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2027-28 ASCENDR Research Program

Apply to Internal Competition // Limit: 2 // Tickets Available: 2

Limiting Language
Each eligible institution may submit a maximum of two proposals for the 2027–2028 funding cycle.
 

Overview
The ASCENDR Research Program is a competitive, faculty-led program designed to advance research aligned with the U.S. Department of War’s (DoW) science and technology priorities. Through targeted research funding, faculty across HSRU Alliance institutions will lead projects that address real-world defense challenges while engaging graduate students in meaningful research experiences. The program supports the development of innovative solutions in key technical areas and fosters deeper collaboration between academic researchers and the defense enterprise.

Critical Technology Areas
For the 2027–2028 funding cycle, proposed research must contribute to one or more of the six DoW Critical Technology Areas identified for this competition. Proposals may address a Critical Technology Area directly or advance foundational, enabling, or cross-cutting research with a clearly articulated connection to one or more of the areas

  1. Applied Artificial Intelligence (AAI)
    Research that advances the effective application of artificial intelligence, machine learning, data analytics, and related computational methods to improve decision-making and operational efficiency. Relevant research may include algorithms, data methods, autonomy, human-machine teaming, modeling and simulation, trustworthy and assured AI, and approaches that enable reliable AI adoption across defense domains.
  2. Biomanufacturing (BIO)
    Research that harnesses living systems, biological processes, and bioengineering to produce critical materials, substances, or capabilities at scale. Relevant research may include bioprocess development, synthetic biology, biofabrication, scale-up, quality and reproducibility, and approaches that reduce supply-chain vulnerabilities and strengthen resilience.
  3. Contested Logistics Technologies (LOG)
    Research that enables forces to operate and sustain missions when transportation, supply networks, communications, or infrastructure are disrupted, degraded, or denied. Relevant research may include energy storage and power systems, resilient supply networks, predictive logistics, autonomous or distributed resupply, maintenance and sustainment, and production at the point of need.
  4. Quantum and Battlefield Information Dominance (Q-BID)
    Research that advances technologies needed to maintain information advantage in degraded or denied environments, including resilient communications, precision navigation and timing, sensing, and electromagnetic-spectrum maneuverability. Relevant research may draw on quantum science and engineering, radio-frequency technologies, photonics, radar and electronic warfare, secure networks, signal processing, and other approaches that improve the availability, accuracy, and survivability of battlefield information.
  5. Scaled Directed Energy (SCADE)
    Research that advances scalable and affordable high-energy laser and high-power microwave capabilities for the precise neutralization of threats. Relevant research may include energy sources, materials and components, power and thermal management, beam generation and control, modeling and testing, manufacturability, and approaches that overcome cost and production barriers.
  6. Scaled Hypersonics (SHY)
    Research that enables the affordable and scalable development of systems operating at Mach 5 or greater. Relevant research may include propulsion, aerothermodynamics, high-temperature materials and structures, thermal protection, guidance, navigation and control, sensing, modeling and simulation, testing, and manufacturing approaches that improve speed, precision, survivability, and production at scale

Eligibility

The proposal must originate from an HSRU member institution in good standing.

  • Principal Investigator and Co-Principal Investigator(s) must be a Research Faculty member or Tenure/Tenure Track Faculty member that is early to mid-career, defined as within the first 8 years of their professional research career.     
  • The Principal Investigator must hire and integrate at least one Graduate Research Assistant for this project. The graduate assistant must be enrolled at the start of the project and maintain enrollment eligibility throughout the proposed project.  
  • All PIs, Co-PIs, and the graduate assistant working on this project must be U.S. Persons, defined as U.S. born or U.S. Naturalized Citizens.
  • The Principal Investigator and Co-PIs must agree to jointly participate in the ASCENDR Leadership Program.

Full sponsor guidelines are linked here.

Research Category
Funding Type
External Deadline
2/1/2027
Internal Deadline
Internal Time
5:00PM

2027 National Digital Newspaper Program

Apply to Internal Competition // Limit: 1 // Tickets Available: 1

Limiting Language
An organization may submit only one application under this notice.

If you submit multiple applications, NEH will accept only your last validated submission prior to the deadline under the applicable Grants.gov funding opportunity.

Purpose
NDNP is a partnership between NEH and the Library of Congress (LOC) to create a national digital resource of historically significant newspapers published between 1690 and 1963, from all 56 states and U.S. jurisdictions. LOC will permanently maintain this freely accessible, searchable online database (Chronicling America: Historic American Newspapers). An accompanying national newspaper directory of bibliographic and holdings information directs users to newspaper titles available in all formats. LOC also will digitize newspaper pages drawn from its own collections and contribute them to Chronicling America.

If your application is successful, you will select newspapers published in states or jurisdictions between 1690 and 1963 and, over a period of two years, convert approximately 100,000 pages into digital files (preferably from microfilm), according to the technical guidelines outlined by LOC. 

NEH welcomes applications that involve collaboration between state and jurisdictional partners, which might involve arrangements to manage the creation and delivery of digital files; regular and ongoing consultation about project management; or formal training for project staff. States and jurisdictions are encouraged to digitize titles published within their current geographic boundaries, including those from Native American Tribal nations, but cases for digitization beyond such boundaries can be made. For example, a state may digitize Native American newspapers that were published in another state, or a state may partner with a jurisdiction to digitize the newspapers from there. If you propose to digitize titles published outside of what is now your state or jurisdiction, you must provide the rationale for doing so. 

NDNP supports dissemination activities that engage the wider public in exploring the digitized content, within limits. Your budget may include staff time, consultation with outside experts, and other eligible expenses related to disseminating NEH-funded products, but the primary purpose of this program is to create a national digital resource of historically significant newspapers. 

Your proposed project must include an advisory board. The advisory board could include scholars, teachers, traditional knowledge keepers, librarians, and archivists at a variety of institutions, and the board should be involved in selecting the newspapers to be digitized. The advisory board should also help disseminate information about the project’s progress and Chronicling America more generally. NEH has programmatic expectations depending on how many NDNP awards your state or jurisdiction has previously received and will consider the number of previous NDNP awards when making funding decisions.

Full sponsor guidelines are linked here. 

Research Category
Funding Type
External Deadline
1/13/2027
Internal Deadline
Internal Time
5:00PM

Susan G. Komen Inflammatory Breast Cancer (IBC) Research Grant: Biological Underpinnings of IBC

Apply to Internal Competition // Limit: 1 // Tickets Available: 1

Limited Language
This is a limited submission opportunity: each institution may nominate ONE applicant for this funding opportunity 

Program Overview
At Susan G. Komen®, we are committed to saving lives by meeting the most critical needs in our communities and investing in breakthrough research to conquer deadly and aggressive breast cancers. We are determined to change the unacceptable reality that each year about 43,000 people in the U.S. will die from breast cancer. As part of this goal, we are focused on improving the care and outcomes for people with inflammatory breast cancer (IBC), a rare and highly aggressive form of breast cancer.  

IBC is characterized by tumor cell emboli blocking the breast lymph vessels. This blockage causes inflammatory-like changes in the breast, including swelling and skin reddening. The American Joint Committee on Cancer (AJCC) guidelines define IBC by the rapid onset (less than 6 months) of erythema occupying at least 1/3 of the breast, edema, peau d’ orange (orange peel-like appearance) and/or warmth (with or without an underlying mass), and pathologic confirmation of invasive carcinoma. Although IBC has been recognized as a distinct form of breast cancer for over a century, its etiology and underlying biological mechanisms remain poorly understood. Consequently, no validated, widely adopted IBC-specific biomarkers or targeted therapies exist, and current management is largely informed by evidence from non-IBC breast cancer. This limited understanding of IBC biology remains a significant barrier to the development of more precise diagnostic and therapeutic approaches, highlighting the need for research focused on the unique mechanisms driving the disease. Therefore, the goal of the Inflammatory Breast Cancer (IBC) Research Grant is to support innovative, hypothesis-driven research that advances our understanding of the biological underpinnings of IBC and opens new avenues of investigation into the disease.  

To identify areas where investment could have the greatest impact, the Susan G. Komen-IBCRF IBC Collaborative, in partnership with the Milburn Foundation, convened the Biology of IBC Task Force, a group of IBC researchers and patient advocates. The Task Force identified three broad areas of scientific opportunity that require significant investigation to advance the field: 

  • 1. IBC onset and development, including studies focused on the tumor and host microenvironment, epigenetic and proteomic drivers of disease, host genetic factors and biological contributors to health disparities. 

    2. IBC metastatic dissemination, including mechanisms of cell migration and mobility, biological characteristics associated with therapeutic response and the role of tumor and host, epigenetic and proteomic factors in IBC disease progression. 

    3. IBC monitoring and detection, including approaches to detect minimal residual disease (MRD), improve prognostication, assess therapeutic response and advance theragnostic strategies. 

Eligibility 
Applicant/PIs and Institutions must conform to the following eligibility criteria to apply for an Inflammatory Breast Cancer Research Grant. Grants will be awarded to a single Principal Investigator (PI). Co-Principal Investigators (Co-PIs) are not allowed. CoInvestigators are permitted. 
Applicant/PI 

  • Must be nominated as the sole Applicant/PI from their institution by the Institution’s Office of Sponsored Programs, Grants Office, or equivalent. This is a limited submission opportunity, and the Applicant/PI cannot self-nominate.  
  • Must have a doctoral degree, such as M.D., Ph.D., D.Ph., D.O. or equivalent. 
  • Must hold a full-time faculty appointment or have a formal offer letter from the Institution that confirms position and start date by the Full Application due date (January 18, 2027), documented by the Applicant/PI Biosketch.  
  • May NOT be the PI of an active Komen Grant that includes specific aims or objectives focused on IBC at the Full Application due date (January 18, 2027).  
  • May NOT be the PI of two or more active Komen Grants at the Full Application due date (January 18, 2027) 
  • Must ensure that all past Komen-funded Grants are up to date and in compliance with all Komen requirements, e.g., progress and financial report submissions, IRB approvals, etc. by the Full Application due date (January 18, 2027), if applicable. 
  • Is not required to be a U.S. citizen or permanent resident. 
  • The institution-nominated Applicant/PI may submit only one Letter of Intent in response to this funding announcement.  
Funding Type
External Deadline
11/30/2026 (Required LOI); 1/18/2026 (Invited Full Application)
Internal Deadline
Internal Time
5:00PM
Solicitation Type

DOE Silicon Carbide Cladding Lead Test Rod Development - Phase 1

Apply to Internal Competition // Limit: 1 (Lead Applicant) // Tickets Available: 1

Limiting Language
You can submit only one application for this NOFO. If you submit more than one, we will only review the last timely submission. Any other submissions listing the same entity as the applicant for the same topic area will not be eligible. This limitation does not prohibit you from collaborating on other applications (e.g., as a potential subrecipient or partner) if you are not listed as the applicant on more than one application for each topic area of this NOFO.

Executive Summary
The goal of this award is to develop a potentially revolutionary Light Water Reactor (LWR) Silicon Carbide (SiC) cladding material that can withstand significant accident and transient conditions. This program seeks to support research and development of SiC cladding technology, including mechanical, thermal-hydraulic, high temperature, and corrosion testing for both unirradiated and irradiated SiC cladding samples. This will provide the useful performance data to enable future commercial lead test rods (LTRs) irradiation testing. Irradiation campaigns in research reactors (e.g., INL ATR, ORNL HFIR, MITR) and Post Irradiation Evaluations (PIEs) are expected to provide irradiation performance data for fuel vendor licensing and accident analyses methods needed for NRC licensing review. Improvements in SiC/SiC composite cladding fabrication methods are expected to be made.

Full sponsor guidelines are linked here.

Funding Type
External Deadline
12/7/2026
Internal Deadline
Internal Time
5:00PM

2027 Blavatnik National Awards for Young Scientists

Institutionally Coordinated // Limit: 3* 

For additional information, please contact Marie Teemant. 

Limiting Language
Each institution may submit up to three nominations, one in each disciplinary category of Life Sciences, Physical Sciences & Engineering, and Chemical Sciences.


Program Overview
The Blavatnik National Awards for Young Scientists recognize the United States' most promising faculty-rank researchers in Life Sciences, Physical Sciences & Engineering, and Chemical Sciences. One Blavatnik National Awards Laureate in each disciplinary category will receive $250,000 in unrestricted funds, and additional nominees will be recognized as Finalists, and will receive $15,000 in unrestricted funds.

Eligibility
The nominee must:

  • Have been born in or after 1985*.
  • Hold a doctorate degree (PhD, DPhil, MD, DDS, DVM, etc.).
  • Currently hold a tenured or tenure-track academic faculty position, or equivalent, at an eligible institution in the United States.
  • Currently conduct research as a principal investigator in one of the disciplinary categories in Life Sciences, Physical Sciences & Engineering, or Chemical Sciences.
Funding Type
External Deadline
12/2/2026 (Nominations); 12/16/2026 (Letters of Support)
Solicitation Type

Diabetes Research Centers (P30 Clinical Trial Optional)

Apply to Internal Competition // Limit: 1 // Tickets Available: 1

Limiting Language
Only one application per institution is allowed, as defined in Section III. 3. Additional Information on Eligibility. 

Please note, under Section III. 3, it states, "Applicant organizations may submit more than one application, provided that each application is scientifically distinct". NIH has clarified the first statement on limiting language, indicating a limit of one, is the correct one.

Purpose of Funding Opportunity
This Notice of Funding Opportunity (NOFO) invites applications for Diabetes Research Centers (DRCs) that are designed to support and enhance the national research effort in diabetes, its complications, and related endocrine and metabolic diseases. The purpose of this Centers program is to bring together basic and clinical investigators to enhance communication, multidisciplinary collaboration, and effectiveness of ongoing research in Diabetes Research Center topic areas. By providing shared access to specialized technical resources (research cores) and supporting a Pilot and Feasibility Program (P&F), DRCs are intended to create an environment that provides the capability for accomplishments greater than those that would be possible by individual research project grant support alone. New Center programs that bring in new approaches, propose unique scientific themes, or provide innovative resources are encouraged. Emphasis will be placed on Center programs that propose enhanced synergies with other NIDDK-funded programs as well as providing a rich mentoring environment for future diabetes researchers. 

Funding Type
External Deadline
1/27/2027
Internal Deadline
Internal Time
5:00PM
Solicitation Type

2027 RTX University Research Program - Ten Topic Areas

Apply to Internal Competition // Limit: 50 (five per topic area) // Tickets Available: 50

Limiting Language 
Please note that we are limiting each university to five total applications per RFI.

Program Description

Full sponsor guidelines are available at this box link (NetID login required). 

The RTX University Research Program provides funding for academic research that aligns with RTX strategic technology priorities and long-term development objectives and its three industry-leading businesses: Collins Aerospace, Pratt & Whitney, and Raytheon. These projects help to strengthen and extend our collaborative research relationships with our select university partners.  Please read all the information below regarding the process and the timeline for awards. 

The ten topics are as follows: 

  1. Sensing Systems
  2. Advanced Materials and Manufacturing
  3. Microelectronics
  4. Autonomy
  5. Advanced Propulsion
  6. Artificial Intelligence
  7. Digital Lifecycle
  8. Integrated Battlespace
  9. Intelligent Aviation
  10. Integrated Power and Thermal Systems

Who can apply?

We accept applications from Principal Investigators (PIs) who meet the eligibility criteria:

  • PI’s institution: PIs must belong to a university or educational institution.
  • PI’s position: PIs must be a full-time professor (adjunct professors and adjunct researchers are not eligible) or researcher and be eligible to supervise Ph.D. students at the PI’s institution.
  • Full professors, associate professors, and assistant professors are eligible to apply.
Funding Type
External Deadline
11/19/2026 (RFI); 2/4/2027 (RFP)
Internal Deadline
Internal Time
5:00PM
Sponsor
Solicitation Type

Limited Competition: NIH Research Evaluation and Commercialization Hubs (REACH) (SB0 Clinical Trial Optional)

Institutionally Coordinated via Tech Launch Arizona, please contact Doug Hockstad // Limit: 1

 

Limiting Language
Only one application per institution (normally identified by having a unique NIH IPF number) is allowed.

The primary applicant organization must be a university or other research institution that participates in the NIH STTR program. Participation means that a university or other research institution has been a formal partner to a small business on an STTR award. Many NIH-supported universities or other research institutions will be eligible. Please contact the Scientific/Review staff listed below for clarification.

Purpose
This Notice of Funding Opportunity (NOFO) announces the renewal of the NIH Research Evaluation and Commercialization Hub (REACH) program, established to facilitate and accelerate the translation of academic biomedical discoveries into products that improve patient care and public health. Through this program, NIH will provide the qualifying institutions with the funds to seed the creation of academic entrepreneurship Hubs. Hubs will be responsible for providing innovators with both the initial investment and resources to support the proof-of-concept work and the mentorship in product development and commercialization needed to develop high priority technologies within the NIH's mission. Funded Hubs are intended to work as a consortium to enable: (1) the infrastructure for identifying the most promising technologies, (2) funding for product definition studies (e.g. feasibility studies, prototype development, proof-of-concept studies) provided to individual researchers, (3) access to resources and expertise in areas required for early stage technology development (including scientific, regulatory, reimbursement, business, legal, and project management), and (4) skills development and hands-on experience in entrepreneurship. Establishing public-private partnerships and providing additional non-federal funds will be critical for success. This is a Notice of Funding Opportunity (NOFO) for a Limited Competition that will invite applications from eligible organizations to apply. Please see Section III. Eligibility for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered for funding.
 

Research Category
Funding Type
External Deadline
11/10/2026
Solicitation Type

St. Baldrick’s Childhood Cancer Research Foundation: Spring 2027 Grant Cycle (Scholars, International Scholars, Survivorship and Supportive Care Research Grant Types)

Apply to Internal Competition // Limit: 4 (one per program plus one additional possible for select research areas) // Tickets Available: 4
 

Limiting Language

Total submissions allowed per institution:one submission in each program category, plus one additional submission under the funding interest submission, if eligible. 

St. Baldrick’s Foundation has identified the areas below as funding interests and has donors interested in supporting meritorious projects in these areas. To encourage submissions in these priority areas, institutions may submit one additional LOI beyond the standard limited submissions. Only one additional submission is permitted per institution for the entire cycle; this does not allow one additional submission in each program or funding category. 

  • Rhabdomyosarcoma 
  • Brain tumors –especially atypical teratoid/rhabdoid tumor (AT/RT), diffuse intrinsic pontine glioma (DIPG)/diffuse midline glioma (DMG), and glioblastoma (GBM) 
  • Burkitt lymphoma – all types, especially sporadic 
  • Rhabdoid tumors - Extrarenal 

Program Descriptions

Full sponsor guidelines are linked here. 

St. Baldrick's Scholars

St. Baldrick's International Scholars

  • This three (3) year award, with an option for two (2) additional years based on progress, is to train researchers from low-and middle-income countries (as classified by the World Bank) to prepare them to fill specific stated needs in an area of childhood cancer research upon returning to their country of origin. Recipients are called St. Baldrick's International Scholars. Up to $110,000/year, three-year minimum.
  • International Scholar LOI instructions
  • International Scholar Award Guidelines

Survivorship and Supportive Care Research Grant

  • These grants are for specific one-year research projects which are hypothesis-driven and focus on areas related to survivorship and supportive care of children and adolescents with cancer. Examples include but are not limited to: studies related to the burden of morbidity, cause-specific mortality, understanding the pathogenesis of treatment-related complications, patient-reported outcomes or quality of life, health communication, health promotion, and psychosocial support across the trajectory from diagnosis to survivorship or end-of-life care.
  • Survivorship and Supportive Care Research Grant LOI instructions
  • Survivorship and Supportive Care Research Grant Guidelines
Funding Type
External Deadline
12/8/2026 (Required LOI); 3/5/2027 (Invited Full Proposals)
Internal Deadline
Internal Time
5:00PM
Solicitation Type

NSF X-Labs Initiative – AI for Physical Systems

Submit Letter of Intent // Limit: 2 (lead organization) // Limit: 2 

Limiting Language
An eligible organization can submit a maximum of two Written Proposals per Topic Announcement for Phase 0 as a lead organization. Senior/Key Personnel may be listed on a maximum of one Written Proposal per Topic Announcement.

Topic Description 
Decades of progress in AI algorithms, robotics, sensing, and embedded computing, combined with accelerating industry investment, have positioned the U.S. to redefine how intelligent systems interact with the physical world. While digital AI has advanced rapidly, the next frontier requires developing intelligent, adaptive, and scalable systems capable of perceiving, acting and learning directly within complex physical environments with adaptive human-robot interaction.

Achieving this vision demands innovations in foundational platform technologies to support situational adaptability, continuous learning, and right-sized simulation-to-reality systems. 

Imagine heterogeneous autonomous swarms in military and disaster triage environments capable of high-stakes collective decision making in collaboration with human counterparts and the situational adaptability to perform complex locomotion, sensing, and targeted delivery tasks. Or bio-inspired robotics that operate with adaptive sensing for reflexive sensor input control, neuromorphic cognitive efficiency, and self-healing materials and behaviors. These advances demand significant, continual, and cross-disciplinary ecosystems to save lives, and catalyze U.S. technological and economic innovation. 

NSF X-Labs teams will target early-stage platform technologies that enable breakthroughs to accelerate entirely new forms of AI integration in physical systems including advanced sensors, robotics, embodied systems, human-robot interfaces, or cyber-physical systems. Examples of relevant Missions include, but are not limited to: technologies to enable new forms of distributed learning and swarming; adaptive behavior in the absence of connectivity; novel algorithms for sensor integration into digital twin or cyber-physical simulations; new capabilities in edge AI for physical systems; new modalities for AI control of emerging robotics such as bio-inspired or biohybrid components; platforms to support the next generation of robotic manufacturing based on mass-customizability and intuitive learning; and breakthroughs in the development of training data that, together with other advances, prepare physical AI systems for real-world variability including interactions with human counterparts. The resultant innovative platform technologies should benefit a broad range of application domains critical to U.S. competitiveness and security, which may include healthcare, national defense, emergency response, advanced manufacturing, and scientific discovery. 

An NSF X-Labs Mission in this Topic must be transformative, accelerating breakthrough R&D in physical AI towards creating or reshaping new lines of research and technologies. Successful teams will develop platform technologies, overcome technical barriers facing AI for physical systems, demonstrate measurable impact on the U.S. science and technology landscape, and position their technologies for widespread use and investment. Teams proposing to this Topic must justify that their proposed Mission will develop a technology not presently supported by existing R&D investments by the U.S. public or private sector. 

Examples of challenges not considered in scope for this Topic include computational or software solutions without practical integration into a physical system, integration of current technologies without significant advancement of the state-of-the-art, development of technologies where the impact is narrow and not widely deployable, fundamental research without potential for application in platform technologies, incremental advancement of the state-of-the-art, or advancement of technologies that are already appropriately developed to the point of full-scale commercialization.

Funding Type
External Deadline
1/7/2027
Internal Deadline
Internal Time
5:00PM
Solicitation Type