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Optimal Treatment Strategies for use of Anti-Obesity Medications (AOMs) in Children and Adolescents Research Coordinating Center (U24 Clinical Trial Not Allowed)

Apply to Internal Competition // Limit: 1 // Tickets Available: 1

Limiting Language
Only one application per institution (normally identified by having a unique UEI or NIH IPF number) is allowed.

Purpose
This Notice of Funding Opportunity (NOFO) invites applications for a Research Coordinating Center (RCC) to participate in a consortium of clinical centers that will test anti-obesity medication (AOM) treatment strategies for youth with obesity that maximize benefits and minimize risks of AOM use. Such intervention strategies should support the promotion of healthy growth and development; adequate nutritional status/intake, healthy eating and physical activity behaviors; mental health and well-being (e.g., body image, self-esteem, mood, etc.), and quality of life and be feasible to implement in clinical care settings. Priority areas include testing strategies to determine optimal developmental stage for AOM initiation, rate and amount of weight loss, AOM class, dose, frequency, and duration, and content and intensity of adjunct lifestyle therapies that may be imperative to ensure normal psychological and physical development and to potentially avoid lifelong dependence on AOMs. Investigators should also evaluate potential predictors of response/ nonresponse to various treatment strategies under evaluation. The clinical centers may conduct independent or multicenter trials but will collaborate on the development of protocols, use of common measures and data elements, use of a central laboratory and standardized procedures to collect data and biospecimens, and data analyses and manuscripts

The RCC will lead, manage, and harmonize efforts for the Consortium including 1) providing management and administrative support; 2) providing leadership and expertise on statistical design and analysis, 3) providing research coordination with a central laboratory, 4) harmonizing data collection methods and use of common data elements, 5) developing the database; 6) conducting data management and data analyses for Consortium studies; and 7) fostering research collaborations. This NOFO uses a cooperative agreement mechanism (U24) and runs in parallel with a companion NOFO (RFA-DK-27-121).

Full sponsor guidelines are linked here. 
 

Funding Type
External Deadline
10/9/2026
Internal Deadline
Internal Time
5:00PM
Solicitation Type

Optimal Treatment Strategies for use of Anti-Obesity Medications (AOMs) in Children and Adolescents Clinical Centers (U01 Clinical Trial Required)

Apply to Internal Competition // Limit: 1 // Tickets Available: 1

Limiting Language
Only one application per institution (normally identified by having a unique UEI or NIH IPF number) is allowed.


Purpose
This Notice of Funding Opportunity (NOFO) invites applications from clinical centers to participate in a consortium to test anti-obesity medication (AOM) treatment strategies for youth with obesity that maximize benefits and minimize risks of AOM use. Such intervention strategies should support the promotion of healthy growth and development; adequate nutritional status/intake, healthy eating and physical activity behaviors; mental health and well-being (e.g., body image, self-esteem, mood, etc.), and quality of life and be feasible to implement in clinical care settings. Priority areas include testing strategies to determine optimal developmental stage for AOM initiation, rate and amount of weight loss, AOM class, dose, frequency, and duration, and content and intensity of adjunct lifestyle therapies that may be imperative to ensure normal psychological and physical development and to potentially avoid lifelong dependence on AOMs.  Investigators should also evaluate potential predictors of response/ nonresponse to various treatment strategies under evaluation. The clinical centers may conduct independent or multicenter trials but will collaborate on the development of protocols, use of common measures and data elements, use of a central laboratory and standardized procedures to collect data and biospecimens, and data analyses and manuscripts. 

Full sponsor guidelines are linked here. 

Funding Type
External Deadline
10/9/2026
Internal Deadline
Internal Time
5:00PM
Solicitation Type

Rural Cooperative Development Grants

Request Ticket // Limit: 1 // Tickets Available: 1

Limiting Language 
An Applicant may submit only one application in response to a solicitation. All applications submitted, regardless of the Applicant entity name, that include the same Executive Director, employees, Board, advisory boards or committees of an existing Center or a majority thereof will be determined ineligible for funding. NIFA will accept the most recent application if an applicant submits duplicate or multiple submissions.  
Eligibility and Cost Sharing
Applications will only be accepted from nonprofit institutions. A “nonprofit institution” is defined as any organization or institution, including an accredited institution of higher education, no part of the net earnings of which inures, or may lawfully inure, to the benefit of any private shareholder or individual. Applicants must meet the eligibility requirements in 7 CFR 4284.520(a). Applicants are ineligible for assistance through this program if one or more of the items defined in 7 CFR 4284.520(b) occurs. As defined in 7 CFR 4284.522(a), eligible projects must meet all the following requirements.  Failure to meet one or more of these requirements means that the application will not be considered for funding.   

  1. Rurality – All Project activities must serve individuals, Cooperatives and Mutually Owned Businesses, small businesses, or other similar entities in Rural Areas. 
  2. Project Focus – The Project must focus on establishing or operating a Center with the goals of creating jobs in Rural Areas through the development of new Rural Cooperatives, Value-Added processing, and Rural businesses. 
  3. Amount Requested – The amount requested must not exceed the maximum amounts specified in Table 2 of this notice.  
  4. Matching Funds – Matching Funds must be provided as detailed (including example calculations) in Part III, B.   
     

Match Required – Applicants MUST provide a cost-sharing contribution to the Project that is 25 percent (or 5 percent if a 1994 Institution) of the total award cost and follow the requirements in 7 CFR 4284.522(a)(4). Matching Funds may be provided in cash by the Applicant or cash or in-kind by a third party. 

Executive Summary
This notice identifies the objectives for RCDG program projects, deadlines, funding information, eligibility criteria for projects and applicants, and application forms and associated instructions. NIFA requests applications for grants under the RCDG program for FY 2026 to improve the economic condition of rural areas by helping nonprofit organizations who in turn provide technical assistance to start, expand, or improve cooperatives and mutually owned businesses in rural areas. This notice is being issued to allow applicants sufficient time to leverage financing and prepare and submit their applications.  

Estimated funding amounts are not guaranteed and are subject to the availability of appropriated funds.

Research Category
Funding Type
External Deadline
7/24/2026

Public Health Training Centers (PHTC) Program

Limit: 1 // Tickets Available: 0

K. Reynolds (Community, Environment & Policy)

Limiting Language
You may not submit more than one application. If you submit more than one application, we will only accept the last on-time submission.
Summary
The Public Health Training Centers (PHTC) Program aims to increase the knowledge of the public health workforce through traineeships, specialized training and professional development in partnership with state and local health departments, community-based primary care providers, and related organizations (including non-traditional partners) to address public healthcare needs.

Funding Type
External Deadline
7/17/2026

OVC FY 2026 Increasing Services for American Indian and Alaska Native Victims of Human Trafficking in Urban Centers Program

Request Ticket // Limit: 1 (Category 2 only) // Tickets Available: 1

Limiting Language 
You may submit no more than one application in response to this NOFO. You can apply to either Category 1 or Category 2, but not both categories. 

Purpose of the Funding 
The Office of Justice Programs (OJP) is committed to advancing work that furthers the U.S. Department of Justice’s (DOJ) mission to keep our country safe and secure and uphold the rule of law and protect the rights of American citizens. OJP provides federal leadership, funding, and other critical resources to directly support law enforcement, combat violent crime, protect American children, provide services to American crime victims, and address public safety challenges, including human trafficking and the opioid crisis. This is a notice of funding opportunity (NOFO) for the OVC FY2026 Increasing Services for American Indian and Alaska Native Victims of Human Trafficking in Urban Centers Program. This opportunity is intended to increase access to victim services for victims of human trafficking. 

Category 2 Goals and Objectives 
Category 2: Support for Victim Service Providers 

Goal 1: Enhance the capacity of urban Indian-serving organizations to deliver services to AI/AN victims of human trafficking through ongoing guidance and support. 

  • Objective 1: Improve the organizational capacity of funded organizations to provide victim services. 
Research Category
Funding Type
External Deadline
7/23/2026 (Complete and submit SD-424 on Grants.gov), 7/30/2026 (Full Application in JustGrants)

Coccidioidomycosis Collaborative Research Centers (P01 Clinical Trial Not Allowed)

Limit: 1 // Tickets Available: 0

J. Galgiani (Valley Fever Center for Excellence)

Limiting Language
Only one application per institution (normally identified by having a unique entity identifier (UEI) number or NIH IPF number) is allowed.

Funding Opportunity Purpose
The purpose of the notice of funding opportunity (NOFO) is to solicit applications for a Coccidioidomycosis Collaborative Research Centers (CCRC) program. This new initiative will establish highly collaborative, multi-disciplinary, research teams to conduct translational and clinical research to support the development of a Valley fever vaccine as outlined in NIAID’s Strategic Plan for Research to Develop a Valley fever Vaccine.

 


 


 

National Center for Construction Safety and Health Research and Translation (U54)

Limit: 1 // Tickets Available: 0

T. Bheemasetti (Civil and Architectural Engineering and Mechanics) 

Limiting Language
Only one application per institution (normally identified by having a unique UEI number) is allowed. As defined in the HHS Grants Policy Statement, applications received in response to the same NOFO generally are scored individually and then ranked with other applications under peer review in their order of relative programmatic, technical, or scientific merit. CDC/NIOSH will not accept any application in response to this NOFO that is essentially the same as one currently pending initial peer review unless the applicant withdraws the pending application.

Purpose
 
NIOSH is seeking applications from qualified organizations for a National Center for Construction Safety and Health Research and Translation (also known as the NIOSH National Construction Center). Applicants are expected to propose multi-disciplinary approaches for impactful applied and intervention research and hazard identification and controls, to develop partnerships for implementing prevention and intervention activities, and to serve as leaders in research translation and research-to-practice for the protection of construction workers in the United States. The NIOSH National Construction Center will accomplish these goals by 1) integrating and advancing research, 2) translating and disseminating best practices, 3) disseminating information, 4) informing policy, and 5) building capacity. Applicants must describe the occupational health and safety burden(s) addressed in their proposals. In addition, they must link the need for the proposed research and related activities to the planned outputs and outcomes that will help address or alleviate the construction sector burdens described. Applicants should also describe the anticipated impacts and potential outcomes of the proposed research and related activities that will occur during the 5-year project period and beyond.

Funding Type
External Deadline
9/30/2026 (Required LOI); 10/30/2026 (Full Application)

Tuberculosis Research Advancement Centers (TRACs) (P30 Clinical Trial Not Allowed)

No Applicants // Limit: 1 // Tickets Available: 1 

Limiting Language
Only one application per institution (normally identified by having a unique entity identifier (UEI) number or NIH IPF number) is allowed.

No institution may submit, or participate in (as a sub-award), more than one TRAC application.

NOFO Purpose
The purpose of this notice of funding opportunity (NOFO) is to support applications for the Tuberculosis (TB) Research Advancement Centers (TRACs) program. The goal of the TRACs is to develop the next generation of TB researchers and to catalyze multidisciplinary and innovative TB science by providing expertise and resources to facilitate basic and clinical TB research.

Funding Opportunity Goals 
To assist public and private nonprofit institutions and individuals to establish, expand and improve biomedical research and research training in infectious diseases and related areas; to conduct developmental research, to produce and test research materials. To assist public, private and commercial institutions to conduct developmental research, to produce and test research materials, to provide research services as required by the agency for programs in infectious diseases, and controlling disease caused by infectious or parasitic agents, allergic and immunologic diseases and related areas. Projects range from studies of microbial physiology and antigenic structure to collaborative trials of experimental drugs and vaccines, mechanisms of resistance to antibiotics as well as research dealing with epidemiological observations in hospitalized patients or community populations and progress in allergic and immunologic diseases. Because of this dual focus, the program encompasses both basic research and clinical research. 

OJJDP FY25 National Mentoring Resource Center

No Applicants // Limit: 1 // Tickets Available: 1

Limiting Language
An  applicant  may submit  only one  application  in  response  to  this NOFO.  

Applications under  which  two  or  more  entities (project  partners)  would  carry out  the  federal  award  will  be  considered.  However,  only one  entity may be  the  applicant  for  the  NOFO;  any others must  be proposed  as  subrecipients.  See  the  Application  Resource  Guide  for additional  information  on  subawards.  An  entity may be  proposed  as a subrecipient  in  more  than  one  application.  

Executive Summary
This NOFO will  support  OJJDP  mentoring  grantees and  the  mentoring  field  more  broadly  by  maintaining  the  OJJDP  National  Mentoring  Resource  Center  website  and  providing  training  and  technical  assistance  (TTA)  to  OJJDP  grantees.  Please  see  the  Eligible  Applicants  section  for  the  eligibility criteria.   OJP  is committed  to  advancing  work that  furthers DOJ’s mission  to  uphold  the  rule  of  law,  to  keep  our  country safe,  and  to  protect  civil  rights.  OJP  provides federal  leadership,  funding,  and  other  critical  resources to  directly support  law  enforcement,  combat  violent  crime,  protect  American  children,  provide  services to  American  crime  victims,  and  address  public safety challenges,  including  human  trafficking  and  the  opioid  crisis.   

Research Category
Funding Type
External Deadline
5/4/2026

Energy Frontier Research Centers (EFRCs)

Institutionally Coordinated // Limit: 3 // Tickets Available: 0

J. Schaibley (Physics)
D. Soh (Optical Sciences)
S. Ndlovu (Mining Engineering and Mineral Resources)

Limiting Language
Applicant institutions are limited to no more than three pre-applications or applications as the lead institution.

An individual may not be named as the PI (EFRC Director) on more than one pre-application or application. Directors of existing EFRC awards that do not have project end dates in 2026 cannot be named as the EFRC Director on any pre-application or application in response to this NOFO.

There is no limitation to the number of applications on which an institution appears as a subrecipient. 

Should DOE receive submissions in excess of the applicable limits, DOE reserves the right, in its sole discretion, to request additional or clarifying information to ascertain the institution’s intended submissions. Otherwise, DOE will consider the latest received submissions to be the institution’s intended submissions.
• Pre-applications in excess of the limited number of submissions may be discouraged.
• Applications in excess of the limited number of submissions may be declined without review.

Program Description
The DOE SC program in Basic Energy Sciences (BES) announces a re-competition of the Energy Frontier Research Center (EFRC) program. The purpose of this program is to bring together world-class teams of scientists from universities, DOE national laboratories, and other institutions to perform energy-relevant basic research with a scope and complexity beyond what is possible in single-investigator or small-group awards. These multi-investigator, multi-disciplinary centers accelerate transformative scientific advances for the most challenging topics in materials sciences, chemical sciences, geosciences, and biosciences. EFRCs integrate experiments, theory, computation, and AI/ML; develop innovative experimental and theoretical tools that illuminate fundamental processes in unprecedented detail; and create an enthusiastic, interdisciplinary, workforce of energy-focused scientists.

Funding Type
External Deadline
4/1/2026 (Required Pre-Application); 7/1/2026 (Application)