Biomedical, Clinical & Life Sciences

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Limiting Language
An institution may submit only one Center (and related Projects) application in response to this RFP.

Purpose
The intent of this initiative is to support a collaborative network of researchers whose collective efforts will lead to enhanced understanding of the earlier detection and/or delaying progression of valvular heart disease. Therefore, this Request for Proposals seeks applications that can address these critical questions and stimulate significant advances in these areas of valvular heart disease. All proposed projects must address valvular heart disease. Within that context and as presented above, an array of potential areas of investigation exists. Both human studies and appropriately designed animal models that can foster understanding of valvular heart disease may be proposed. 

STUDY POPULATION(S)

• For studies involving human subjects, researchers must ensure that participant populations accurately reflect those affected by the disease under investigation. Efforts should be made to include individuals whose health criteria align with the prevalence and impact of the disease, thereby enhancing the relevance and applicability of the study findings.
  
   
• Important: Applicants should design studies that incorporate both realistic recruitment goals and sufficient statistical power to ensure valid results.

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Limiting Language
Only one application per institution (normally identified by having a unique DUNS number or NIH IPF number) is allowed.

Purpose
This Notice of Funding Opportunity (NOFO) invites applications for the Claude D. Pepper Older Americans Independence Centers (OAICs) award. The goal of the OAIC program is to establish centers of excellence in geriatrics research and research education to increase scientific knowledge leading to better ways to maintain or restore independence in older persons. OAIC awards are designed to develop or strengthen programs that focus on, and sustain progress in, a key area of aging research related to the mission of the OAIC program.

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J. Roveda (Electrical and Computer Engineering)

Limiting Language: 
Only one application per institution (normally identified by having a unique DUNS number or NIH IPF number) is allowed.

Purpose
This Notice of Funding Opportunity (NOFO) invites Center Core (P30) applications for the National Institute on Aging's (NIA) Artificial Intelligence and Technology Collaboratories (AITC) program. The AITC program promotes the development and implementation of artificial intelligence (AI) approaches and technology through research projects for aging and Alzheimer's Disease (AD) and AD-related dementias (ADRD) research. All applications should propose strategies for addressing challenges surrounding AI and technology development and implementation, and to employ, when possible, best practices established in the fields of aging and AD/ADRD.

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K. Lutrick (Family and Community Medicine) 

Limiting Language
Only one person per organization may apply.

Program Description
The Innovation Awards in Community Health supports original and expanded programs that enhance care, improve prevention, expand treatment, and deliver education to underserved populations most vulnerable to infectious diseases. This proposed program will strengthen infectious disease prevention and response through community outreach, patient and staff education, expanded access, and trusted partnerships.

Aligned with the Innovation Awards’ goals, the program will:
• Expand access to vaccine-preventable disease, STI, and outbreak response services through
innovative outreach and delivery models.
• Provide education and awareness campaigns that build trust and improve staff and patient
understanding of prevention and treatment.
• Strengthen the capacity of safety-net providers to deliver high-quality infectious disease services.
• Share outcomes and strategies broadly, helping other clinics and community health organizations
replicate successful approaches.
By combining innovation with trusted, community-based delivery, this program will reduce disparities,
improve resilience, and protect the health of populations most at risk.

Limit: 1 LOI per College

Z. Chen (College of Public Health) - Research Grant
Y. Shirai (COM-T) - Professional Education and Training Grant

Limiting Language
Organizations may submit only one Letter of Inquiry per deadline. Common exceptions include LOIs submitted by separate departments of large universities.

Overview
RRF funds research that seeks to identify interventions, policies and practices to improve the well-being of older adults and/or their caregivers. Preference is given to projects aimed at generating practical knowledge and guidance that can be used by advocates, policy-makers, providers, and the aging network. Of particular interest are:

• Interventional trials; translational studies; and health services and policy research
• Projects that build on the investigator’s past studies
• Proposals that include robust dissemination plans, if appropriate, to assure that findings reach audiences positioned to act on them

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S. Radovick (Clinical and Translational Sciences Institute, COM-T)

Limiting Language
All Clinical and Translational Science Award (UM1 Clinical Trial Optional) (PAR-21-293, PAR-24-272) applicant organizations and active award recipients for are eligible to apply under this NOFO.

Applicant organizations may NOT submit more than one application.

Purpose and Background
The NRSA program has been the primary means of supporting predoctoral and postdoctoral research training programs since enactment of the NRSA legislation in 1974. Research training activities can be in basic biomedical or clinical sciences, in behavioral or social sciences, in health services research, or in any other discipline relevant to the NIH mission.

Institutional NRSA programs allow the Training Program Director/Principal Investigator (Training PD/PI) to select the trainees and develop a program of coursework, research experiences, and technical and/or professional skills development appropriate for the selected trainees. Each program should provide high-quality research training and offer opportunities in addition to conducting mentored research. Trainees should develop the ability to work effectively in teams with colleagues from a variety of backgrounds, and to promote safe and supportive scientific research environments. The grant offsets the cost of stipends, tuition and fees, and training related expenses, including health insurance, for the appointed trainees in accordance with agency-approved support levels

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S. Radovick (Clinical and Translational Sciences Institute, COM-T)

Limiting Language
All Clinical and Translational Science Award (UM1 Clinical Trial Optional) (PAR-21-293, PAR-24-272) applicant organizations and active award recipients for are eligible to apply under this NOFO.

Applicant organizations may NOT submit more than one application.

Purpose
The National Center for Advancing Translational Sciences (NCATS) will award Ruth L. Kirschstein National Research Service Award (NRSA) Predoctoral Institutional Research Training Grants for the Clinical and Translational Science Awards (CTSA) Program (T32) to eligible institutions to create, provide, and disseminate clinical and translational science training and career support programs for individuals seeking a PhD or an equivalent research health professional degree and help ensure a pool of clinical and translational scientist trainees who are equipped with the knowledge, skills and abilities (KSAs) to advance diagnostics, therapeutics, clinical interventions, and behavioral modifications aimed at improving health and support meaningful translational science research projects that address demonstrable needs among stakeholder communities.

NCATS will not accept applications proposing combined predoctoral and postdoctoral training under this Notice of Funding Opportunity (NOFO). Applications proposing postdoctoral research training should apply to the Ruth L. Kirschstein National Research Service Award (NRSA) Postdoctoral Institutional Research Training Grant for the Clinical and Translational Science Awards (CTSA) Program (PAR-25-195).

Applicants interested in providing short-term research experiences should apply to the companion NCATS Clinical and Translational Science Award (CTSA) Program Research Education Grants Programs (R25) (PAR-25-197). A short-term research experience is one where the participant is full-time (40 hours per week) for a period of 10 to 15 weeks, or as specified by the sponsoring institution in accordance with its own policies.

The proposed institutional research training program may complement other ongoing research training and career development programs at the applicant institution, but must be clearly distinct from related programs currently receiving Federal support.

This NOFO does not allow appointed Trainees to lead an independent clinical trial, but does allow them to obtain research experience in a clinical trial on which the PI is a mentor or co-mentor. NIH strongly supports training towards a career in clinically relevant research and so gaining experience in clinical trials under the guidance of a mentor or co-mentor is encouraged.

This limited competition NOFO is part of a required set of companion applications: the Clinical and Translational Science Award (UM1) and companion Institutional Career Development Award (K12). The remaining NOFOs in the suite are optional and include the Ruth L. Kirschstein National Research Service Award (NRSA) institutional training programs (T32 predoctoral and T32 postdoctoral), the Research Education Grant (R25), and the Specialized Innovation Program (RC2). These optional NOFOs are only available to CTSA Program UM1 applicants and award recipients. Applications to the companion NOFOs cannot be awarded until an award has been issued for the UM1. (See Section III. Eligibility Information of this NOFO and the respective NOFOs for more information).

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J. Thanga (Aerospace and Mechanical Engineering) 

Limiting Language 
Only one application per institution (normally identified by having a unique UEI number) is allowed. As defined in the HHS Grants Policy Statement, applications received in response to the same NOFO generally are scored individually and then ranked with other applications under peer review in their order of relative programmatic, technical, or scientific merit. CDC/NIOSH will not accept any application in response to this NOFO that is essentially the same as one currently pending initial peer review unless the applicant withdraws the pending application.

Purpose
NIOSH is seeking applications from qualified organizations for a National Center for Construction Safety and Health Research and Translation (also known as the NIOSH National Construction Center). Applicants are expected to propose multi-disciplinary approaches for impactful applied and intervention research and hazard identification and controls, to develop partnerships for implementing prevention and intervention activities, and to serve as leaders in research translation and research-to-practice for the protection of construction workers in the United States. The NIOSH National Construction Center will accomplish these goals by 1) integrating and advancing research, 2) translating and disseminating best practices, 3) disseminating information, 4) informing policy, and 5) building capacity. Applicants must describe the occupational health and safety burden(s) addressed in their proposals. In addition, they must link the need for the proposed research and related activities to the planned outputs and outcomes that will help address or alleviate the construction sector burdens described. Applicants should also describe the anticipated impacts and potential outcomes of the proposed research and related activities that will occur during the 5-year project period and beyond.

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D. Ferguson (COM-P)

Limiting Language
BRF will only accept one LOI per institution

Overview
Brain Research Foundation’s Annual Seed Grant Program was initiated in 1981. The purpose of our program is to provide start-up monies for new research projects in the field of neuroscience that will likely lead to extramural funding from the National Institutes of Health (NIH) or other outside funding sources. 

The objective of the BRF Seed Grant Program is to support new and innovative projects, especially those of junior faculty, who are working in new research directions. BRF Seed Grant awards are not intended to supplement existing grants

Funding Specifics
1.) Funding is to be directed at pilot research projects that are both innovative and will likely lead to successful grant applications to NIH and other public and private funding entities. 

2.) Assistant Professor – Junior faculty with a new research project that will generate pilot data that will lead to RO1 funding or a comparable outside grant will be first priority. • Must provide abstract and specific aims for current grants and indicate if there is any overlap. 

3.) Associate Professor – Faculty who are pursuing new research directions. • Must explain how the project is a new research direction. • Must provide abstract and specific aims for current grant(s) and indicate if there is any overlap. 

4.) A new technique is not considered a new direction unless it pertains to a different area of study. 

5.) Grants are NOT to be used for bridge funding between grants. 

For full guidelines, please visit https://www.thebrf.org/seed-grants/ 

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Limiting Language
Only one applicant from a university or non-profit research institute will be considered in each application cycle. Institutions should have an internal screening and selection process, as the Foundation will not consider multiple letters of intent received from a single institution. For purposes of this limitation, the Foundation considers the overseeing university to be the institution. Thus, a university with a law school, medical school, several teaching hospitals, and a faculty of arts and sciences may only submit one application in total. If a university system, such as a state-wide university system, comprises several universities, each university within the system may nominate one applicant.

Program Overview
The Greenwall Faculty Scholars Program in Bioethics is a career development award to enable early-career faculty members to carry out innovative bioethics research. It supports research that goes beyond current work in bioethics to help resolve pressing ethical issues in clinical, biomedical, and public health decision-making, policy, and practice, and creates a community that enhances future bioethics research by Scholars and Alums.

Each year, the Foundation selects approximately three Greenwall Faculty Scholars to receive 50 percent salary support for three years to enable them to carry out a specific research proposal and develop their research program.

Scholars and Alums attend twice-yearly meetings, where they present their works in progress, receive feedback and mentoring from the Faculty Scholars Program Committee and other Scholars and Alums, and have the opportunity to develop collaborations with other researchers. Third-year Scholars are expected to help plan these meetings. Ongoing involvement of Alums with the Program provides continued opportunities for professional development and feedback, and engages them in mentoring of early-career Scholars. In addition, all first-year Scholars participate in a philosophical bioethics seminar series; additional professional development opportunities may also be offered.

The Program Committee provides oversight and direction for the Program and is involved not only with selection of the Scholars but also with mentoring and professional development activities.