigurable quantum photonic circuits for compact multi-qubit operations; and next-generation quantum light sources, low-loss waveguides, and integrated single-photon detectors. NSF X-Labs in this Topic will aim to develop foundational platform solutions that can form the basis for broad industry adoption and integrated, system-level capabilities. 

An NSF X-Labs Mission in this Topic must be transformative, accelerating breakthrough R&D in quantum technologies towards creating or reshaping new lines of research and technologies. Successful teams will develop platform technologies, overcome technical barriers facing quantum systems, demonstrate measurable impact on the U.S. science and technology landscape, and position their technologies for widespread use and investment. 

Examples of challenges not considered in scope for this Topic include computational or software solutions without practical integration into a quantum system, solutions that are inherently unsuitable for future scaling and commercial adoption, development of technologies where the impact is narrow and not widely deployable, fundamental research without potential for application in platform technologies, incremental advancement of the state-of-the-art, or advancement of technologies that are already appropriately developed to the point of full-scale commercialization.

Full sponsor guidelines are linked here. 

Upcoming Webinars 

Thursday, June 4, 2–3 p.m. EDT
Introduction to NSF X-Labs Funding Opportunity - Quantum Systems: Interconnects and Integrated Photonics
Register for the June 4 webinar.

Tuesday, June 30, 2–3 p.m. EDT
Q&A for NSF X-Labs - Quantum Systems: Interconnects and Integrated Photonics 
Register for the June 30 Q&A session.

No Applicants 

The new VentureWell fellowship is an evolution of our C&P Grants model, focusing on scalable STEM I&E solutions through the lens of environmental sustainability and inclusive innovation. This program offers professional development, immersive learning experiences, and a supportive community of leaders.

VentureWell is replacing a three-year, $30,000 program with two opportunities: the new one-year fellowship and a two-year challenge grant, totaling up to $135,000 over three years.

• Develop courses, policies, and co-curricular programs to promote research and development (R&D) translation focused around environmental sustainability and inclusive innovation.
• Receive $35,000 in funding for teams of two (one must be faculty) from U.S.-based colleges and universities.
• Create a STEM I&E ecosystem growth plan to scale interventions in partnership with university leadership and external partners.

No Applicants  // Limit: 1 // Tickets Available: 1 

An Applicant may submit only one proposal in response to this Announcement. 

The mission of SBA’s Small Business Innovation Research and Technology Transfer Office (SBIRTT), which bears responsibility for administering the FAST program, is to strengthen the technological competitiveness of small businesses across the country through coordination and oversight of the Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs. The primary mission of the FAST program is to help underrepresented entrepreneurs successfully compete for SBIR/STTR awards.

The FAST program provides one-year funding to organizations to execute state-based programs, which may also collaborate regionally, that increase the number of SBIR/STTR proposals leading to an increase in the number of SBIR/STTR awards from women, socially/economically disadvantaged individuals, and small businesses in underrepresented areas - typically rural states.

No Applicants  // Limit: 1 // Tickets Available: 1 

Eligible organizations and institutions of higher learning may submit one (1) proposal in response to the Funding Opportunity. 

The purpose of this Funding Opportunity is to invite proposals for funding from eligible non-profit organizations, local and state government agencies, private sector firms, and institutions of higher education to provide quality training and counseling to veteran small business owners and entrepreneurs. A key component of this Funding Opportunity is for applicants to provide training to transitioning military personnel and spouses through the Boots to Business (B2B) Training Program, and to veterans and military spouses through the Reboot and Military Spouse Pathway to Business Training Programs.

Institutionally Coordinated //  Limit: 4* // Tickets Available: 3

J. Ruiz (Biosphere 2)
V. Subbian (Biomedical Engineering), sub to Univ. of Illinois Chicago (UIC).

*Please note that due to the size and complexity of the application process, the University of Arizona will institutionally coordinate no more than four (4) applications to this opportunity.

MacArthur today announced the launch of a new round of its 100&Change competition for a single $100 million grant to help solve one of the world's most critical social challenges. The third round of 100&Change remains open to organizations and collaborations working in any field, anywhere in the world. Proposals must identify a problem and offer a solution that promises significant and durable change; applications will be accepted online only, from May 22 to August 15, 2024. 

For the third round of the competition, MacArthur is adding “just” as a criterion to align with the Foundation’s Just Imperative, incorporating a sharper focus on how projects advance diversity, equity, and inclusion. No topic is exempt or excluded from these commitments.

100&Change remains global and athematic. The competition is unique because no field or problem area is designated, unlike most prizes and challenges, and proposals from all sectors and anywhere in the world are encouraged. To date, 100&Change has leveraged an additional $511 million in funding, spurring the philanthropic sector to rethink its approach to achieving impact at scale.

Preparation and Proposals

100&Change seeks proposals that articulate both a problem and its solution. Competitive proposals will address a significant problem and provide a solution that is impactful, evidence-based, feasible, durable, and just.

An organizational readiness tool is available to help organizations determine whether they are ready to compete in 100&Change. This tool was designed to help potential applicants understand characteristics of the most competitive organizations and proposals, and to determine how well-suited they are for 100&Change.

Limit: 1 // Tickets Available: 1 

*UA may submit one proposal under the Research Partnerships track. There is no institutional limitation on the Technology Translation track.

If you don’t have a demonstrated and substantial industry relationship as required for a PFI submission, please reach out to Brian Adair(link sends e-mail) or Lindsay Ridpath(link sends e-mail), to help develop those connections so that your proposal is competitive. PFI proposals are accepted three times per year and you may be better served by strengthening your industry relationship and waiting for the next cycle.


The Partnerships for Innovation (PFI) Program within the Division of Translational Impacts (TI) offers researchers from all disciplines of science and engineering funded by NSF the opportunity to perform translational research and technology development, catalyze partnerships and accelerate the transition of discoveries from the laboratory to the marketplace for societal benefit.

The Research Partnerships (PFI-RP) track seeks to achieve the same goals as the PFI-TT track by supporting instead complex, multi-faceted technology development projects that are typically beyond the scope of a single researcher or institution and require a multi-organizational, interdisciplinary, synergistic collaboration. A PFI-RP project requires the creation of partnerships between academic researchers and third-party organizations such as industry, non-academic research organizations, federal laboratories, public or non-profit technology transfer organizations or other universities. Such partnerships are needed to conduct use-inspired research on a stand-alone larger project toward commercialization and societal impact. In the absence of such synergistic partnership, the project’s likelihood for success would be minimal.

The intended outcomes of both PFI-TT and PFI-RP tracks are: a) the commercialization of new intellectual property derived from NSF-funded research outputs; b) the creation of new or broader collaborations with industry (including increased corporate sponsored research); c) the licensing of NSF-funded research outputs to third party corporations or to start-up companies funded by a PFI team; and d) the training of future innovation and entrepreneurship leaders.


 

The please be aware of important revisions in the PFI program recently announced in solicitation NSF 23-538, as outlined below:

NSF Lineage Requirement
Innovation Corps (NSF I-CorpsTM) Teams awards no longer convey the lineage required to submit a PFI proposal.
All proposals submitted to the PFI program must meet a lineage requirement by having NSF-supported research results in any field of science and engineering: Principal Investigator (PI) or a co-PI must have had an NSF award that ended no more than seven (7) years prior to the full proposal deadline date or be a current NSF award recipient. The proposed technology development project must be derived from the research results and/or discoveries from this underlying NSF award.

Award Information
The funding amounts in both tracks of the PFI program have significantly increased. Specifically:

• PFI-Technology Translation (PFI-TT) projects will be funded for up to $550,000 for 18-24 months per award; and
• PFI-Research Partnerships (PFI-RP) projects will be funded for up to $1,000,000 for 36 months.
   

New full proposal deadlines
The PFI solicitation has three revised deadlines each year:

• May 2, 2023
  First Tuesday in May, Annually Thereafter
• September 5, 2023
  First Tuesday in September, Annually Thereafter
• January 4, 2025
  First Tuesday in January, Annually Thereafter

Limit: 1// R. Liang (Wyant College of Optical Sciences)

*UA may submit one proposal under the Research Partnerships track. There is no institutional limitation on the Technology Translation track.

If you don’t have a demonstrated and substantial industry relationship as required for a PFI submission, please reach out to Brian Adair(link sends e-mail) or Lindsay Ridpath(link sends e-mail), to help develop those connections so that your proposal is competitive. PFI proposals are accepted three times per year and you may be better served by strengthening your industry relationship and waiting for the next cycle.


The Partnerships for Innovation (PFI) Program within the Division of Translational Impacts (TI) offers researchers from all disciplines of science and engineering funded by NSF the opportunity to perform translational research and technology development, catalyze partnerships and accelerate the transition of discoveries from the laboratory to the marketplace for societal benefit.

The Research Partnerships (PFI-RP) track seeks to achieve the same goals as the PFI-TT track by supporting instead complex, multi-faceted technology development projects that are typically beyond the scope of a single researcher or institution and require a multi-organizational, interdisciplinary, synergistic collaboration. A PFI-RP project requires the creation of partnerships between academic researchers and third-party organizations such as industry, non-academic research organizations, federal laboratories, public or non-profit technology transfer organizations or other universities. Such partnerships are needed to conduct use-inspired research on a stand-alone larger project toward commercialization and societal impact. In the absence of such synergistic partnership, the project’s likelihood for success would be minimal.

The intended outcomes of both PFI-TT and PFI-RP tracks are: a) the commercialization of new intellectual property derived from NSF-funded research outputs; b) the creation of new or broader collaborations with industry (including increased corporate sponsored research); c) the licensing of NSF-funded research outputs to third party corporations or to start-up companies funded by a PFI team; and d) the training of future innovation and entrepreneurship leaders.


 

The please be aware of important revisions in the PFI program recently announced in solicitation NSF 23-538, as outlined below:

NSF Lineage Requirement
Innovation Corps (NSF I-CorpsTM) Teams awards no longer convey the lineage required to submit a PFI proposal.
All proposals submitted to the PFI program must meet a lineage requirement by having NSF-supported research results in any field of science and engineering: Principal Investigator (PI) or a co-PI must have had an NSF award that ended no more than seven (7) years prior to the full proposal deadline date or be a current NSF award recipient. The proposed technology development project must be derived from the research results and/or discoveries from this underlying NSF award.

Award Information
The funding amounts in both tracks of the PFI program have significantly increased. Specifically:

• PFI-Technology Translation (PFI-TT) projects will be funded for up to $550,000 for 18-24 months per award; and

• PFI-Research Partnerships (PFI-RP) projects will be funded for up to $1,000,000 for 36 months.
   

New full proposal deadlines
The PFI solicitation has three revised deadlines each year:

• May 2, 2023
  First Tuesday in May, Annually Thereafter

• September 3, 2024
  First Tuesday in September, Annually Thereafter

• January 2, 2025
  First Tuesday in January, Annually Thereafter

No Applicants  // Limit: 1 // Tickets Available: 1 

Limit on Number of Proposals per Organization: 1

The purpose of this solicitation is to broaden participation in innovation ecosystems that advance key technologies (e.g., advanced manufacturing, advanced wireless, artificial intelligence, biotechnology, quantum information science, semiconductors, novel materials, and microelectronics) by supporting capacity-building efforts at institutions of higher education (IHEs) interested in growing external partnerships. Creation of this program is motivated by the commitment of the National Science Foundation (NSF), including the newly established NSF Directorate for Technology, Innovation and Partnerships (TIP), to accelerate scientific and technological innovation nationwide and empower all Americans to participate in the U.S. research and innovation enterprise. Establishing more inclusive innovation ecosystems will require broad networks of partners working together in support of use-inspired research; the translation of such research to practice or commercial application; and the development of a skilled workforce. The NSF Regional Innovation Engines (NSF Engines) program, housed within the TIP Directorate, seeks to grow inclusive innovation ecosystems around the country. Growing such ecosystems will only be successful if all interested IHEs within a region are able to participate and contribute their unique set of skills and expertise. However, NSF appreciates many Minority-Serving Institutions (MSIs), Predominantly Undergraduate Institutions (PUIs), and two-year institutions lack the infrastructure and resources needed to grow external partnerships and effectively contribute to innovation ecosystems, and thus are currently unable to effectively engage with the NSF Engines program.

This solicitation aims to provide MSIs, PUIs, and two-year institutions with limited or no research capacity (see Section IV for details) with the support necessary to become equitable partners with teams competing under the current and subsequent NSF Engines program funding opportunities. Importantly, participation in this solicitation is not predicated on an existing partnership with organizations submitting an NSF Engines proposal. Rather, it is expected that the capacity-building efforts funded under this solicitation will provide significant innovation partnership opportunities irrespective of future participation in an NSF Engine.

Institutionally Coordinated // Limit: 1 // L. Folks (Semiconductor Strategy)

Please contact the Center for Semiconductor Manufacturing (CSM)  for more information. 

Eligible applicants can only submit one concept plan paper under this NOFO.

Program Priorities

“Advanced packaging” refers to many chips with diverse functions assembled tightly together on a substrate in two or three dimensions at extremely fine dimensions. This method achieves function, performance, and power savings far greater than can be achieved with conventionally packaged chips on a printed circuit board. Recent advances in artificial intelligence, for example, would not be possible without advanced packaging.

Advanced packaging can be a transformative capability that helps U.S. manufacturers compete globally, but there are many technological challenges to solve. The CHIPS Research and Development Office has established the CHIPS National Advanced Packaging Manufacturing Program to address these challenges, including:

• How do we design and assemble chips so tightly that they behave like a single traditional large chip, but with the production efficiency and cost savings of advanced packaging?

• How do we supply power to and dissipate heat from such tightly coupled assemblies?

• How do we test and repair such complex assemblies?

• How do we ensure their reliability since traditional methods of visual inspection cannot be performed on such small, tightly packaged dimensions?

The CHIPS NAPMP will enable the development of a robust domestic advanced packaging ecosystem by:

• Establishing an advanced packaging piloting facility (or facilities) that accelerates the transfer of innovations in packaging, equipment, and process development into manufacturing;

• Driving the development of digital tools to reduce the time and cost of advanced packaging engineering; and,

• Establishing and supporting partnerships among industry, academia and training entities, and government to contribute to an advanced packaging workforce.

The six priority research investment areas of the CHIPS NAPMP are:

• Materials and substrates

• Equipment, tools, and processes

• Power delivery and thermal management for advanced packaging assemblies

• Photonics and connectors that communicate with the outside world

• A chiplet ecosystem

• Co-design of multi-chiplet systems with automated tools