Centers for Disease Control and Prevention (CDC)

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Limiting Language 
Under this NOFO, you may submit only one application under your organization’s UEI.

Summary 
This Notice of Funding Opportunity (NOFO) supports strengthening country systems to detect, notify, and respond to outbreaks by applying time-bound, evidence-based frameworks, such as the 7-1-7 target, which aims to detect outbreaks within 7 days, notify within 1 day, and respond within 7 days. This target was selected to promote rapid containment and minimize health and economic impacts. 

Activities under this award will be conducted outside the United States and its territories. Building on previous outbreak experience and other international health emergencies, this NOFO advances American interests by reinforcing systems that protect both the United States and recipient nations. 

Activities focus on improving early detection of biological threats, timely notification across sectors and borders, and effective response to contain outbreaks before they spread, consistent with the Detect, Notify, Respond (D- N-R) framework. Efforts include strengthening surveillance, expanding laboratory readiness, enhancing information flows, and improving response operations to reduce economic effects and improve health. These activities emphasize burden sharing, accountability, and efficiency to ensure benefits to Americans at home and abroad, while helping recipient nations achieve long-term self-reliance and stability.

Please see NOFO for required delivery locations. 

Request Ticket // Limit: 1 // Tickets Available: 1 

Limiting Language 
Under this NOFO, you may submit only one application under your organization’s UEI.

Summary 
This notice of funding opportunity (NOFO) will enhance capacity to contain outbreaks through partnerships with Ministries of Health (MOHs), external stakeholders, and other governmental institutions. This NOFO prioritizes durable Global Health Security (GHS) programs to keep Americans safer, stronger, and more prosperous by improving public health globally. It applies lessons learned from recent significant public health events, including outbreaks of viral hemorrhagic fevers (VHF), highly pathogenic strains of influenza, and the COVID-19 pandemic. 

As global leaders in strengthening GHS systems, the U.S. government (USG) will use updated frameworks to advance disease detection, notification, and response strategies. This NOFO’s main outcomes are:

• Use time-bound evidence based frameworks, such as the 7-1-7 framework, to detect and respond to outbreaks more quickly for diseases that threaten global health security and the health of Americans at home and abroad. 
• Support regional and country public health institutions to independently lead preparedness efforts and create resilient, durable, and locally owned health systems. 
• Enhance data systems, lab capacity, and local field epidemiology workforce to effectively combat disease threats of international significance.

No Applicants // Limit: 1 // Tickets Available: 1

Limiting Language
Under this NOFO, you may submit only one application for one program site (Lake County, Indiana; Sandusky and Toledo metro area, Ohio; Brownsville, Texas; Petersburg, Virginia) under your organization’s Unique Entity Identifier (UEI).

Summary
In collaboration with U.S. Department of Health and Human Services (HHS), the Centers for Disease Control and Prevention (CDC), state and federally funded programs, you will implement a project focused on reducing chronic disease rates within a defined geographic area within four communities: Lake County, Indiana; Sandusky and Toledo metro area, Ohio; Brownsville, Texas; Petersburg, Virginia. The goal is to demonstrate how individual and system- level interventions can encourage healthier habits and choices that can reduce the burden of chronic disease in children. When these lifestyle and community changes are maintained over time, reductions in the burden of chronic diseases among adults in the United States may eventually result. Findings from these demonstration programs will inform the potential replication of successful interventions in additional communities. 

Additionally, HHS will use findings from this demonstration project to inform future approaches to funding and measuring effects of novel efforts to improve health for individuals and communities.

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Limiting Language 
Under this NOFO, you may submit only one application under your organization’s Unique Entity Identifier (UEI).

Summary 
The purpose of this Notice of Funding Opportunity (NOFO) is to decrease the impact of specific parasitic infections in the U.S. with public health practices and disease control strategies. The NOFO focuses on three parasitic infection areas: 
• Chagas disease.
• Soil-transmitted helminths. 
• Other parasitic diseases of domestic concern in the U.S. 

This NOFO will continue CDC’s Parasitic Disease Branch work to help healthcare providers (HCPs) better understand, detect, treat, and prevent parasitic infections. Improved understanding and management of parasitic diseases in the U.S. will help make Americans stronger, safer, and more prosperous. There are three components of this NOFO. You may apply for only one: 
• Component A will improve HCPs’ knowledge and practices. Increase testing and management of people with or at risk of Chagas disease. Expand the use of best practices, training tools, and materials. 
• Component B will strengthen public health efforts to monitor and control soil-transmitted helminth infections (like hookworm). It focuses on areas in the Southeastern U.S. (as defined by the U.S. Census Bureau) that are historically affected. 
• Component C will target the prevention, control, health education, and, where applicable, elimination of other parasitic diseases in the U.S. Diseases include cyclosporiasis, cysticercosis, echinococcosis, leishmaniasis, lymphatic filariasis, and toxoplasmosis.

We will not accept proposals focused on malaria, amoebiasis,cryptosporidiosis, giardiasis, or any international activities. Your strategies should aim for significant public health benefits and reach a large portion of at-risk populations.

No Applicants // Limit: 1 // Tickets Available: 1

Limiting Language 
Under this NOFO, you may submit only one application under your organization’s UEI.

Summary
This NOFO focuses on protecting Americans from global health threats across three strategic areas: • Strengthening Early Warning Surveillance. 
• Developing or enhancing electronic tools and interoperable surveillance systems. 
• Improving how surveillance data is used for action. 

This NOFO will support global health security partners to implement surveillance activities that speed up outbreak detection and response, enhance regional and national health system capacities, and strengthen and expand global health partnerships.

Required Delivery Location
 You must conduct the project in these focused regions and countries: 
• Central and South America: Guatemala, Colombia, Ecuador, Peru. 
• East Africa: Ethiopia, Kenya, Tanzania, Uganda. • Eastern Europe/Central Asia: Armenia, Georgia, Kazakhstan, Ukraine. 
• Middle East: Pakistan, Jordan, Egypt. 
• South and Southeast Asia: Bangladesh, India, Cambodia, Indonesia, Thailand, Vietnam. 
• Central and Southern Africa: Cameroon, Dem. Rep. Congo, Mozambique, South Africa, Zambia. 
• West Africa: Burkina Faso, Cote d’Ivoire, Ghana, Guinea, Liberia, Mali, Nigeria, Senegal, Sierra Leone. 
You may propose additional related strategies and activities to achieve the expected outcomes. You may also submit an application supporting activities in any country but are encouraged to submit a proposal that covers at least three of the stated regions and/or countries.

 

No Applicants // Limit: 1 // Tickets Available: 1

Limiting Language 
Under this NOFO, you may submit only one application under your organization’s UEI.

Summary
This notice of funding opportunity (NOFO) strengthens the United States’s capacity to prevent, detect, and respond to infectious disease threats. It improves infrastructure, workforce development, risk and health messaging, and emergency response capabilities. It will help:

• Expand training for infection prevention and control (IPC) and combating antimicrobial resistance (AR). 
• Enhance engagement of frontline healthcare and public health workers. 
• Improve healthcare facility resilience. 
• Improve coordination and surge staffing during public health responses.

No Applicants // Limit: 1 // Tickets Available: 1

Please see the NOFO for required delivery locations where proposed projects must be conducted.

Limiting Language
Under this NOFO, you may submit only one application under your organization’s UEI.

Summary
This NOFO aims to protect Americans from global health threats by focusing on five strategic areas:

• Strengthening public health laboratory systems and services across multiple levels to help create a cohesive network that supports robust public health initiatives.
• Making sure there’s consistent and reliable access to high-quality services around the world by improving essential laboratory quality management systems.
• Building a resilient and well-trained workforce, equipped with the skills to meet evolving health challenges.
• Identifying and managing biological risks to make sure public health laboratory operations are safe and reliable.
•  Reinforcing laboratory preparedness so that Americans can be protected from widespread health threats by making sure that outbreak response is fast and effective.

No Applicants // Limit: 1 // Tickets Available: 1

Limiting Language
You may submit only one application per institution. This is normally identified by having a Unique Entity Identifier (UEI) number.

Summary 
The purpose of this notice of funding opportunity (NOFO) is to expand the network of institutes working with CDC to help eliminate or control non- malaria parasitic threats and neglected tropical diseases (NTDs). This NOFO will focus on threats and diseases that may affect Americans at home or abroad or whose elimination or control would serve other U.S. priorities.

This program will also support research that will provide tools and information to improve NTD and parasitic disease program activities. The program will also integrate evaluation and surveillance activities for multiple NTDs and other parasitic diseases.

No Applicants // Limit: 1 // Tickets Available: 1 

Summary 

This NOFO’s aim is to improve awareness and knowledge of alpha-gal syndrome (AGS) in the United States. AGS is an emerging condition and is not nationally notifiable. This will happen through:

• The creation of a professional network of AGS researchers and public health professionals.
• Improved surveillance.
• Improved communications materials.

This NOFO seeks to improve:

• AGS surveillance.
• Patient care.
• Awareness and understanding.
   

The NOFO’s three main strategies are to:

• Share: Disseminate the latest knowledge about AGS among stakeholders to improve patient care for AGS and the public health response.
  • This includes public health agencies, academic researchers, and
    advocacy groups.
• Track: Conduct active or enhanced surveillance for AGS.
  • This strategy could involve patient populations or geographic locations with limited access to specialized healthcare provider care.
• Educate: Create AGS communications targeted at the general public, AGS patients, and/or people at higher risk for tick encounters (outdoor enthusiasts, dog owners, etc.).
  • Communications targeted at healthcare providers, healthcare provider educational resources, and training would also fall under this strategy.

No Applicants // Limit: 1 // Tickets Available: 1

Limiting Language
Under this NOFO, you may submit only one application under your organization’s Unique Entity Identifier (UEI).

Summary
The purpose of this NOFO is to support community coalitions that work to
prevent and reduce substance use among youth. This NOFO aligns with the
Drug-Free Communities (DFC)’s Support Program’s two goals:
• Establish and strengthen collaboration among community stakeholders
and organizations to address youth substance use.
• Reduce substance use among youth and, over time, reduce substance
use among adults by:
◦ Addressing the factors in a community that increase the risk of
substance use.
◦ Promoting the factors that minimize the risk of substance use.

The DFC program will fund coalitions that haven’t received DFC funding.

Please note: The DFC Program is funded and administered by the White
House Office of National Drug Control Policy (ONDCP). CDC manages the DFC
Program on behalf of ONDCP.