Upcoming

Apply to Internal Competition // Limit: 1 (Lead Applicant) // Tickets Available: 1

Limiting Language
You can submit only one application for this NOFO. If you submit more than one, we will only review the last timely submission. Any other submissions listing the same entity as the applicant for the same topic area will not be eligible. This limitation does not prohibit you from collaborating on other applications (e.g., as a potential subrecipient or partner) if you are not listed as the applicant on more than one application for each topic area of this NOFO.

Executive Summary
The goal of this award is to develop a potentially revolutionary Light Water Reactor (LWR) Silicon Carbide (SiC) cladding material that can withstand significant accident and transient conditions. This program seeks to support research and development of SiC cladding technology, including mechanical, thermal-hydraulic, high temperature, and corrosion testing for both unirradiated and irradiated SiC cladding samples. This will provide the useful performance data to enable future commercial lead test rods (LTRs) irradiation testing. Irradiation campaigns in research reactors (e.g., INL ATR, ORNL HFIR, MITR) and Post Irradiation Evaluations (PIEs) are expected to provide irradiation performance data for fuel vendor licensing and accident analyses methods needed for NRC licensing review. Improvements in SiC/SiC composite cladding fabrication methods are expected to be made.

Full sponsor guidelines are linked here.

Institutionally Coordinated // Limit: 3* 

For additional information, please contact Marie Teemant. 

Limiting Language
Each institution may submit up to three nominations, one in each disciplinary category of Life Sciences, Physical Sciences & Engineering, and Chemical Sciences.

Program Overview
The Blavatnik National Awards for Young Scientists recognize the United States' most promising faculty-rank researchers in Life Sciences, Physical Sciences & Engineering, and Chemical Sciences. One Blavatnik National Awards Laureate in each disciplinary category will receive $250,000 in unrestricted funds, and additional nominees will be recognized as Finalists, and will receive $15,000 in unrestricted funds.

Eligibility
The nominee must:

• Have been born in or after 1985*.
• Hold a doctorate degree (PhD, DPhil, MD, DDS, DVM, etc.).
• Currently hold a tenured or tenure-track academic faculty position, or equivalent, at an eligible institution in the United States.
• Currently conduct research as a principal investigator in one of the disciplinary categories in Life Sciences, Physical Sciences & Engineering, or Chemical Sciences.

Apply to Internal Competition // Limit: 1 // Tickets Available: 1

Limiting Language
Only one application per institution is allowed, as defined in Section III. 3. Additional Information on Eligibility. 

Please note, under Section III. 3, it states, "Applicant organizations may submit more than one application, provided that each application is scientifically distinct". NIH has clarified the first statement on limiting language, indicating a limit of one, is the correct one.

Purpose of Funding Opportunity
This Notice of Funding Opportunity (NOFO) invites applications for Diabetes Research Centers (DRCs) that are designed to support and enhance the national research effort in diabetes, its complications, and related endocrine and metabolic diseases. The purpose of this Centers program is to bring together basic and clinical investigators to enhance communication, multidisciplinary collaboration, and effectiveness of ongoing research in Diabetes Research Center topic areas. By providing shared access to specialized technical resources (research cores) and supporting a Pilot and Feasibility Program (P&F), DRCs are intended to create an environment that provides the capability for accomplishments greater than those that would be possible by individual research project grant support alone. New Center programs that bring in new approaches, propose unique scientific themes, or provide innovative resources are encouraged. Emphasis will be placed on Center programs that propose enhanced synergies with other NIDDK-funded programs as well as providing a rich mentoring environment for future diabetes researchers. 

Apply to Internal Competition // Limit: 50 (five per topic area) // Tickets Available: 50

Limiting Language 
Please note that we are limiting each university to five total applications per RFI.

Program Description

Full sponsor guidelines are available at this box link (NetID login required). 

The RTX University Research Program provides funding for academic research that aligns with RTX strategic technology priorities and long-term development objectives and its three industry-leading businesses: Collins Aerospace, Pratt & Whitney, and Raytheon. These projects help to strengthen and extend our collaborative research relationships with our select university partners.  Please read all the information below regarding the process and the timeline for awards. 

The ten topics are as follows: 

1. Sensing Systems
2. Advanced Materials and Manufacturing
3. Microelectronics
4. Autonomy
5. Advanced Propulsion
6. Artificial Intelligence
7. Digital Lifecycle
8. Integrated Battlespace
9. Intelligent Aviation
10. Integrated Power and Thermal Systems

Who can apply?

We accept applications from Principal Investigators (PIs) who meet the eligibility criteria:

• PI’s institution: PIs must belong to a university or educational institution.
• PI’s position: PIs must be a full-time professor (adjunct professors and adjunct researchers are not eligible) or researcher and be eligible to supervise Ph.D. students at the PI’s institution.
• Full professors, associate professors, and assistant professors are eligible to apply.

Institutionally Coordinated via Tech Launch Arizona, please contact Doug Hockstad // Limit: 1

Limiting Language
Only one application per institution (normally identified by having a unique NIH IPF number) is allowed.

The primary applicant organization must be a university or other research institution that participates in the NIH STTR program. Participation means that a university or other research institution has been a formal partner to a small business on an STTR award. Many NIH-supported universities or other research institutions will be eligible. Please contact the Scientific/Review staff listed below for clarification.

Purpose
This Notice of Funding Opportunity (NOFO) announces the renewal of the NIH Research Evaluation and Commercialization Hub (REACH) program, established to facilitate and accelerate the translation of academic biomedical discoveries into products that improve patient care and public health. Through this program, NIH will provide the qualifying institutions with the funds to seed the creation of academic entrepreneurship Hubs. Hubs will be responsible for providing innovators with both the initial investment and resources to support the proof-of-concept work and the mentorship in product development and commercialization needed to develop high priority technologies within the NIH's mission. Funded Hubs are intended to work as a consortium to enable: (1) the infrastructure for identifying the most promising technologies, (2) funding for product definition studies (e.g. feasibility studies, prototype development, proof-of-concept studies) provided to individual researchers, (3) access to resources and expertise in areas required for early stage technology development (including scientific, regulatory, reimbursement, business, legal, and project management), and (4) skills development and hands-on experience in entrepreneurship. Establishing public-private partnerships and providing additional non-federal funds will be critical for success. This is a Notice of Funding Opportunity (NOFO) for a Limited Competition that will invite applications from eligible organizations to apply. Please see Section III. Eligibility for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered for funding.
 

Apply to Internal Competition // Limit: 4 (one per program plus one additional possible for select research areas) // Tickets Available: 4
 

Limiting Language

Total submissions allowed per institution:one submission in each program category, plus one additional submission under the funding interest submission, if eligible. 

St. Baldrick’s Foundation has identified the areas below as funding interests and has donors interested in supporting meritorious projects in these areas. To encourage submissions in these priority areas, institutions may submit one additional LOI beyond the standard limited submissions. Only one additional submission is permitted per institution for the entire cycle; this does not allow one additional submission in each program or funding category. 

• Rhabdomyosarcoma 
• Brain tumors –especially atypical teratoid/rhabdoid tumor (AT/RT), diffuse intrinsic pontine glioma (DIPG)/diffuse midline glioma (DMG), and glioblastoma (GBM) 
• Burkitt lymphoma – all types, especially sporadic 
• Rhabdoid tumors - Extrarenal 

Program Descriptions

Full sponsor guidelines are linked here. 

St. Baldrick's Scholars

• The three (3) year Scholar (Career Development) Award, with an option for two (2) additional years based on progress, is meant to help develop the independent research of highly qualified individuals still early in their careers. Recipients are called St. Baldrick's Scholars. Up to $110,000/year, three-year minimum.
• Scholar (Career Development) Award LOI instructions
• Scholar (Career Development) Award Guidelines

St. Baldrick's International Scholars

• This three (3) year award, with an option for two (2) additional years based on progress, is to train researchers from low-and middle-income countries (as classified by the World Bank) to prepare them to fill specific stated needs in an area of childhood cancer research upon returning to their country of origin. Recipients are called St. Baldrick's International Scholars. Up to $110,000/year, three-year minimum.
• International Scholar LOI instructions
• International Scholar Award Guidelines

Survivorship and Supportive Care Research Grant

• These grants are for specific one-year research projects which are hypothesis-driven and focus on areas related to survivorship and supportive care of children and adolescents with cancer. Examples include but are not limited to: studies related to the burden of morbidity, cause-specific mortality, understanding the pathogenesis of treatment-related complications, patient-reported outcomes or quality of life, health communication, health promotion, and psychosocial support across the trajectory from diagnosis to survivorship or end-of-life care.
• Survivorship and Supportive Care Research Grant LOI instructions
• Survivorship and Supportive Care Research Grant Guidelines

Submit Letter of Intent // Limit: 2 (lead organization) // Limit: 2 

Limiting Language
An eligible organization can submit a maximum of two Written Proposals per Topic Announcement for Phase 0 as a lead organization. Senior/Key Personnel may be listed on a maximum of one Written Proposal per Topic Announcement.

Topic Description 
Decades of progress in AI algorithms, robotics, sensing, and embedded computing, combined with accelerating industry investment, have positioned the U.S. to redefine how intelligent systems interact with the physical world. While digital AI has advanced rapidly, the next frontier requires developing intelligent, adaptive, and scalable systems capable of perceiving, acting and learning directly within complex physical environments with adaptive human-robot interaction.

Achieving this vision demands innovations in foundational platform technologies to support situational adaptability, continuous learning, and right-sized simulation-to-reality systems. 

Imagine heterogeneous autonomous swarms in military and disaster triage environments capable of high-stakes collective decision making in collaboration with human counterparts and the situational adaptability to perform complex locomotion, sensing, and targeted delivery tasks. Or bio-inspired robotics that operate with adaptive sensing for reflexive sensor input control, neuromorphic cognitive efficiency, and self-healing materials and behaviors. These advances demand significant, continual, and cross-disciplinary ecosystems to save lives, and catalyze U.S. technological and economic innovation. 

NSF X-Labs teams will target early-stage platform technologies that enable breakthroughs to accelerate entirely new forms of AI integration in physical systems including advanced sensors, robotics, embodied systems, human-robot interfaces, or cyber-physical systems. Examples of relevant Missions include, but are not limited to: technologies to enable new forms of distributed learning and swarming; adaptive behavior in the absence of connectivity; novel algorithms for sensor integration into digital twin or cyber-physical simulations; new capabilities in edge AI for physical systems; new modalities for AI control of emerging robotics such as bio-inspired or biohybrid components; platforms to support the next generation of robotic manufacturing based on mass-customizability and intuitive learning; and breakthroughs in the development of training data that, together with other advances, prepare physical AI systems for real-world variability including interactions with human counterparts. The resultant innovative platform technologies should benefit a broad range of application domains critical to U.S. competitiveness and security, which may include healthcare, national defense, emergency response, advanced manufacturing, and scientific discovery. 

An NSF X-Labs Mission in this Topic must be transformative, accelerating breakthrough R&D in physical AI towards creating or reshaping new lines of research and technologies. Successful teams will develop platform technologies, overcome technical barriers facing AI for physical systems, demonstrate measurable impact on the U.S. science and technology landscape, and position their technologies for widespread use and investment. Teams proposing to this Topic must justify that their proposed Mission will develop a technology not presently supported by existing R&D investments by the U.S. public or private sector. 

Examples of challenges not considered in scope for this Topic include computational or software solutions without practical integration into a physical system, integration of current technologies without significant advancement of the state-of-the-art, development of technologies where the impact is narrow and not widely deployable, fundamental research without potential for application in platform technologies, incremental advancement of the state-of-the-art, or advancement of technologies that are already appropriately developed to the point of full-scale commercialization.

Apply to Internal Competition // Limit: 2 // Tickets Available: 2

Limiting Language 
Submissions will be evaluated to ensure they align with our mission and funding criteria. A limit of two proposals may be submitted from the same institution, researcher, or foundation.

Program Overview
SebastianStrong Foundation is a 501c3 nonprofit organization dedicated to raising awareness of childhood cancer and accelerating the development of more targeted, less toxic treatments by funding bold, early-stage research. Since 2017, we have awarded over $4 million to cutting-edge, peer-reviewed pediatric cancer research. Through strategic partnerships, matched contributions, and follow-on funding secured by investigators, our overall impact now exceeds $6 million.
 

We exist because kids deserve better. Too many promising ideas in pediatric cancer research go unfunded due to limited institutional support, lack of commercial incentive, and minimal government investment, especially for rare and relapsed cancers. At SebastianStrong, we focus exclusively on childhood cancers, where small patient populations often mean traditional funders and pharmaceutical companies overlook research.

ABOUT THE DISCOVERY SCIENCE AWARD

The Discovery Science Award typically provides up to $500,000 in funding for groundbreaking research that aligns with our mission. In select cases, proposals demonstrating exceptional potential for impact and scalability may be considered for higher levels of support.

Our Scientific Advisory Board, composed of leading pediatric oncologists and researchers, conducts a two-stage review process. First, Letters of Intent (LOIs) are evaluated to identify projects that best align with our mission and funding priorities. Selected applicants are then invited to submit a full proposal, which is reviewed in detail to determine final award decisions. Funding recommendations are made by the Scientific Advisory Board and approved by the Foundation’s Board of Directors.

To be considered for funding, proposals must meet the following criteria:

1. Are focused on pediatric cancer
2. Will lead to less toxic, more targeted treatments
3. Are clearly communicated in lay terms (accessible to our Board and donor community)
4. Demonstrate strong potential to progress toward a clinical trial in 1-3 years

We welcome new, ongoing, and updated peer-reviewed research. However, we do not accept in-progress or ongoing clinical trials. Any author or researcher conflict of interest must be disclosed at the time of submission. All submissions are treated as CONFIDENTIAL and are accessible only to members of SebastianStrong’s Board of Directors and Scientific Advisory Board until the time of award. We are happy to execute NDAs upon request.

WHAT WE’RE LOOKING FOR

SebastianStrong funds one or more proposals each year that advance meaningful change in pediatric cancer treatment. We are especially interested in research that:

• Focuses on pediatric cancers with low survival rates or high relapse rates
• Has transitional potential within 36 months
• Pursues underfunded or unconventional approaches that could change the status quo

Apply to Internal Competition // Limit: 5 (Standard, Collaboration, and Bridge grant types) // Tickets Available: 4

S. Grutzmacher (Competitive Renewal, Cooperative Extension)

Limiting Language 
For FY 2026, there is a five application limit on the number of Regular/Standard or Collaboration applications that can be submitted by an institution. Per clarification from NIFA, the bridge grant is a subset of the standard/regular grant and thus are also part of the 5 application limit.

Executive Summary
The HSI Education Grants Program, under assistance listing number 10.223, will promote and strengthen the ability HSIs to carry out education, applied research, and related community development programs. This program encourages innovative teaching, education, or related community development proposals with the potential to impact and become models for other institutions at the regional or national level. Applications may propose, as part of a formal education and teaching program, that students gain experience with an applied research and community outreach activity. While HSIs are the only eligible entities to apply for this NOFO, funded projects should benefit the entire population at the institution, not solely the Hispanic population.

The program page is linked here.

Internal Competition Under Peer Review // Limit: 2 // Tickets Available: 1* 

H. Haeger (Education, Competitive Resubmission)

* Please note the number of limited submissions tickets available in this internal competition is subject to change based on the review scores of proposals submitted to the March 2026 deadline. One or both prior applicants may qualify for a competitive resubmission under our limited submissions policies. As of 10/2, we are still awaiting NSF's feedback on one March 2026 proposal. 

Limiting Language
Limit on Number of Proposals per Organization: 2

For a given S-STEM deadline, an institution may submit up to two proposals in which it will be directly involved in providing scholarships. Multiple proposals from an institution must not overlap with regard to S-STEM eligible disciplines. See Additional Eligibility Information below for more details (see IV. Eligibility Information).

Institutions with a current S-STEM award should wait at least until the end of the third year of execution of their current award before submitting a new Track 2 or Track 3 S-STEM proposal focused on students pursuing degrees in the same discipline(s).

Please see the table below for current and pending institutional S-STEM awards and proposals, March 2027 proposals should not overlap with diciplines listed below:

Program Overview 
The main goal of the S-STEM program is to enable academically talented, low-income students to pursue successful careers in promising STEM fields. Ultimately, the S-STEM program seeks to increase the number of academically promising low-income students who graduate with an S-STEM eligible degree and contribute to the American innovation economy with their STEM knowledge. Recognizing that financial aid alone cannot increase retention and graduation in STEM, the program provides awards to institutions of higher education (IHEs) not only to fund scholarships, but also to adapt, implement, and study evidence-based curricular and co-curricular[a] activities that have been shown to be effective in supporting recruitment, retention, transfer (if appropriate), student success, academic/career pathways, and graduation in STEM.

To be eligible, scholars must be domestic low-income students with academic ability, talent, or potential and demonstrated unmet financial need who are enrolled in an associate, baccalaureate, or graduate degree program in an S-STEM eligible discipline. Proposers must provide an analysis that articulates the characteristics and academic needs of the population of students they are trying to serve. NSF is particularly interested in supporting the attainment of degrees in fields identified as critical needs for the Nation. It is up to the proposer to make a compelling case that such a field serves a critical need in the United States.

[a] an activity at a school or college pursued in addition to the normal course of study.

S-STEM Eligible Degree Programs

• Associate of Arts, Associate of Science, Associate of Engineering, and Associate of Applied Science
• Bachelor of Arts, Bachelor of Science, Bachelor of Engineering and Bachelor of Applied Science
• Master of Arts, Master of Science, and Master of Engineering
• Doctoral (Ph.D. or other comparable doctoral degree)

S-STEM Eligible Disciplines

Disciplinary fields in which research is funded by NSF, including technology fields associated with the S-STEM-eligible disciplines (e.g., biotechnology, chemical technology, engineering technology, information technology, etc.).

The following degrees and disciplines are excluded:

• Clinical degree programs, including medical degrees, nursing, veterinary medicine, pharmacy, physical therapy, and others not funded by NSF, are ineligible degrees.
• Programs for STEM teacher certification or licensure currently covered by the Robert Noyce Teacher Scholarship program (NOYCE) are ineligible for S-STEM funding.
• Business school programs that lead to Bachelor of Arts or Science in Business Administration degrees (BABA/BSBA/BBA) are not eligible for S-STEM funding.
• Masters and Doctoral degrees in Business Administration are also excluded.

Proposers are strongly encouraged to contact Program Officers before submitting a proposal if they have questions concerning degree or disciplinary eligibility.

The S-STEM program particularly encourages proposals from 2-year institutions, predominately undergraduate institutions, and urban, suburban, and rural public institutions.

Full sponsor guidelines are linked here.