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Centers for Disease Control and Prevention (CDC)

Reducing the burden of parasitic infections in the United States through evidence-based prevention and control activities

Request Ticket // Limit: 1 // Tickets Available: 1

Limiting Language 
Under this NOFO, you may submit only one application under your organization’s Unique Entity Identifier (UEI).

Summary 
The purpose of this Notice of Funding Opportunity (NOFO) is to decrease the impact of specific parasitic infections in the U.S. with public health practices and disease control strategies. The NOFO focuses on three parasitic infection areas: 
• Chagas disease.
• Soil-transmitted helminths. 
• Other parasitic diseases of domestic concern in the U.S. 

This NOFO will continue CDC’s Parasitic Disease Branch work to help healthcare providers (HCPs) better understand, detect, treat, and prevent parasitic infections. Improved understanding and management of parasitic diseases in the U.S. will help make Americans stronger, safer, and more prosperous. There are three components of this NOFO. You may apply for only one: 
• Component A will improve HCPs’ knowledge and practices. Increase testing and management of people with or at risk of Chagas disease. Expand the use of best practices, training tools, and materials. 
• Component B will strengthen public health efforts to monitor and control soil-transmitted helminth infections (like hookworm). It focuses on areas in the Southeastern U.S. (as defined by the U.S. Census Bureau) that are historically affected. 
• Component C will target the prevention, control, health education, and, where applicable, elimination of other parasitic diseases in the U.S. Diseases include cyclosporiasis, cysticercosis, echinococcosis, leishmaniasis, lymphatic filariasis, and toxoplasmosis.

We will not accept proposals focused on malaria, amoebiasis,cryptosporidiosis, giardiasis, or any international activities. Your strategies should aim for significant public health benefits and reach a large portion of at-risk populations.

Funding Type
External Deadline
7/17/2026

Preventing global health threats by strengthening surveillance systems to accelerate outbreak detection, notification, and response

Request Ticket // Limit: 1 // Tickets Available: 1

Limiting Language 
Under this NOFO, you may submit only one application under your organization’s UEI.

Summary
This NOFO focuses on protecting Americans from global health threats across three strategic areas: • Strengthening Early Warning Surveillance. 
• Developing or enhancing electronic tools and interoperable surveillance systems. 
• Improving how surveillance data is used for action. 

This NOFO will support global health security partners to implement surveillance activities that speed up outbreak detection and response, enhance regional and national health system capacities, and strengthen and expand global health partnerships.

Required Delivery Location
 You must conduct the project in these focused regions and countries: 
• Central and South America: Guatemala, Colombia, Ecuador, Peru. 
• East Africa: Ethiopia, Kenya, Tanzania, Uganda. • Eastern Europe/Central Asia: Armenia, Georgia, Kazakhstan, Ukraine. 
• Middle East: Pakistan, Jordan, Egypt. 
• South and Southeast Asia: Bangladesh, India, Cambodia, Indonesia, Thailand, Vietnam. 
• Central and Southern Africa: Cameroon, Dem. Rep. Congo, Mozambique, South Africa, Zambia. 
• West Africa: Burkina Faso, Cote d’Ivoire, Ghana, Guinea, Liberia, Mali, Nigeria, Senegal, Sierra Leone. 
You may propose additional related strategies and activities to achieve the expected outcomes. You may also submit an application supporting activities in any country but are encouraged to submit a proposal that covers at least three of the stated regions and/or countries.

 

Funding Type
External Deadline
7/15/2026

Building National Partnerships for the Prevention of Emerging and Reemerging Infectious Diseases

No Applicants // Limit: 1 // Tickets Available: 1

Limiting Language 
Under this NOFO, you may submit only one application under your organization’s UEI.

Summary
This notice of funding opportunity (NOFO) strengthens the United States’s capacity to prevent, detect, and respond to infectious disease threats. It improves infrastructure, workforce development, risk and health messaging, and emergency response capabilities. It will help:

  • Expand training for infection prevention and control (IPC) and combating antimicrobial resistance (AR). 
  • Enhance engagement of frontline healthcare and public health workers. 
  • Improve healthcare facility resilience. 
  • Improve coordination and surge staffing during public health responses.
Funding Type
External Deadline
7/1/2026

Enhancing global laboratory systems to safely manage biological risks, deploy diagnostics, and sequence pathogens to improve capacities for global health threat response and detection

Request Ticket // Limit: 1 // Tickets Available: 1

Please see the NOFO for required delivery locations where proposed projects must be conducted.

Limiting Language
Under this NOFO, you may submit only one application under your organization’s UEI.

Summary
This NOFO aims to protect Americans from global health threats by focusing on five strategic areas:

  • Strengthening public health laboratory systems and services across multiple levels to help create a cohesive network that supports robust public health initiatives.
  • Making sure there’s consistent and reliable access to high-quality services around the world by improving essential laboratory quality management systems.
  • Building a resilient and well-trained workforce, equipped with the skills to meet evolving health challenges.
  • Identifying and managing biological risks to make sure public health laboratory operations are safe and reliable.
  •  Reinforcing laboratory preparedness so that Americans can be protected from widespread health threats by making sure that outbreak response is fast and effective.
Funding Type
External Deadline
7/13/2026

Eliminating Parasitic and Neglected Tropical Disease Threats to the United States – Program Support and Research to Reduce Threats to Americans at Home and Abroad

No Applicants // Limit: 1 // Tickets Available: 1

Limiting Language
You may submit only one application per institution. This is normally identified by having a Unique Entity Identifier (UEI) number.

Summary 
The purpose of this notice of funding opportunity (NOFO) is to expand the network of institutes working with CDC to help eliminate or control non- malaria parasitic threats and neglected tropical diseases (NTDs). This NOFO will focus on threats and diseases that may affect Americans at home or abroad or whose elimination or control would serve other U.S. priorities.

This program will also support research that will provide tools and information to improve NTD and parasitic disease program activities. The program will also integrate evaluation and surveillance activities for multiple NTDs and other parasitic diseases.

Funding Type
External Deadline
7/6/2026

Increasing awareness and knowledge of Alpha-gal Syndrome in the United States

No Applicants // Limit: 1 // Tickets Available: 1 

Summary 

This NOFO’s aim is to improve awareness and knowledge of alpha-gal syndrome (AGS) in the United States. AGS is an emerging condition and is not nationally notifiable. This will happen through:

  • The creation of a professional network of AGS researchers and public health professionals.
  • Improved surveillance.
  • Improved communications materials.

This NOFO seeks to improve:

  • AGS surveillance.
  • Patient care.
  • Awareness and understanding.
     

The NOFO’s three main strategies are to:

  • Share: Disseminate the latest knowledge about AGS among stakeholders to improve patient care for AGS and the public health response.
    • This includes public health agencies, academic researchers, and
      advocacy groups.
  • Track: Conduct active or enhanced surveillance for AGS.
    • This strategy could involve patient populations or geographic locations with limited access to specialized healthcare provider care.
  • Educate: Create AGS communications targeted at the general public, AGS patients, and/or people at higher risk for tick encounters (outdoor enthusiasts, dog owners, etc.).
    • Communications targeted at healthcare providers, healthcare provider educational resources, and training would also fall under this strategy.
Funding Type
External Deadline
6/19/2026

Drug-Free Communities Support Program: NEW (Year 1 – FY25 Cohort)

No Applicants // Limit: 1 // Tickets Available: 1

Limiting Language
Under this NOFO, you may submit only one application under your organization’s Unique Entity Identifier (UEI).

Summary
The purpose of this NOFO is to support community coalitions that work to
prevent and reduce substance use among youth. This NOFO aligns with the
Drug-Free Communities (DFC)’s Support Program’s two goals:
• Establish and strengthen collaboration among community stakeholders
and organizations to address youth substance use.
• Reduce substance use among youth and, over time, reduce substance
use among adults by:
◦ Addressing the factors in a community that increase the risk of
substance use.
◦ Promoting the factors that minimize the risk of substance use.

The DFC program will fund coalitions that haven’t received DFC funding.

Please note: The DFC Program is funded and administered by the White
House Office of National Drug Control Policy (ONDCP). CDC manages the DFC
Program on behalf of ONDCP.
 

Research Category
Funding Type
Internal Deadline
External Deadline
2/12/2026

Health Promotion and Disease Prevention Research Centers: 2025 Special Interest Project Competitive Supplements (SIPS)

Limit: 1 per SIP

K. Ellingson (Public Health) for SIP25-005 Understanding the potential of early childcare and education (ECE) centers in promoting childhood vaccines and RSV prevention products

S. Carvajal (College of Public Health's Prevention Research Center) for SIP25-006 Overdose Prevention and Treatment Research Network (OPTRN)

Eligibility: 
Only one application per SIP per institution is allowed (e.g., multiple applications for the same SIP (listed in Section VIII) from the same institution are NOT permitted).

Purpose:
This Notice of Funding Opportunity (NOFO) invites applications from CDC Health Promotion and Disease Prevention Research Centers (PRCs), selected for funding under RFA-DP-24-004, to apply for supplemental funding to conduct Special Interest Research Projects (SIPs) to inform public health practice. PRCs will conduct high-quality applied health promotion and disease prevention research projects in real-world settings to identify, design, test, evaluate, disseminate, and translate interventions (i.e., programs, practices, policies, or strategies) to prevent and reduce risk for the leading causes of illness, disability, and death in the United States.

Funding Type
Internal Deadline
External Deadline
2/28/2025

CDC RFA-OH-22-002: 2024 Centers for Agricultural Safety and Health (U54)

No Applicants  // Limit: 1 // Tickets Available: 1 

 

The National Institute for Occupational Safety and Health (NIOSH) within the Centers for Disease Control and Prevention (CDC) invites applications for the Centers for Agricultural Safety and Health (Ag Centers). These centers are expected to conduct high quality research and subsequently disseminate their findings and recommendations in audience appropriate products to contribute to improving the safety and health of agriculture, forestry, and fishing workers. Center structure should take advantage of diverse scientific resources and focus on local, regional, and/or national worker safety and health issues. Emphasis should be placed on the creation and implementation of evidence-based solutions that address important agricultural, forestry, and fishing safety and health problems. Centers should also use innovative approaches to identifying, understanding, and developing strategies for overcoming barriers to the adoption, adaptation, integration, scale-up and sustainability of evidence-based solutions. Collaborations with other academic institutions, nonprofit organizations, and other occupational safety and health focused groups are expected. Applicants must concisely describe the occupational safety and health burden within their service area and directly link research and outreach activities to help alleviate the burden. Applicants should also clearly articulate the anticipated impacts of the proposed work, both during the project period and beyond.

 

Ag Center Structure

NIOSH Ag Centers provide interdisciplinary research and outreach efforts to address AgFF-related occupational health and safety problems. Applicants should keep in mind the required and optional components essential to Ag Center function, detailed below, in providing an overall description of the proposed Ag Center, addressing 1) the burden of occupational injuries and illnesses within their region for this work sector, 2) the regional and national need for the Ag Center’s proposed programs and projects, and 3) the Center’s impact, or potential for impact, on AgFF worker health and safety.

The following required components enable Ag Centers to cohesively address their goals and objectives for providing impact:

Evaluation and Planning Core. The purpose of the Evaluation and Planning Core is to 1) provide oversight, leadership, and management for the Center, including establishment and maintenance of advisory committees; 2) engage in long-range planning, coordination, and implementation of work that crosses multiple cores, programs or projects; and 3) develop and assist in implementing evaluation efforts at the Center, core, program and project levels. Any collaborative projects with other Ag Centers should include the Evaluation and Planning Core for the purposes of oversight and coordination.

Outreach Core. The purpose of the Outreach Core is to ensure that evidence-based approaches, technologies, guidelines, policies, best practices, or similar activities are promoted and implemented in affected populations to benefit workers and their associated work environments. Much of the work in the Outreach Core will be implemented through partnerships and collaborations with nonprofit organizations, community groups, industry groups, employers, or similar entities.

Research Core. The purpose of the Research Core is to develop programs and projects in response to the goals identified in the Center's strategic plan and subsequently manage, monitor, and coordinate this work within the Center. Research activities include basic/etiologic, intervention, translation, and surveillance. Activities can vary widely, from pilot or feasibility studies that are minimally resourced and may be exploratory in nature to large, R01-like projects that require preliminary data and significant investment in personnel, equipment, time, and space. The Research Core is comprised of the required research projects and the optional Pilot/Feasibility Program Please note, the "Research Core" is not an actual component within the application - instead it is a construct to address budget limits across multiple and varied activities (i.e., required research projects and the optional pilot/feasibility program). There is no limitation to the number of research projects that applicants can propose as long as they stay within the annual direct costs requirements.

 

Objectives/Outcomes

The primary goal of an Ag Center is to conduct high quality scientific research and outreach efforts to address local, regional, and national AgFF problems. This will ultimately be accomplished through the goals in the Center’s Strategic Plan. However, the operational process for accomplishing these goals should not be overlooked and therefore, each core, program and project should develop operational objectives to support the goals in the Plan.

Target Population

There are many affected subpopulations in AgFF professions. The attributes of these affected subpopulations (such as demographics, size, risks/hazards encountered, and resources available to educate or assist in addressing the problem) will drive the proposed projects and their anticipated outputs and impacts. Ag Centers are distributed throughout the nation to be responsive to safety and health issues unique to different regions of the country. The risks inherent to an AgFF job are often dependent on the work environment, local/industry work practices, and specific job tasks. Therefore, Ag Centers should clearly describe the specific target populations they are focusing their efforts on and provide information to support the need for these proposed efforts.

 

Industry Sectors, Health and Safety Cross-sectors, and Goals

In the Project Description/Abstract of the application, state which industry sector(s) and health and safety cross-sector(s) the proposed work will address. Provide a clear rationale for how the intended outcomes of the proposed project will contribute to the specified goals in NIOSH's Strategic Plan and, in particular, those identified in the NIOSH Priority Goals for Extramural Research.

Diversity, Equity and Inclusion

In June 2019, NIOSH began an initiative to take substantive action in creating greater diversity, equity, and inclusion in its workforce, the workplace and in its service to the public. This initiative led to the establishment of the NIOSH Diversity and Inclusion Office. The associated strategic plan is intended to guide actions that specifically address diversity, equity and inclusion (DEI) in all aspects of NIOSH's work, including NIOSH-supported extramural programs. Ag Centers should demonstrate a commitment to DEI in all aspects of their center. This commitment should be reflected in the center's core values, mission and outputs.

Asymmetrical power relationships along social axes such as age, class, gender, nativity, and race/ethnicity not only result in social, economic, and environmental disadvantages that impact the distribution of work-related benefits and risks but also result in exclusionary research practices. Developing inclusive research practices, and the institutional capacity to effectively produce data driven solutions that reduce these avoidable inequities, is essential to ensuring the well-being of the increasingly diverse AgFF workforce.

Applicants should describe how they propose to ensure inclusive governance and practice in the required center components (Evaluation and Planning, Outreach, and Research). Discussion should include, but not be limited to, how historically underrepresented groups will be included in agenda setting for the work of the center. For example, this may include participation on advisory boards, as researchers/staff and through partnerships. Applicants should also identify how the center will ensure that research questions, data collection methods and analysis, and dissemination of results will be inclusive of the diversity in the AgFF workforce, especially those from historically underrepresented groups. Applicants should demonstrate how the design, content, format, and dissemination of outreach efforts will be tailored to the needs of workers from diverse backgrounds.

Collaboration/Partnerships

Ag Centers must demonstrate collaborative efforts by working with a diverse and broad range of organizations to enhance worker safety and health in their region. Possible collaborators include universities, labor and professional associations, nonprofit organizations, businesses, and federal, state, or local public health and regulatory agencies. Centers should seek to address a wide range of occupational safety and health concerns in their region, as determined by the burdens posed by these problems or hazards, and their funding applications must describe how their efforts will alleviate or eliminate these burdens.

Evaluation/Performance Measurement

All Center activities should be managed and coordinated as part of the Evaluation and Planning Core. This core is responsible for all new and ongoing center-wide evaluation activities as well as supporting program and project level evaluation efforts. These activities should all be described in a Center evaluation plan. Ag Centers are also strongly encouraged to interact with each other on evaluation methods and best practices, to increase awareness of activities and evaluation techniques. Similarly, centers will work with each other and NIOSH during the performance period to develop shared logic models on common AgFF health and safety outcomes. In addition to center-specific evaluation and performance measurement, Ag Centers may be asked to participate in NIOSH evaluation efforts related to the NIOSH AgFF Program and the NIOSH Evaluation Capacity Building Plan.

Translation Plan

The transfer of evidence-based approaches to intermediaries such as unions, manufacturers, worker groups and end users (employers and workers) through training, conferences, community gatherings, social media, blogs, websites and infographics, peer-reviewed and lay publications, etc. is an essential function of the Outreach Core. While research strengthens our understanding of the determinants of injury, illness, and death, the potential for impact of research findings is found when paired with pragmatic approaches to move findings into practice.

 

  1. Evaluation and Planning Core
  2. Outreach Core
  3. Research Projects (collectively, the "Research Core", along with the optional Pilot/Feasibility Program)
Funding Type
Internal Deadline
External Deadline
09/22/2024 (Required Letter of Intent) - 10/22/2024 ( Full Proposal)

CDC CDC-RFA-TU-24-0142: 2024 Regional Centers for Public Health Preparedness and Response

Limit: 1 //  J. Burgess (Community, Environment & Policy)

 

 

Your organization may submit only one application under this announcement.

The purpose of the NOFO is to establish and maintain a network of Regional Centers for Public Health Preparedness and Response to increase implementation of evidence-based strategies and interventions (EBSIs) and to improve public health preparedness and response, as informed by the needs of the communities involved. Support will be provided for up to ten centers to determine and support implementation of activities needed to increase use of EBSIs that will improve public health preparedness and response, as informed by the needs of the communities as described in regional workplans. The goal is to fund one center in each of the 10 HHS Regions. Each center will1) Coordinate relevant activities with applicable State, local, and Tribal health departments and officials, health care facilities, and health care coalitions to improve public health preparedness and response, as informed by the needs of the community, or communities involved.2) Develop and implement activities to support focus areas and objectives created by a regional coordinating body in 2023-24.3) As determined necessary by the CDC, and based on the availability of funding, support further implementation of evidence-based practices, or conduct research, evaluation, translation or dissemination necessary to address active or anticipated public health emergencies.4) One center will be awarded additional funds to support coordination and convening of centers and provide technical assistance and training as needed.

Funding Type
Internal Deadline
External Deadline
05/21/2024