National Institutes of Health (NIH)

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Limiting Language
Number of Applications Only one application per institution (normally identified by having a unique DUNS number or NIH IPF number) is allowed. A single consolidated, application from several institutions within the same Metropolitan Statistical Area, as defined by the Office of Management and Budget (MSA, https://www.whitehouse.gov/omb/information-regulatory-affairs/statistic…) is strongly encouraged and preferred. A MSA consists of the county or counties (or equivalent entities) associated with at least one urbanized area of at least 50,000 population, plus adjacent counties having a high degree of social and economic integration with the core as measured through commuting ties (https://www.census.gov/programs-surveys/metro-micro/about/glossary.html). To assist applicants in determining the boundaries of MSAs, please utilize the delineation files resource at the U.S. Census website (https://www.census.gov/geographies/reference-files/time-series/demo/metro-micro/delineation-files.html) or contact the NIDDK program staff.

Purpose
The Division of Kidney, Urologic, and Hematologic Diseases (KUH) of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) aims to reshape and refocus its Institutional Training Award (T32) program. Compared to the traditional NIDDK/KUH NRSA T32 programs, the program supported by this Notice of Funding Opportunity (NOFO) will have fewer, larger Institutional Network Awards (U2C-TL1). These U2C-TL1 awards will be designed to cultivate a highly integrated cohort of people and resources to propel KUH training and research. The U2C cooperative component will coordinate and provide administrative support for the Institutional Network Award activities, while the TL1 training component will allow the institution to recruit and fund at least 5 highly competitive pre- and/or post-doctoral trainees across K-, U-, and H-mission focused research. With coordinated support from an Administrative Core, each U2C-TL1 Award is expected to:

• Enhance Career Preparation (U2C Professional Development Core). Promote interdisciplinary approaches to prepare trainees for the next step in their scientific careers by exposing them to innovative technologies and critical research resources. Develop tailored and structured educational experiences, including specific training in professional development, leadership, entrepreneurship, and mentorship.
• Increase Networking and Outreach (U2C Networking Core). Coordinate a vibrant and dynamic cohort of K, U, and H trainees, including those supported directly by the TL1 component of this award and those institutional trainees already supported by other NIH training mechanisms, such as Fellowships (Fs), Career Development Awards (Ks), Short-term Training Grants (T35s), and Education Program Grants (R25s). Support a robust mentoring environment, including active peer-to-peer and alumni networks.
• Recruit and Train Interdisciplinary Researchers (TL1 Training Core). Fund highly talented trainees from scientifically broad backgrounds via the TL1 component of this award.

Successful programs will provide an environment that will optimize the ability of trainees to conduct rigorous, ethical research to generate new knowledge, apply interdisciplinary approaches to research questions, and utilize principles of team-science to further their leadership and problem-solving skills. Programs should also support the development of a peer-to-peer network and provide ample career development resources for the community of K, U, and H trainees within the institution. Trainees who complete training under this program are expected to experience a strong, individually tailored, research foundation that permits them to communicate effectively through scientific presentations, compete for additional research support and be prepared to successfully navigate the next steps in a research or scientific career. Resources provided through the U2C activities are expected to accelerate the achievement of these milestones and enhance the establishment of a training community at the awardee institutions.

To foster a true community of trainees, applicant organizations may submit only one Institutional Network Award application. A single, consolidated application from several institutions within the same metropolitan area, that include multiple departments with a different research focus are strongly encouraged. Programs should include trainees across the entire KUH research mission. In other words, trainees may be engaged in benign kidney, urologic, or hematologic research within a single program. Institutional Network Awards applications that engage trainees across all three K-, U-, and H- disciplines are encouraged. While equal representation across these disciplines is not required, NIDDK encourages applicants to leverage available resources -- to the extent possible -- to maximize the training opportunities across K-, U- AND H- research. This may be accomplished by partnering with other departments within a given institution or by partnering with other institutions in the Metropolitan Statistical Area (if feasible). Multi-institutional applications are not required, but they are encouraged if partnership enhances the training environment and experience.

Over time, it is expected that each Institutional Network Award will actively participate in a nationwide program -- formed by the collection of individual KUH U2C-TL1 awards -- to train a cohort of researchers capable of achieving the scientific breakthroughs necessary to improve the care of people with kidney, urologic, and hematologic diseases
 

The University of Arizona is not eligible due to an existing award.

The University of Arizona is not eligible for this funding opportunity

NIGMS will co-fund applications from higher education institutions that award undergraduate (B.S. or B.A.) and/or graduate degrees in biomedical sciences and have received no more than $6 million dollars per year (total costs) from NIH Research Project Grants (RPGs) in each of the preceding two fiscal years, calculated using NIH RePORTER, at the time of the application.  Applications to be considered must support research aligned with the NIGMS mission. Applications for research capacity building in Institutional Development Award (IDeA)-eligible states will be considered.  

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Number of Applications
Applicant organizations may submit more than one application, provided that each application is scientifically distinct, and each is from a different candidate.

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Number of Applications
The NIH will not accept duplicate or highly overlapping applications under review at the same time, per 2.3.7.4 Submission of Resubmission Application. This means that the NIH will not accept:

• A new (A0) application that is submitted before issuance of the summary statement from the review of an overlapping new (A0) or resubmission (A1) application.
• A resubmission (A1) application that is submitted before issuance of the summary statement from the review of the previous new (A0) application.
• An application that has substantial overlap with another application pending appeal of initial peer review (see 2.3.9.4 Similar, Essentially Identical, or Identical Applications).

Two applications per institution (with a Unique Entity Identifier ) and a unique NIH eRA Institutional Profile File (IPF) number) are allowed per review round. The same or a similar topic may be submitted for subsequent review rounds involving the same or a similar team, but must be presented as a New application, not a Resubmission.

Applications that are not considered to be within the NIGMS mission will not be reviewed. Eligibility and appropriateness to the NIGMS mission will be evaluated again after review and prior to funding. Applications outside the NIGMS mission will not be funded. Given that only two applications are permitted per institution per review round, it is important to contact NIGMS staff before committing to any particular team and its topic area.

Purpose: 
This Funding Opportunity Announcement (FOA) is designed to support highly integrated research teams of three to six Program Directors/Principal Investigators (PDs/PIs) to address ambitious and challenging research questions that are within the mission of NIGMS. Project goals should not be achievable with a collection of individual efforts or projects. Collaborative program teams are expected to accomplish goals that require considerable synergy and managed team interactions. Teams are encouraged to consider far-reaching objectives that will produce major advances in their fields.

This FOA is not intended for applications that are mainly focused on the creation, expansion, and/or maintenance of community resources, creation of new technologies, or infrastructure development.

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This Funding Opportunity Announcement (FOA) invites applications from institutions proposing to establish, or renew, an Alzheimer's Disease Research Center (ADRC).

NIA-designated ADRCs serve as a national resource for research on the nature of Alzheimer’s disease (AD) and AD-related dementias (ADRD) and the development of more effective approaches to prevention, diagnosis, care, and therapy. They create shared resources that support dementia-relevant research, and they collaborate and coordinate their research efforts with other NIH-funded programs and investigators.

Institutionally Coordinated

ORIP's S10 Instrumentation Grant Programs support purchases of state-of-the-art commercially available instruments to enhance research of NIH-funded investigators. Instruments that are awarded are typically too expensive to be obtained by an individual investigator with a research project grant. Every instrument awarded by an S10 grant is to be used on a shared basis, which makes the programs cost-efficient and beneficial to thousands of investigators in hundreds of institutions nationwide.

To be eligible for an S10 award, an institution must identify three or more principal investigators with active NIH research awards who demonstrate a substantial need for the requested instrument. Matching funds are not required. Types of instruments supported by S10 funding include, but are not limited to, X-ray diffraction systems, nuclear magnetic resonance (NMR) and mass spectrometers, DNA and protein sequencers, biosensors, electron and confocal microscopes, cell-analyzers, and biomedical imagers.

Active RFPs are: 

• Basic Instrumentation Grant Program (BIG) – University of Arizona is not eligible 
• Shared Instrumentation Grant Program (SIG) – The SIG Program funds grant awards in the $50,000 to $600,000 range.
• High-End Instrumentation Grant Program (HEI) – The HEI Program funds grant awards in the $600,001 to $2,000,000 range.

There is no restriction on the number of applications an institution can submit to the SIG and/or High-End HEI Grant Programs. However, institutional internal coordination is required for concurrent SIG or HEI applications to verify each proposal is requesting different types of equipment.

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D. Bhattacharya 

NIH recognizes that modern physical infrastructure is necessary for the conduct of cutting-edge research or support specialized breeding operation. Dedicated space is required to house specialized equipment and to carry out experimental protocols. Equipment that enables automation and husbandry of the breeding facility, enhances modern operation, allows telemetry for field/corral monitoring, facilitates social behavioral interactions may be eligible under this NOFO. The scope of individual applications will vary and depend on the currently available infrastructure at the applicant institution, as well as the present and anticipated HIV/AIDS research needs. Requests must be justified by the needs for expanding the breeding capacity for support of HIV/AIDS research. The project, when completed, is expected to provide significant long-term cost-effective support for HIV/AIDS research, bringing the capacities and capabilities to a new level. Consequently, the applicant institution should demonstrate future-looking commitments towards the facility and HIV/AIDS research therein, by attaching a letter of support from a high-ranking institutional official.

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The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The overarching goal of this R25 program is to support educational activities that encourage individuals from diverse backgrounds, including those from groups underrepresented in the biomedical and behavioral sciences, to pursue further studies or careers in research.

To accomplish the stated over-arching goal, this NOFO will support educational activities with a primary focus on:

• Courses for Skills Development
• Research Experiences
• Mentoring Activities

The fully integrated educational activities should prepare undergraduate students from diverse backgrounds, including those from groups underrepresented in biomedical and behavioral sciences, to enter Ph.D. degree programs in the neurosciences. To accomplish this goal, this initiative will provide institutional awards to develop neuroscience research education programs comprised of collaborative partnerships integrated across different educational institution types.

Each partnership must include:
a) one or more institutions that either: 1) have a historical and current mission to educate students from any of the populations that have been identified as underrepresented in biomedical research as defined by the National Science Foundation (NSF), see http://www.nsf.gov/statistics/wmpd/) (i.e., African Americans or Blacks, Hispanic or Latino Americans, American Indians, Alaska Natives, Native Hawaiians, U.S. Pacific Islanders, and persons with disabilities) or 2) have a documented track record of recruiting, training and/or educating, and graduating underrepresented students as defined by NSF (see above), which has resulted in a historically documented contribution by the institution to the national pool of graduates from underrepresented backgrounds who pursue biomedical research careers;
b) a research-intensive institution that has an established neuroscience or neuroscience-related program;
c) integrated curriculum/academic enhancement and research experience activities designed to increase participants' preparation to enter doctoral programs in the neurosciences; and
d) well-described plans to provide early communication and interaction between participating students and graduate neuroscience programs across the country.

Components of Participating Organizations:
National Institute of Neurological Disorders and Stroke (NINDS)
National Eye Institute (NEI)
National Institute on Aging (NIA)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
National Institute on Deafness and Other Communication Disorders (NIDCD)
National Institute of Dental and Craniofacial Research (NIDCR)
National Institute on Drug Abuse (NIDA)
National Institute of Environmental Health Sciences (NIEHS)
National Institute of Mental Health (NIMH)
National Center for Complementary and Integrative Health (NCCIH)
All applications to this funding opportunity announcement should fall within the mission of the Institutes/Centers. The following NIH Offices may co-fund applications assigned to those Institutes/Centers.
Office of Behavioral and Social Sciences Research (OBSSR)

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NIGMS will accept only one application per eligible organization.

The goal of the Bridges to the Doctorate Research Training Program is to develop a diverse pool of scientists earning a Ph.D. who have the skills to successfully transition into careers in the biomedical research workforce. This funding opportunity announcement (FOA) provides support to eligible, domestic institutions to develop and implement effective, evidence-informed approaches to biomedical training and mentoring that will keep pace with the rapid evolution of the research enterprise. NIGMS expects that the proposed research training programs will incorporate didactic, research, mentoring, and career development elements to prepare trainees for careers that will have a significant impact on the health-related research needs of the Nation.

This FOA does not allow appointed trainees to lead an independent clinical trial but does allow them to obtain research experience in a clinical trial led by a mentor or co-mentor.