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Centers for Disease Control and Prevention (CDC)

CDC RFA-IP-24-045: 2024 Network of Community Cohorts for Monitoring Changes in Respiratory Virus Epidemiology (Pandemic Preparedness Cohorts)

 Limit: 1 // K. Lutrick (Research, Family & Community Medicine) & K. Ellingson (Epidemiology and Biostatistics)

 

Only one application per institution (normally identified by having a unique entity identifier [UEI] number) is allowed. 

The purpose of this Notice of Funding Opportunity (NOFO) is to establish: 1) a multi-site community-based cohort study that would allow close monitoring of the burden of acute respiratory illness in the community, contributions of various respiratory viruses to this burden, and the impact of vaccination and other interventions on risk of infection and/or severe outcomes, and 2) a case-ascertained household transmission study (or multi-site study) that would support ongoing assessment of transmission dynamics of respiratory viruses of interest and factors (i.e., demographic, clinical, or household-level factors) that may impact transmission.

While hospital-based platforms are key to assessing frequency and risk factors for severe disease, community-based platforms are essential for understanding age-specific incidences of infection, risk factors for infection, socioeconomic burden of infections (such as days of work/school lost), and the clinical spectrum of illness. They are important for characterizing the immune response to infection or reinfection and long-term outcomes, and they are key to understanding the impact of individual- and household-level mitigation factors (including but not limited to vaccination) on all of these measures. This type of network may be especially useful for detecting changes in any of these factors when a new virus or viral variant begins circulating.

Case-ascertained household transmission studies are well-positioned to quickly and efficiently enable us to understand transmission dynamics of respiratory viruses (or sublineages/types of existing viruses that undergo frequent mutation, such as SARS-CoV-2 and influenza) and assess potential mitigation factors. These studies can also be valuable for characterizing viral shedding dynamics and infectiousness. These studies were key during the COVID-19 pandemic to understanding if changes in hospitalization rates were due to changes in transmissibility/infection rates versus changes in severity of illness. They are also great resources for assessing how history of vaccination or prior history of infection effect transmission to close contacts.

This NOFO would build on the lessons learned during the COVID-19 pandemic and establish a consolidated network of community cohorts to monitor a range of respiratory viruses among community members who develop symptoms of acute respiratory illness. Incorporation of multi-pathogen testing will allow us to better understand the relative contribution of various viruses to the overall community burden of respiratory disease now in the post-pandemic setting, and how the clinical spectrum of these illnesses compare, in a setting in which multiple new preventive products are becoming available. This would also support the establishment of a case-ascertained transmission study (or multi-site study) that would be able to assess SARS-CoV-2, Respiratory Syncytial Virus (RSV), and other prioritized respiratory viruses on an ongoing basis.

The combination of these studies will generate much greater visibility on risk factors for infection and the effectiveness of various interventions in reducing infections and viral transmission, factors that are relevant to reducing overall morbidity and mortality related to respiratory viruses. Should a new variant or virus arrive, this platform would be well positioned to further expand testing to better understand potential concerns like proportion symptomatic, timing of transmission, likelihood of asymptomatic transmission and other related questions. Such questions may be key to developing public health guidance should additional mitigation measures become necessary.

 

Funding Type
External Deadline
02/20/2024
Internal Deadline

CDC RFA-DP-24-138: 2024 Demonstration Projects to Research and Evaluate Strategies Aligned with CDC’s What Works in Schools Approach

No Applicants // Limit: 1 // Tickets Available: 1 

 

Only one application per institution (normally identified by having a unique UEI number) is allowed.

This Notice of Funding Opportunity (NOFO) supports research to implement and evaluate strategies aligned with CDC’s What Works in Schools (WWIS) approach for successful implementation in local education agencies and schools serving rural or American Indian and/or Alaska Native (AI/AN) adolescents to address students’ health behaviors, experiences, and outcomes, particularly those related to sexual and reproductive health and mental and behavioral health, as well as suicidality, substance use, and experiences of violence. The purpose of the research is to build the evidence base for innovative, school-based or school-linked strategies that promote the health of youth across multiple health domains while also supporting translation and dissemination of the research findings. Strategies may include programs, policies, or practices that seek to improve sexual and reproductive health as well as improve mental and behavioral health in a manner that also addresses health equity among youth in local education agencies and schools serving rural or AI/AN adolescents. Additionally, strategies may also seek to reduce suicidality, substance use and experiences of violence among school-aged adolescents.

 

The estimated total funding (direct and indirect) for the first year (12-month budget period) will be $1,000,000.00 with individual awards of $500,000.00 each for two awards. The estimated total funding (direct and indirect) for the entire project period will be $5,000,000.00. The project period is anticipated to run from 09/29/2024 to 09/28/2029.

Funding Type
External Deadline
3/11/2024
Internal Deadline

CDC RFA-DP-24-081: 2024 Effectiveness of Telehealth-Based Programs to Detect Glaucoma Among High-Risk Populations in Community Health Settings

No applicants // Limit: 1 // Tickets Available: 1

 

Only one application per institution (normally identified by its UEI number) is allowed.

The purpose of this NOFO is to support comparative effectiveness trials to investigate the feasibility, effectiveness, and cost-effectiveness of telehealth-based interventions to detect and manage glaucoma among high-risk populations. This NOFO aims to support the study of replicable and scalable interventions that use real-world, payer-provider reimbursement structures within community-based, health care delivery settings in various regions of the United States. Outcomes should be relevant to clinical practice, public health, community implementation, and policy. This NOFO also supports the cost-effectiveness analyses of proposed interventions. The resulting data will assist policymakers, clinicians, and patients make informed decisions to reduce the burden of glaucoma and improve the quality of life for millions of people.

This NOFO will be accomplished through two components, Component A: Comparative effectiveness trials among high-risk populations within community-based settings, and Component B: a coordinating center to provide scientific and logistical support to Component A studies. 

Component A: Number of Awards: four (4); Estimated Funding: $2,750,000
Component B: Coordinating Center Number of Awards: One (1); Estimated Funding: $250,000

External Deadline
02/05/2024 - Letter of Intent (LOI)
Internal Deadline

CDC RFA-PS-24-042: A Bridge to Adherence: Long-Acting Antiretroviral Therapy for People with HIV Released from Prison

No Applicants // Limit: 1 // Tickets Available: 1

 

Only one application per institution (normally identified by having a unique entity identifier [UEI] number) is allowed. 

This Notice of Funding Opportunity (NOFO) is designed to understand the feasibility and acceptability of providing long-acting injectable antiretroviral therapy (LAI-ART) to incarcerated persons with HIV who are soon to be released from state prison facilities. The ultimate goal is to support the development and implementation of effective, sustainable, replicable LAI-ART programs. People with HIV living in prison facilities are often released to the community lacking support for ongoing HIV care. There is a paucity of programs for this population demonstrating effectiveness with retention in care and maintaining sustained HIV viral suppression after release. The use of LAI-ART prior to and at the time of release from prison may improve adherence to HIV treatment, retention in care, and maintenance of viral load suppression among persons reentering the community. Applied qualitative and quantitative research resulting from this funding is expected to strengthen adherence to ART and is aligned with the HIV National Strategic Plan (2022-2025) and the Ending the HIV Epidemic in the U.S. (EHE) initiative “Treat” Pillar.

External Deadline
03/01/2024
Internal Deadline

CDC RFA-DP-24-031: 2024 Epidemiologic Cohort Study of Interstitial Cystitis

No Applicants // Limit: 1 // Tickets Available: 1 

 

The purpose of this research NOFO is to follow a cohort of interstitial cystitis (IC) patients over time, define the demographic and clinical patterns of IC, and document its impact on the health of affected people. In addition, the focus of this NOFO will include translating the scientific knowledge on IC extracted from previously funded and other studies so it can be used to support public health action, including patient strategies for improving quality of life, provider awareness and education, and medical and self-management of IC; strengthen clinical, community, and public health linkages; and target groups disproportionately impacted by IC.

 

The estimated total funding (direct and indirect) for the first budget period (9/30/2024 to 9/29/2025) is $830,000. The estimated total funding (direct and indirect) for the entire performance period (9/30/2024 to 9/29/2029) is $4,150,000. The estimated award ceiling is $900,000 for the first 12-month budget period (9/30/2024 to 9/29/2025).

Funding Type
External Deadline
02/09/2024
Internal Deadline

CDC RFA-OH-24-001: 2023 National Center for Construction Safety and Health Research and Translation (U54)

No applicants // Limit: 1 // Tickets Available: 1 


Only one application per institution is allowed.

NIOSH is seeking applications from qualified organizations for a National Center for Construction Safety and Health Research and Translation (also known as the NIOSH National Construction Center). Applicants areexpected to propose multi-disciplinary approaches for impactful applied and intervention research and hazard identification and controls, to develop partnerships for implementing prevention and intervention activities, and to serve as leaders in research translation and research-to-practice for the protection of construction workers in the United States. The NIOSH National Construction Center will accomplish these goals by 1) integrating and advancing research, 2) translating and disseminating best practices, 3) disseminating information, 4) informing policy, and 5) building capacity. Applicants must describe the occupational health and safety burden(s) addressed in their proposals. In addition, they must link the need for the proposed research and related activities to the planned outputs and outcomes that will help address or alleviate the construction sector burdens described. Applicants should also describe the anticipated impacts and potential outcomes of the proposed research and related activities that will occur during the 5-year project period and beyond.

Funding Type
External Deadline
11/01/2023
Internal Deadline

CDC RFA-DP-24-004: 2023 Health Promotion and Disease Prevention Research Centers

S. Carvajal (Health Promotion Sciences)

This Notice of Funding Opportunity (NOFO) will provide funding to academic research centers to participate in the network of Health Promotion and Disease Prevention Research Centers (PRC Network) to:Establish and maintain a multi-disciplinary prevention research center (Center) that conducts high-quality applied health promotion and disease prevention public health research (hereafter referred to as prevention research); Conduct one (1) dissemination and implementation (D&I) core research project that utilizes (a) an evidence-based public health intervention (EBI) and (b) an equitable and evidence-based community engaged approach – e.g., community-based participatory research (CBPR), to address a leading cause of chronic disease morbidity or mortality in a population experiencing high levels of health disparities or health inequities;Collaborate with partners that can help translate research findings into practice within the research community (hereafter referred to as partners that translate), promote sustainability beyond the core research project, and facilitate dissemination;Disseminate research findings to community, practice, and academic audiences; Serve as a resource to other PRCs, as part of the PRC Network, for adapting, implementing, evaluating, disseminating, and translating evidence-based public health interventions at local, state, tribal, or national levels; andParticipate in the PRC Network to (a) leverage the expertise of the network members to inform individual core research project and center activities (as needed) and (b) advance the network’s collective impact in public health prevention research, policy, and practice.

Funding Type
External Deadline
06/23/2023
Internal Deadline

CDC CDC-RFA-DP-23-0020: 2023 A Strategic Approach to Advancing Health Equity for Priority Populations with or at Risk for Diabetes

No applicants // Limit: 1 // Tickets Available: 1 


The NOFO contains 3 components: A, B, and C. UA may apply for only 1 component.


This NOFO seeks to decrease risk for type 2 diabetes among adults with prediabetes and improve self-care practices, quality of care, and early detection of complications among people with diabetes. Additionally, this NOFO will support implementation of evidence-based, family-centered childhood obesity interventions as a type 2 diabetes risk reduction strategy. The NOFO includes 3 components. Applicants may apply for only 1. Components A and B focus on a menu of strategies to decrease risk for type 2 diabetes among adults at high risk; improve selfcare practices, quality of care, and early detection of complications among priority populations with diabetes; and support implementation of family-centered childhood obesity interventions to reduce risk for type 2 diabetes. Component A will fund 51 organizations physically located in each of the 50 states and the District of Columbia to achieve state/district-wide reach. Component B will fund up to 22 organizations to work in US counties identified as “high need” based on diabetes burden and social vulnerability; applicants’ work must reach a population > 350,000 across one or more of these counties, in partnership with local organizations. Component C will fund 3-4 multisectoral partnership networks to simultaneously and collaboratively address 4 aspects of work proven necessary to scale and sustain the National Diabetes Prevention Program to better engage, enroll, and retain large numbers of participants. 

Funding Type
External Deadline
01/20/2023
Internal Deadline