Biomedical, Clinical & Life Sciences

Apply to Internal Competition // Limit: 1 // Tickets Available: 1

Limiting Language 
Brain Research Foundation is pleased to invite your institution to nominate one senior faculty member to submit a Letter of Intent for the 2027 Scientific Innovations Award (SIA).

Objectives
The objective of the SIA is to support projects that may be too innovative and speculative for traditional funding sources but still have a high likelihood of producing important findings. It is expected that investigations supported by these grants will yield high impact findings and result in major grant applications and significant publications in high impact journals.  

Eligibility 
The nominated candidate must be a full-time associate professor or full professor at a US academic institution that was invited directly by BRF via email, working in the area of studies of brain function in health and disease. Current major NIH or other peer-reviewed funding is preferred but evidence of such funding in the past three years is essential. Studies should be related to either normal human brain development or specifically identified disease states. This includes molecular and clinical neuroscience as well as studies of neural, sensory, motor, cognitive, behavioral and emotional functioning in health and disease. The grant proposal must detail a new research project that is not funded by other sources. This grant is not to be used as bridge funding.

Investigators at institutions that are affiliated with a medical school or university are eligible to apply only through the institution where they hold a full-time faculty position. 

Scientists that have previously received a BRF Scientific Innovations Award may not receive the award for a second time until five years has elapsed since the beginning date of the prior award. Grant requirements from all previous awards must be met.  Only one PI may apply per application. (Applicant may include the name of a Co-PI within or from another institution, but no additional supporting materials for the Co-PI are required, including biosketch, current grants, abstracts, etc.)

Full sponsor guidelines are linked here.

Apply to Internal Competition // Limit: 2 // Tickets Available: 2

The University of Arizona Cancer Center (UACC) is coordinating this limited submission. For more information please contact: UACC-PreAward.

Limiting Language
The University of Arizona Comprehensive Cancer Center (UACCC) can nominate up to two proposals for the Phi Beta Psi Research Grant 2026.

Applicant Eligibility
Research applications must be focused on brain, breast, colorectal, endometrial, lung, ovarian, pancreatic, gastrointestinal tract or prostate cancer.

• Preference is given to young investigators with documented evidence of potential for conducting novel research of either basic or clinical aspects of cancer and cancer-related problems.
• Applications from established investigators exploring new and innovative areas of cancer research will be considered.
• Post-doctoral fellows are not eligible.
• Research assistant professors may be eligible.
• The gold standard is as follows: if the individual is eligible to submit an R01 from their institution as Principal Investigator then they are eligible to submit a Phi Beta Psi grant application.

Funding Information:

• The research grants are based on the amount of donations from each Chapter to our Nation Project, cancer research. The organization anticipates six awards this year
• There is no set amount for this award but awards have ranged from $50,000 - $100,000+ in past years. (In 2025, the national membership voted to give $572K to six grant recipients. Each doctor received more than $95K.)
• Salaries of the Principal Investigators may not be included in the budget.
• The grants are intended to cover the salaries of people in the lab (post-docs, technicians, and biostatistician), not the PI or other senior-level faculty.
• Please note that Phi Beta Psi Charity Trust is a non-profit organization, which does not allow overhead costs to be charged by the host institution.
   

Apply to Internal Competition // Limit: 1 // Tickets Available: 1

Limiting Language 
Each invited institution may submit a single application from a full-time faculty member. The candidate must be from the Colleges of Medicine (Tucson or Phoenix). 

Program Description

Full sponsor guidelines are linked here.

The Harold S. Geneen Charitable Trust Awards Program for Coronary Heart Disease Research supports research in the prevention of coronary heart disease or circulatory failure and improving care for patients with these medical conditions. The program focuses on basic and translational scientific research. Clinical studies are currently ineligible. 

In accordance with Mr. Geneen’s directives, the program seeks to establish “…a more direct and personalized relationship with grant recipients than is normally possible in dealing with the diffuse and bureaucratic administrations through which large organizations are managed…and to support smaller institutions rather than major universities or medical complexes which have a demonstrated capacity to raise funds from the public generally.” Thus, eligible institutions represent mid-size institutions conducting relevant and innovative cardiovascular research. 

Each invited institution may only submit one application to the program which meets the eligibility requirements for the 2026 Grant Cycle. Applicants must be full-time faculty at an invited non-profit academic, medical, non-governmental or research institutions. United States citizenship is not required. Junior faculty are encouraged to apply. 

The Co-Trustees of the Harold S. Geneen Charitable Trust (Funder) have retained Health Resources in Action (HRiA - Administrator) to manage the administrative aspects of the Harold S. Geneen Charitable Trust Awards Program for Coronary Heart Disease Research. Health Resources in Action (HRiA) is a non-profit organization that partners with individuals, organizations, and communities to transform the practices, policies, and systems that improve health and advance equity. 

Eligibility 
Each invited institution may submit a single application from a full-time faculty member. United States citizenship is not required. To encourage the support of junior faculty, applicants are ineligible if at the time of application, they have combined federal and nonfederal funding totaling $500,000 or more in direct costs during the first year of the Geneen Award. This figure refers to external funding only and not an applicant’s start-up package, other intramural support, or the Geneen Award itself. Applicants may hold a K Award or be in the R00 phase of a K99/R00 as long as those award amounts, combined with other funding, do not exceed these specified limits. 

Pending Federal and Non-Federal Support 
Applicants who have pending R01s or other large applications to the NIH and other agencies are encouraged to submit proposals to the Geneen Trust. Notification of funding after the application date will not impact eligibility for a Geneen Award. However, it is the responsibility of applicants to contact GeneenAwards@hria.org as soon as they are notified of any new funding. 

Apply to Internal Competition // Limit: 1 // Tickets Available: 1

Limiting Language
The Foundation will consider only one proposal from an organization in any calendar year.

Program Overview
The Foundation supports projects and applied research that:

• Generate local or regional solutions to problems affecting the quality of the environment and human life;
• Advance local leadership and promote professional development in the conservation, agricultural, and health sciences;
• Develop the capacity of local organizations and coalitions; and
• Address challenges in the field. 

The Foundation prefers to support projects that address under-funded issues and geographic areas.

The Foundation funds applied research, pilot projects, new initiatives, training, and technical assistance, rather than ongoing support for programs that are already well underway.  An important goal for the Foundation is to provide seed money to help promising projects, organizations, and individuals develop the track record they need to attract major foundation funding in the future.

Fields of Interest

The following are examples of the Foundation’s areas of interest within the fields of conservation, food, and health, and are not meant to be exclusive.

Conservation

Conservation grants promote environmental conservation through field research, projects, and advocacy that:

• Protect biodiversity and preserve natural resources.
• Help mitigate the adverse effects of climate change.
• Build the scientific and technical capacity of local conservation organizations and promote local, regional, and international partnerships.
• Increase engagement between scientists, local communities and organizations, and decision-makers.
• Partner with indigenous communities and local people.

Food

Grants in the food and agriculture program area focus on targeted demonstration, applied-research, and inquiry-based projects that support on-the-ground science and advocacy. Such efforts build capacity for self-sufficiency and resilience to climate change, enhance food security, strengthen local food systems, and support healthy nutrition through projects that: 

• Develop and promote sustainable agricultural practices
• Build the capacity of small-scale farmers.
• Advance farmer research and research partnerships.
• Develop environmentally sound and affordable approaches to control pests and diseases affecting important local food crops.
• Promote indigenous food sovereignty and knowledge systems.
• Address challenges of uptake and scalability through new methods of extension, education, and technology transfer.

Health

The Foundation supports efforts that test new ideas and approaches that promote public health, with a special emphasis on reproductive health and family planning and their integration with other health promotion activities.  It favors community-level disease prevention and health promotion projects and efforts that help strengthen regional and country public health systems over disease diagnosis, treatment, and care provided by clinics, hospitals, and humanitarian aid programs.

Activities that help increase capacity include applied research, program development, technical assistance, and training projects that:

• Promote reproductive health and family planning.
• Address issues related to mental and behavioral health.
• Address issues relating to pollution and environmental health.
• Increase the understanding of zoonotic and neglected tropical diseases.
• Address issues relating to nutrition and health.

Key Priorities

In all of its areas of interest, the Foundation gives priority to projects that have the potential to advance the field, build local capacity, promote replication, influence public opinion and policy, affect systems change, and benefit people beyond the immediate project and its local context.

Eligibility

The Foundation supports local, state, and regional organizations in Africa, Asia, the Caribbean, Latin America, and the Middle East in the countries where the projects are based.  It also supports organizations located in upper-income countries working with local partners in these areas.  It does not support projects in post-Soviet states or Balkan states.

Most types of organizations that can provide evidence of their non-governmental status or charitable purpose are eligible to apply, including non-governmental organizations, nonprofit organizations; civil society organizations; community-based organizations; and colleges, universities, and other academic institutions.

Government agencies and religious organizations may be included as project partners but are not eligible for direct funding.

The Foundation does not typically fund:

• Overhead or indirect project costs
• General operating support
• Direct food, health or other humanitarian aid
• Eco-tourism
• Buildings and capital improvements
• Projects ultimately intended for private gain.  All intellectual property developed with the grant should be public.
• Salaries for Executive Directors of U.S. and European-based organizations.
• Project expenses incurred before the grant is awarded.

Grant-Making Policies and Procedures

There is no minimum or maximum grant size. It is anticipated that most grants will fall in the $25,000-$50,000 per year range.

Request Ticket for "OPEN" Focus Area // Limit: 1 Phase I or Phase II Application per Focus Area (99 total) - Each PI may only submit one proposal but can be senior/key personel on an unlimited number of proposals

Important Institutional Deadlines: 
Ticket Request Deadline -  The deadline to request a ticket for this funding opportunity is 5:00PM Monday, April 6. After this time, no additional tickets will be issued. 

Engineering Faculty - the cutoff for engineering faculty request limited submissions tickets is 5:00pm 3/30. ERAS is unable to provide support to tickets requested after this time. 

Topic Area 1: Reenvisioning Advanced Manufacturing and Industrial Productivity // Limit: 6 // Tickets Available: 3
Focus Area A - Agentic AI-Driven Chemical Manufacturing (BES) - OPEN
Focus Area B - AI-Driven Materials Processing (BES) - H. Kim (Civil and Architectural Engineering and Mechanics)
Focus Area C - AI-Enabled Manufacturing for Extreme Energy Systems (FES) - OPEN 
Focus Area D: Digitalization of Industrial Processes (ITO) – M. Shafae (Systems and Industrial Engineering)
Focus Area E: AI-Enabled Smart Manufacturing (AMMTO) - P. Satam (Systems and Industrial Engineering) 
Focus Area F: Energy Material Manufacturing (AFFO) - OPEN

Topic Area 2: Scaling the Biotechnology Revolution // Limit: 5 // Tickets Available: 2
Focus Area A: Biomolecular Science (BER) – T. Wheeler (Pharmacy Practice and Science)
Focus Area B: Genotype to Phenotype (BER) L. Meredith (School of Natural Resources and the Environment
Focus Area C: Predictive Engineering of Microbial Communities (BER) – M. Tfaily (Environmental Sciences) 
Focus Area D: Bio Design (BER) - OPEN
Focus Area E: AI-Enabled Biological Reaction Engineering, Bioreactor Design, Process Scale-up
and Integration (AFFO) - OPEN

Topic Area 3: Securing America’s Critical Minerals Supply // Limit: 7 // Tickets Available: 3
Focus Area A: Resource Mapping and Development (AMMPTO) – J.G. Duan (Civil and Architectural Engineering and Mechanics)
Focus Area B: AI-Enabled Materials Discovery and Engineering (AMMTO) – J.L. Bredas (Chemistry and Biochemistry)
Focus Area C: Economic Modeling and Market Analysis (ASO) - OPEN
Focus Area D: Extraction and Processing Technologies (AMMPTO, AMMTO) - N. Risso (Mining Engineering and Mineral Resources)
Focus Area E: Geological Finder/Keepers – Y. Song (Hydrology and Atmospheric Sciences)
Focus Area F: Connections for Isolation (BES) - OPEN 
Focus Area G: Biological Pathways to CMM (BER) - OPEN

Topic Area 4: Delivering Nuclear Energy that is Faster, Safer, Cheaper // Limit: 8 // Tickets Available: 8
Focus Area A - Accelerated Nuclear Power Plant Design and Licensing: Create an automated
process to enable rapid design, including safe and secure autonomous monitoring
and control of plant operations, licensing considerations, and rapid deployment of
advanced nuclear technologies using AI - OPEN
Focus Area B - Autonomous Power Plant Operations: Develop AI digital twin systems that
interpret plant operational data in real time, detect anomalies, and recommend
preemptive actions to maintain safety and operational performance - OPEN
Focus Area C: AI-Assisted Manufacturing and Construction: Support site selection, born certified
manufacturing, construction, supply chain reliability, and factory modular
production methods with AI technologies - OPEN 
Focus Area D: Autonomous Research and Development: Condense nuclear material research and
qualification timeframes using AI-driven pipelines for modeling, characterization,
evaluation, and qualification, while integrating decades of global historical
irradiation data - OPEN
Focus Area E: Accelerated Fuel Cycle Facility Design and Licensing to Secure the Domestic Fuel
Supply: Create automated processes to enable rapid design, licensing
considerations, and accelerated deployment of advanced fuel cycle technologies
using AI - OPEN
Focus Area F: AI-Assisted Site Characterization: Accelerate waste disposition site characterization
through AI Modeling - OPEN
Focus Area G: AI-Assisted End Disposition Design: Concept Design for Disposal of Used Nuclear
Fuel and Reprocessed Fuel Waste Streams - OPEN
Focus Area H: Development, Utilization and/or Adoption of AI and ML Tools to Support the
Efficient Review, Classification and Release of Legacy Documents to the Nuclear
Industry - OPEN

Topic Area 5: Accelerating Delivery of Fusion Energy // Limit: 7 // Tickets Available: 5
Focus Area A: Structural Materials (FES) - OPEN
Focus Area B: Plasma-Facing Materials (FES) - OPEN
Focus Area C: Advancing Confinement Approaches – C. Chan (Steward Observatory and Department of Astronomy)
Focus Area C: Advancing Confinement Approaches (FES) - OPEN
Focus Area D: Fuel Cycle and Tritium Processing (FES, NE) - OPEN
Focus Area E: Tritium Breeding Blankets (FES, NE) - OPEN
Focus Area F: Fusion Plant Engineering and System Integration – D. Ebert (Electrical and Computer Engineering)
Focus Area G: Plasma Science and Technology (FES) - OPEN

Topic Area 6: Transforming Nuclear Restoration and Revitalization // Limit: 3 // Tickets Available: 3
Focus Area A: EM AI R&D Roadmap Implementation (EM-3.2, ASCR, LM) - OPEN
Focus Area B: Scale-Bridging AI Foundation Model (EM-3.2, ASCR) - OPEN
Focus Area C: Treatment Process Optimization (EM-3.2, ASCR) - OPEN

Topic Area 7: Discovering Quantum Algorithms with AI // Limit: 5 // Tickets Available: 3
Focus Area A: Application-aware Error Correction (ASCR) - OPEN
Focus Area B: Computational Tools for Fault Tolerant Quantum Computational Science (ASCR) - OPEN
Focus Area C: Hybrid Quantum-Classical Optimization Algorithms (BES) - J. Chen (Electrical and Computer Engineering)
Focus Area D: Quantum Algorithms for Nonlinear Plasma Physics (FES) - OPEN
Focus Area E: Quantum Advantage for Nuclear and Hadronic Systems (NP, HEP) – P. Siwach (Physics)

Topic Area 8: Realizing Quantum Systems for Discovery // Limit: 4 // Tickets Available: 2
Focus Area A: AI for Quantum Systems Design - OPEN
Focus Area B: AI for Control of Quantum System (HEP, NP) - OPEN
Focus Area C: AI for Quantum Imaging and Sensing (HEP, NP) – D. Soh (Wyant College of Optical Sciences) 
Focus Area D: AI for Quantum Computing and Networking (ASCR) – N. Rengaswamy (Electrical and Computer Engineering)

Topic Area 9: Recentering Microelectronics in America // Limit: 10 // Tickets Available 4
Focus Area A: Angstrom (sub-1-nm) Scale Microelectronics Manufacturing (AMMTO) - OPEN
Focus Area B: Materials and Architectures for Non-von Neuman Computing Devices (BES) – X. Yan (Materials Science and Engineering)
Focus Area C: AI-Driven Architecture Design (ASCR) – J. Dass (Electrical and Computer Engineering)
Focus Area D: 3D Non-Volatile Compute-In-Memory Technology (ASCR) – S. Salehi (Electrical and Computer Engineering) 
Focus Area E: Physics-Based Circuit Design, Simulation, and Emulation (ASCR) – H. Yang (Electrical and Computer Engineering)
Focus Area F: Microelectronics in Harsh Environments (HEP) - J. Roveda (Electrical and Computer Engineering)
Focus Area G: Plasma-Enabled Microelectronics Manufacturing (FES) -OPEN
Focus Area H: Power Electronics and Communication Networks (ASCR) - OPEN
Focus Area I: Low-temperature Electronics for Sensors and Computation (ASCR, HEP) – M. Hassan (Physics)
Focus Area J: Transform Neuromorphic Computing Connectivity, Communication, and System
Hardware Integration (ASCR) - OPEN

Topic Area 10: Securing U.S. Leadership in Data Centers // Limit: 2 // Tickets Available: 2
Focus Area A: Data Center Load Flexibility (ITO) - OPEN
Focus Area B: Data Center Thermal Management (ITO) - OPEN

Topic Area 11: Achieving AI-Driven Autonomous Laboratories // Limit: 5 // Tickets Available: 2
Focus Area A: Advanced Robotics for Dynamic Laboratory Environments (ASCR) - S. He (Electrical and Computer Engineering)
Focus Area B: AIOps - AI for Network Operations (ASCR) - OPEN
Focus Area C: AI-Accelerated Science: Correlation to Understanding (BES) - A. Black (Information Science)
Focus Area D: AI-Enabled Diagnostics and Remote Handling (FES) - B. Liu (Electrical and Computer Engineering)
Focus Area E: Accelerate the design and prototyping of neuromorphic computing circuit primitives for robotic embodied physical artificial intelligence (ASCR) - OPEN

Topic Area 12: Designing Materials with Predictable Functionality // Limit: 7 // Tickets Available: 4
Focus Area A: Functional to Quantum Materials (BES) - OPEN
Focus Area B: Structural Materials (BES, FES, AMMTO) - M. Latypov (Materials Science and Engineering) 
Focus Area C: Biomolecular Materials (BES) - OPEN
Focus Area D: Plasma-Facing Materials (FES) - OPEN
Focus Area E: Targetry by Design (IRP) - OPEN
Focus Area F: AI-Enabled Materials Discovery, Development, and Qualification (AMMTO) - M. Beidaghi (Aerospace and Mechanical Engineering)
Focus Area G: Electrochemical Energy Conversion Catalyst Discovery and Scale up (AFFO) - Z. Yan (Chemistry and Biochemistry)

Topic Area 13: Enhancing Particle Accelerators for Discovery // Limit: 2 // Tickets Available: 2
Focus Area A: AI-driven Accelerator Facilities (BES, HEP, IRP, NP) - OPEN
Focus Area B: Integration of Digital Twins for Fusion Systems and Actuators (FES) - OPEN

Topic Area 14: Unifying Physics from Quarks to the Cosmos // Limit: 3 // Tickets Available: 1
Focus Area A: Foundation Models of Particle Interactions and Cosmic Physics – S. Pandey (Astronomy and Steward Observatory)
Focus Area B: AI Accelerated DUNE Science (HEP) - OPEN 
Focus Area C: Expedited Discovery from High Complexity and Petabyte-Scale Datasets (HEP, NP) - T. Eifler (Astronomy and Steward Observatory) 

Topic Area 15: Predicting U.S. Water for Energy // Limit: 3 // Tickets Available: 1 
Focus Area A: Cloud Microphysics and Atmospheric Turbulence – X. Dong (Hydrology and Atmospheric Sciences)
Focus Area B: Water and Energy (BER) - A. Bennett (Hydrology and Atmospheric Sciences)
Focus Area C: Weeks to Years Prediction (BER) - OPEN

Topic Area 16: Scaling the Grid to Power the American Economy // Limit: 3 // Tickets Available: 1 
Focus Area A: Grid Modeling and Analysis (OE, CMEI-IESO, SC-ASCR) – M. Chertkov (Mathematics)
Focus Area B: Grid Operations Optimization (OE, CMEI-IESO, SC-ASCR) - OPEN
Focus Area C: Uncertainty Quantification (SC-BER, SC-ASCR, OE, CMEI-IESO) – R. Tandon (Electrical and Computer Engineering)

Topic Area 17: Unleashing Subsurface Strategic Energy Assets // Limit: 3 // Tickets Available: 2
Focus Area A: Chemical and Hydrologic Transport in Subsurface – S. Saleska (Ecology & Evolutionary Biology)
Focus Area B: Evolution of Fractures in the Upper Crust (BES) - OPEN
Focus Area C: Control of Subsurface Fractures (HGEO) - OPEN

Topic Area 18: HPC Code Curation, Translation, and Development for Accelerated Scientific Discoveries  // Limit: 7 // Tickets Available: 7
Focus Area A: AI-Driven Code Porting and Optimization (ASCR) - OPEN
Focus Area B: Automated Scientific Problem-to-Code Generation (ASCR) - OPEN 
Focus Area C: Neuro-Symbolic Agents for Code Development (ASCR) - OPEN
Focus Area D: Performance Prediction and Feedback Loops (ASCR) - OPEN
Focus Area E: Trustworthy AI for Scientific Software (ASCR) - OPEN
Focus Area F: Multi-Modal Data Integration for Code Intelligence (ASCR) - OPEN
Focus Area G: Partnerships for HPC AI Advancement (ASCR, AMMTO) - OPEN

Topic Area 19: AI for Scientific Reasoning // Limit: 3 // Tickets Available: 1
Focus Area A: Trustworthy Mathematical and Symbolic Reasoning (ASCR) – E. Blanco (Computer Science)
Focus Area B: Hypothesis Generation from Multi-Modal Data (ASCR) - A. Zabludoff (Astronomy and Steward Observatory)
Focus Area C: Composable and Modular Foundation Models (ASCR) - OPEN

Topic Area 20: Cybersecurity for AI-Driven Science Workflows // Limit: 3 // Tickets Available: 0
Focus Area A: AI for Adversarial Robustness and Resilience– M. Krunz (Electrical and Computer Engineering)
Focus Area B: Data Provenance and Integrity Verification (ASCR) – D. Alharthi (College of Information Science) 
Focus Area C: Real-Time Attack Detection and Mitigation for AI Models (ASCR) – M. Li (Electrical and Computer Engineering)

Topic Area 21: Artificial Intelligence in Fluid Flow for Energy Components and Technologies // Limit: 3 // Tickets Available: 1
Focus Area A: Physics-Informed AI for Complex Flow Modeling – K. Kratter (Astronomy and Steward Observatory)
Focus Area B: AI-Driven Design and Control for Performance and Durability (IESO, ASCR) - OPEN
Focus Area C: Data-Driven Operational Intelligence and System Resilience (IESO) – L. Zhang (Civil and Architectural Engineering and Mechanics)

Limiting Language
Applicant institutions are limited to no more than one application as the lead institution per focus area for Phase I and Phase II applications combined. Phase II applications must list a primary focus area but will have the option to list secondary focus areas. The primary focus area will be used for determining limitations on institutional submissions.

There is no limitation to the number of applications for which the institution is not the lead in a multi-institution team using collaborative applications.

The PI on an application may also be listed as a senior or key personnel on an unlimited number of separate submissions but can be the lead PI on only one application.  However, the PI on an awarded Phase I award may submit a Phase II proposal as part of the FY27 go/no-go decision process.  

The full RFA is linked here. 

Executive Summary 
The DOE Office of Science (SC), Office of Critical Minerals and Energy Innovation (CMEI), Office of Environmental Management (EM), Office of Nuclear Energy (NE), Office of Electricity (OE), and Hydrocarbons and Geothermal Office (HGEO) hereby announce interest in receiving applications from interdisciplinary teams addressing the Genesis Mission National Science and Technology Challenges to accelerate scientific discovery and research and development (R&D) workflows using novel artificial intelligence (AI) models and frameworks. By achieving AI advantage, these teams will advance the DOE's mission and ensure America’s security and prosperity by addressing energy, environmental, and nuclear challenges through science and technology. Teams are encouraged to leverage the extensive scientific and data resources of the DOE/National Nuclear Security Administration (NNSA), the National Laboratories, U.S. industry, and academia. The resulting AI models and workflows, if successful, may be integrated into the American Science Cloud. 

DOE is soliciting new FY26 Phase I small team and Phase II large team applications in the following topic areas: advanced manufacturing, biotechnology, critical materials, nuclear fission, nuclear fusion, quantum information science, semiconductors and microelectronics, discovery science, and energy (see specific focus areas in Section III Program Descriptions). 

In addition, this RFA will remain available to allow the recipients of FY26 Phase I awards to apply for larger team Phase II awards. In a few weeks, DOE plans to amend the RFA to clarify the LOI and application guidelines for FY26 Phase II awards. In FY27, DOE plans to amend the RFA or to issue an alternative funding opportunity to update the topic and focus areas to allow a second competition of Phase I small team applications and Phase II large team applications. 

Additional applications for Phase I and Phase II may be submitted after the corresponding deadline listed on the cover of this RFA, however, DOE reserves the right to decline such applications without review.

Request Ticket // Limit: 1 // Tickets Available: 1

Limiting Language
Each program/institution may submit one LOI/applications in the Survivorship and Supportive Care Research Grant Award category for the 2026 cycle. 

Note: The limited submissions policy exception detailed in other program guidelines is not applicable for the Survivorship and Supportive Care Research Grant Award category for the 2026 cycle. 

Grant Overview
These grants are for specific one-year research projects which are hypothesis-driven and focus on areas related to survivorship and supportive care of children and adolescents with cancer. Applications are accepted from Ph.D., D.N.P., M.D./D.O. holders.  

Examples include but are not limited to: studies related to the burden of morbidity, cause-specific mortality, understanding the pathogenesis of treatment-related complications, patient-reported outcomes or quality of life, health communication, health promotion, and psychosocial support across the trajectory from diagnosis to survivorship or end-of-life care.

• Allied World – St. Baldrick’s Survivorship and Supportive Care Research Grant LOI instructions 
• Allied World – St. Baldrick’s Survivorship and Supportive Care Research Grant Award Guidelines 

Request Ticket (include lab and approval message from lab's PI) // Limit: 1 predoc, postdoc, or faculty member per lab

Limiting Language
Only one applicant per lab may apply in the Drug Delivery Program. Labs must select either a predoc, a postdoc, or a faculty member.

Request Ticket (include lab and approval message from lab's PI) // Limit: 1 predoc, postdoc, or faculty member per lab

Limiting Language
Only one applicant per lab may apply in the Drug Delivery Program. Labs must select either a predoc, a postdoc, or a faculty member.

Internal Competition Undergoing Peer Review // Limit: 8 Concept Papers, 2 Phase I Proposals (1 Medical Research, 1 Science and Engineering)

 Program Description

Full sponsor guidelines: https://www.wmkeck.org/research-overview/

The mandate of the W.M. Keck Research Program is to support pioneering discoveries in Science, Engineering, and Medical Research.  The Foundation funds the high-risk and high-impact work of leading researchers to lay the groundwork for new paradigms, technologies, and discoveries that will save lives, provide innovative solutions and add to our understanding of the world.

Keck funded projects are distinctive and novel in their approach, question the prevailing paradigm, or have the potential to break open new territory in their field.  We prioritize grants that pioneer biological and physical science research and engineering, including the development of promising new technologies, instrumentation or methodologies.

Fit Self-Test: A Keck-ready idea can answer “yes” to most of the following questions:

• Does it discover how something works?
• Does it challenge an existing assumption?
• Is failure still scientifically valuable?
• Would federal agencies likely say, “too early”?

Keck Prioritizes:

• Work that is paradigm shifting, or challenges a prevailing hypothesis
• Work that creates a new field, or bridges disparate fields
• Work that departs from current approaches or challenges existing assumptions or frameworks
• Fundamental basic science questions focused on how systems work and the underlying mechanisms that govern them
• Discovery-driven logic
• Research where failure is informative

Keck Disfavors:

• Clinical or translational research (i.e., development of therapeutics)
• Outcome or patient impact framing
• Biomarkers as endpoints
• Engineering for its own sake
• Large mammal studies when they function as clinical or validation trials
• Already funded or derivative work

Important notes:

• Keck seeks to fund basic science that advances fundamental understanding
• Keck funds science, not engineering – unless engineering is essential to answer a scientific question
• Keck funds medical research, not clinical research
• Federal rejection is not required, but Keck fills gaps where federal agencies are too risk adverse.
• Keck does not consider tools, platforms, or methods as the primary idea. Tools, AI, and engineering may be supported only if required to answer a basic scientific question.