Biomedical, Clinical & Life Sciences

J. Barton (BOI5 Instiutue) 


UArizona may submit one proposal to this funding program.

BioFoundries is an infrastructure program from the National Science Foundation (NSF) that is designed to accelerate advances in the biological sciences, chemical biology, biotechnology, and bioengineering via access to modern infrastructure, technology, and capacity. BioFoundries will provide the intellectual, technical, digital, and physical frameworks needed for tight integration of technology innovations and applications with foundational interdisciplinary research and training, by: 

1. serving as access points for new biological technologies, workflows, processes, automations, and knowledge-bases to enable transformative discoveries;
2. catalyzing new innovations and transformative discoveries by supporting in-house and external user-initiated research programs that take full advantage of technological and methodological advances;
3. continuing to develop novel technologies, workflows, processes, automations, and knowledge-bases that are both forward-looking and user-responsive;
4. increasing the reproducibility of life science discoveries and data and knowledge sharing capabilities;
5. training the next generation of the scientific workforce; and
6. facilitating pathways to translation.

Leveraging lessons learned from existing national and international biofoundries, NSF encourages researchers to consider a diversity of models (centralized, distributed, consortium) in the design and implementation of BioFoundries. Each BioFoundry should enclose a scientific ecosystem, that includes in-house research scientists across all relevant disciplines supported by NSF, technical staff including cyberinfrastructure experts, external users, and other contributors who, collectively, form a community of practitioners and share tools, reagents, workflows, software, samples, and data. Knowledge sharing should be a central tenet, designed to strengthen collaborations among researchers and enable them to work in new ways and to foster new modalities of research and education/training, for the purpose of accelerating discovery and advancing development. BioFoundries should promote diversity, equity, inclusion, and accessibility in their in-house programs and external user programs. BioFoundries should also promote new avenues for translating such knowledge and technology broadly in ways that benefit society.

S. Hamilton (Cellular and Molecular Medicine)

UArizona may submit one application.

Program Focus and Overview: The Harold S. Geneen Charitable Trust Awards Program for Coronary Heart Disease Research supports research in the area of the prevention of coronary heart disease or circulatory failure, and improving care for these patients. The Program focuses on basic and translational scientific research. Clinical studies are currently ineligible.

In accordance with Mr. Geneen’s directives the Program supports smaller, mid-sized institutions “rather than major universities or medical complexes which have a demonstrated capacity to raise funds from the public generally.”

Applications examining the intersection of coronary heart disease and/or congestive heart failure and COVID-19 or similar viral illnesses are highly encouraged to apply.

Eligibility: Each invited institution may submit a single application from a full-time faculty member. United States citizenship is not required. Junior faculty and those with less than $500,000 in direct costs funding at the time of application are encouraged to apply.

M. Dodson ( Pharmacy)

UArizona is allowed a maximum of one nomination per grant cycle to one of the Pathway Program Award types: Initiator or Accelerator.

Pathway to Stop Diabetes has a simple, yet revolutionary goal: to find scientists at the peak of their creativity and provide them with the flexibility and resources they need on the road to breakthrough discoveries. We attract and retain brilliant scientists in diabetes. Our three areas of focus—awarding research grants, providing access to scientific and career mentoring from leading diabetes researchers, and creating a diabetes think tank—are each key components of a unique formula to cultivate the next generation of leaders, whose discoveries will stop diabetes and all of its burdens once and for all.

Initiator Award (INI)

• Award Term: Up to 7 years
• Applicant: Postdoctoral Fellow
• Maximum Funding: Up to $100,000/year in Phase 1, Up to $325,000/year in Phase 2
• Support: Project support & PI salary
• Indirect Support: Up to 10% of directs in Phase 1, Up to 30% of directs in Phase 2
• Project % Effort Required: 75-100% effort in Phase 1, 50-75% effort in Phase 2
• Citizenship: Authorized to work in U.S. or U.S. possessions
• Description: This two-phased award is designed to support the transition of scientists from mentored training to independent research faculty.
• Eligibility: Eligible applicants must currently be in research training positions (post-doctoral fellow, research fellowship) and have no more than seven years of research training following terminal doctoral degree. Applicants cannot concurrently hold an NIH K99/R00 grant. Candidates must be identified through institutional nomination; applications will be accepted only from individuals with the appropriate institution support.
• Support: Awards provide two distinct phases of research support: Phase 1 provides up to two years of support for mentored training at a maximum of $100,000 per year (including 10% indirect costs), Phase 2 provides up to five years of support for independent research at a maximum of $325,000 per year (including 30% indirect costs). Maximum combined support for Phase 1 and Phase 2 is $1,625,000.

Accelerator Award (ACE)
 

• Award Term: Up to 5 years
• Applicant: Early Career Faculty
• Maximum Funding: $325,000/year
• Support: Project support & PI salary
• Indirect Support: Up to 30% of directs
• Project % Effort Required: 25-50% effort
• Citizenship: Authorized to work in U.S. or U.S. possessions
• Description: This award is designed to support exceptional, independent early-career researchers who have distinguished themselves as promising investigators and are in the beginning stages of establishing successful, sustainable diabetes research programs.
• Eligibility: Awards are available to early-career diabetes investigators proposing innovative and ambitious diabetes-related research programs. Applicants must hold faculty positions and have demonstrated independent productivity in diabetes research. Applicants may currently hold independent NIH funding (K, U or R awards, including an initial R01/U01) but must not have applied for (regardless of outcome), or received, an R01/U01 renewal or a second R01/U01 award. Candidates must be identified through institutional nomination; applications will be accepted only from individuals with the appropriate institution support.
• Support: Awards provide five years of research support at a maximum of $325,000 per year (including 30% indirect costs), for a total of $1,625,000.

Institutionally coordinated submission - Contact RDS to apply


R. Liang (Optical Sciences) - S10 SIG PAR-22-080

ORIP's S10 Instrumentation Grant Programs support purchases of state-of-the-art commercially available instruments to enhance research of NIH-funded investigators. Instruments that are awarded are typically too expensive to be obtained by an individual investigator with a research project grant. Every instrument awarded by an S10 grant is to be used on a shared basis, which makes the programs cost-efficient and beneficial to thousands of investigators in hundreds of institutions nationwide.

S10 awards are made to domestic public and private institutions of higher education, as well as nonprofit domestic institutions, such as hospitals, health professional schools, and research organizations. To be eligible for an S10 award, an institution must identify three or more principal investigators with active NIH research awards who demonstrate a substantial need for the requested instrument.

Awards are issued for 1 year, and matching funds are not required. However, ORIP expects institutions that compete for S10 awards to provide an appropriate level of support for the associated infrastructure, such as the space to house the instrument, technical personnel, and post-award service contracts for instrument maintenance and operation.

Types of instruments supported by S10 funding include, but are not limited to, X-ray diffraction systems, nuclear magnetic resonance (NMR) and mass spectrometers, DNA and protein sequencers, biosensors, electron and confocal microscopes, cell-analyzers, and biomedical imagers.

Active RFPs are: 

• Basic Instrumentation Grant Program (BIG) – UArizona is not eligible to apply to this funding program
• Shared Instrumentation Grant Program (SIG) – The SIG Program funds grant awards in the $50,000 to $600,000 range.
• High-End Instrumentation Grant Program (HEI) – The HEI Program funds grant awards in the $600,001 to $2,000,000 range.
   

There is no restriction on the number of applications an institution (as identified by a specific Unique Entity Identifier (UEI) can submit to the companion funding opportunities (Shared Instrumentation Grants (SIG) and/or High-End Instrumentation (HEI) Grant Programs) each year, provided the applications request different types of equipment. Concurrent BIG, SIG or HEI applications for the same instrument (or the same type of instrument with added special accessories – for example, to meet the HEI budget requirement) are not allowed unless documentation from a high-level institutional official is provided, stating that this is not an unintended duplication, but part of a campus-wide instrumentation plan. Applicants are advised to discuss with the BIG Scientific/Research Contact (Section VII) potential duplicates before submitting two applications for the same type of instrument. A single application requesting more than one type of instrument (for example, a spectrometer and a microscope) is not responsive to this FOA and will not be reviewed.

The sponsor has confirmed that the  Women in STEM2D Scholars Program is under review; therefore, the solicitation won't be open during 2023. 

• K. Renner (Orthopaedic Surgery) - Engineering discipline
• K. Rodriguez (Veterinary Medicine) - Science discipline
• A. Ryan (Civil and Architectural Engineering and Mechanics) -  Technology discipline

Math, Manufacturing & Design disciplines are still available. 

UArizona may submit a limit of 6 proposals, one per award category: Science, Technology, Engineering, Math, Manufacturing & Design. 

When the 2023 solicitation and guidelines are posted by the sponsor, the internal competition will be updated. 

The Johnson & Johnson Scholars Award Program aims to fuel development of female STEM2D leaders and feed the STEM2D talent pipeline by awarding and sponsoring women at critical points in their careers, in each of the STEM2D disciplines: Science, Technology, Engineering, Math, Manufacturing and Design. The awards will fund one woman per STEM2D discipline who has completed her advanced degree, who is working as an assistant professor (or global equivalent faculty position) and who is not yet tenured at an accredited university, institution or design school. The goal is to fuel the research passion of the awarded women and inspire career paths in their respective STEM2D fields. Johnson & Johnson is looking to identify global women leading in both their research fields and leading as mentors, to be a vision for girls and other women in STEM2D.

The Scholars Award is a three-year award in the gross amount of $150,000, which will be paid to the University (the “Recipient”) for the benefit of the Johnson & Johnson Scholar and her research, with the understanding that the Recipient will administer the funds. The Scholars Award will be paid in three (3) installments of U.S. $50,000 per year of the three-year scholarship period, payable in 2023, subject to compliance with the terms and conditions of the program’s Agreement. Winners achievements will also be showcased at a symposium.

Judges will use the following criteria to evaluate the applications:

• Scientific/technical expertise exhibited
• Novelty/innovation of the research
• Potential impact of the research
• Feasibility of the research

You must be a woman working in the field(s) of Science, Technology, Engineering, Mathematics, Manufacturing and Design (STEM2D).

You must be an early to mid-career women working within a STEM2D university department at the time of application at an accredited academic university, institution or design school. Examples include a non-tenured assistant professor, assistant professor or associate professor.

The female scholar should have a minimum degree for the appropriate field:

• Science; M.D., Ph.D.
• Technology; Ph.D.
• Engineering; Ph.D.
• Math; M.S., Ph.D.
• Manufacturing; Ph.D.
• Design; M.A., M.S., MDes, MArch, MFA, MLA, Ph.D.

Limit: 2  // PIs: 
M. Kwinn   ( Systems and Industrial Engineering /Engineering Management)
H. Budinoff (Systems and Industrial Engineering)

UArizona may submit two proposals to this funding program. 

VentureWell Course and Program (C&P) Grants of up to $30,000 are awarded to US higher education institutions to support curriculum to grow and expand the entrepreneurial ecosystem in order to engage students in science and technology (S&T) innovation and entrepreneurship (I&E). Ideally, C&P Grant funding should act as a catalyst for increased entrepreneurial activity and help faculty and universities leverage other opportunities to launch and/or grow their I&E ecosystems. 

C&P grants may be used to strengthen existing curricular programs or to build new, pedagogically inclusive courses and programs that engage student teams in developing and pursuing scalable solutions to real-world needs through S&T I&E. The end goal is to support diverse groups of faculty, staff, and students in collaborating to develop novel inventions and technologies that have positive environmental and social impact.

Activities supported by C&P grants should lead to effective courses and programs that are sustained by the institution, lead to the formation of student teams by leveraging experiential learning practices, and expand opportunities for learning across S&T I&E.

C&P grant proposals may include plans to create or improve an individual course, course sequence, minor, major, certificate program, or other co- and extracurricular programs, including non-credit programs, that are directly tied to and support I&E-focused curriculum. S&T focus area may include, but are not limited to:

• General (science- and technology-based) entrepreneurship
• Sustainable technologies (new materials, clean tech, green energy, and chemistry innovation)
• Climate change solutions (technology to mitigate and/or adapt to climate change), especially technologies that support communities most impacted by climate change
• Biomedical and healthcare innovation
• Technologies that address poverty alleviation and basic human needs

Limit: 1  // PI: M. Romero-Ortega (Biomedical Engineering)

 

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The overarching goal of this R25 program is to support educational activities that encourage individuals from diverse backgrounds, including those from groups underrepresented in the biomedical and behavioral sciences, to pursue further studies or careers in research.

To accomplish the stated over-arching goal, this FOA will support educational activities with a primary focus on:

• Courses for Skills Development

• Research Experiences

The ESTEEMED program is designed to foster the development of undergraduate freshmen and sophomores from diverse backgrounds to pursue further studies and careers in bioengineering or STEM fields relevant to NIBIB’s scientific mission. Applications are encouraged to propose integrated educational activities that include 3 elements: a summer bridge program for incoming freshmen, and in the freshman and sophomore years, academic year activities and summer research experiences. The ESTEEMED program is intended to expose students to bioengineering research early in their college careers while also providing students didactic, mentoring and career development opportunities. This will prepare students to join, in their junior and senior years, an honors program that promotes STEM and entrance into a Ph.D. program. The ultimate goal is for the participants to pursue a doctoral degree and a subsequent research career in bioengineering or NIBIB-relevant field.

Components of Participating Organizations:
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

X. Ding (Pharmacy) - Competitive resubmission. 

UA may submit one proposal.

The National Institute of Environmental Health Sciences (NIEHS) is announcing the continuation of the Superfund Hazardous Substance Research and Training Program, referred to as Superfund Research Program (SRP) Centers. SRP Center grants will support problem-based, solution-oriented research Centers that consist of multiple, integrated projects representing both the biomedical and environmental science and engineering disciplines; as well as cores tasked with administrative (which includes research translation), data management and analysis, community engagement, research experience and training coordination, and research support functions. The scope of the SRP Centers is taken directly from the Superfund Amendments and Reauthorization Act of 1986, and includes: (1) advanced techniques for the detection, assessment, and evaluation of the effect on human health of hazardous substances; (2) methods to assess the risks to human health presented by hazardous substances; (3) methods and technologies to detect hazardous substances in the environment; and (4) basic biological, chemical, and physical methods to reduce the amount and toxicity of hazardous substances.

S. Carvajal (Health Promotion Sciences)

This Notice of Funding Opportunity (NOFO) will provide funding to academic research centers to participate in the network of Health Promotion and Disease Prevention Research Centers (PRC Network) to:Establish and maintain a multi-disciplinary prevention research center (Center) that conducts high-quality applied health promotion and disease prevention public health research (hereafter referred to as prevention research); Conduct one (1) dissemination and implementation (D&I) core research project that utilizes (a) an evidence-based public health intervention (EBI) and (b) an equitable and evidence-based community engaged approach – e.g., community-based participatory research (CBPR), to address a leading cause of chronic disease morbidity or mortality in a population experiencing high levels of health disparities or health inequities;Collaborate with partners that can help translate research findings into practice within the research community (hereafter referred to as partners that translate), promote sustainability beyond the core research project, and facilitate dissemination;Disseminate research findings to community, practice, and academic audiences; Serve as a resource to other PRCs, as part of the PRC Network, for adapting, implementing, evaluating, disseminating, and translating evidence-based public health interventions at local, state, tribal, or national levels; andParticipate in the PRC Network to (a) leverage the expertise of the network members to inform individual core research project and center activities (as needed) and (b) advance the network’s collective impact in public health prevention research, policy, and practice.

Institutionally coordinated submission

UArizona may not submit more than one application as the Lead Institution.

The goal of the Bridges to the Baccalaureate Research Training Program is to provide structured activities to prepare a diverse cohort of research-oriented students to transfer from associate degree-granting institutions to baccalaureate degree-granting institutions and complete a baccalaureate degree in disciplines related to the biomedical sciences.. This funding opportunity announcement (FOA) provides support to eligible, domestic institutions to develop and implement effective, evidence-informed approaches to biomedical training and mentoring that will keep pace with the rapid evolution of the research enterprise. NIGMS expects that the proposed research training programs will incorporate didactic, research, mentoring, and career development elements. This program requires strong partnerships between at least two post-secondary educational institutions offering science, technology, engineering, or mathematics (STEM) degrees. At least one partner must be an institution that offers the associate degree as the highest STEM degree and the other partner(s) must offer baccalaureate degrees in biomedically relevant STEM fields. Upon completion of the Bridges to the Baccalaureate Research Training program, trainees are expected to be well positioned to pursue research-oriented biomedical higher degree programs or enter careers in the biomedical research workforce.

This Funding Opportunity Announcement (FOA) does not allow appointed Trainees to lead an independent clinical trial, but does allow them to obtain research experience in a clinical trial led by a mentor or co-mentor.