early career

Institutionally coordinated // S. Song (Biomedical Engineering)
For information, please contact: Marie Teemant, Associate for Research Development

The CCR Grants have fostered promising breast cancer researchers who are in the early stages of their faculty careers by providing support for up to three years of “protected time” for research career development under the guidance of a Mentor Committee. The Foundation is especially interested in hypothesis-driven studies that target breast cancer, in the development of strategies for earlier diagnosis, reduce risk of breast cancer, or increase the effectiveness of current therapies to lead to longer and better-quality outcomes for patients.  They may be considered basic, translational, clinical and/or population science. 

Award: Up to $150,000 per year (combined direct and indirect costs) for up to three years ($450,000).

Eligibility:

• Must have a doctoral degree, such as M.D., Ph.D., Dr.P.H., D.O., or equivalent.
• Must currently hold a full-time faculty appointment or have a formal offer letter from the Institution that confirms position and start date by the Application due date (October 9, 2024).
• Must not have held any faculty appointment, including non-tenure and tenure track appointments combined, for more than a total of 6 years by the Application due date.
• Must not simultaneously hold any other Grant awarded by Susan G. Komen.
• Must not currently be or have been a Principal Investigator on an existing NIH R01 grant or their equivalent as of the date of Award Notification (on or around April 15, 2025).
• Must conduct the proposed research and training at the Lead Mentor’s U.S. based institution.
• Must have adequate space and facilities to conduct the proposed research and must be able to devote at least 75% of full-time effort to breast cancer research and activities.

*The University of Arizona Cancer Center (UACC) can nominate up to two applicants but only if at least one of the two nominees identifies as as someone from groups shown to be historically minoritized and marginalized in biomedical research from National Science Foundation data (details outlined in RFA).

For more information please contact UACC-preaward@arizona.edu

Apply to Internal Competition // Limit: 2 // Tickets Available: 2*

This grant mechanism aims to help outstanding senior postdoctoral fellows and clinical fellows, working under the guidance of a mentor, launch their competitive, independent breast cancer research careers. Career Transition Awards provide up to five years of funding in two phases: Phase 1 supports the final years of mentored, postdoctoral training; and Phase 2 supports the independent research of the early career, tenure-track investigators. 

Research projects must be hypothesis-driven, breast cancer-focused studies. They may be considered basic, translational, clinical and/or population science. 

Komen’s research priorities are conquering metastatic and aggressive breast cancers, advancing personalized breast cancer care throughout the continuum of care and eliminating breast cancer disparities and inequities. 

Eligibility:

• Individuals pursuing independent breast cancer research careers who are in the final years of mentored postdoctoral research training positions with no more than five years of total postdoctoral research experience at the time of Letter of Intent submission (August 7, 2024). For this application clinical fellows are considered eligible and equal to the postdoctoral rank.
• Must have a doctoral degree, including M.D., Ph.D., Dr.P.H., D.O., or equivalent.
• May not hold any appointment designated as faculty (e.g., assistant professor, clinical assistant professor, faculty-level instructor, or equivalent). Clinical fellows with the title instructor are allowed as long as they are no more than 5 years into their training similar to above bullet concerning postdoctoral training.
• Must be able to devote at least 75% of full-time effort to breast cancer research and activities, i.e., protected research time.
• Applicant/PI may not hold another career transition award, training award (K-type awards) or R-type award at time of notification of intent to fund (on or around April 15, 2025). If Applicant previously held an R-type award at any point, they are not eligible to apply for this award.
• Is not required to be a U.S. citizen or permanent resident.

*The University of Arizona Cancer Center (UACC) can nominate up to two applicants but only if at least one of the two nominees identifies as as someone from groups shown to be historically minoritized and marginalized in biomedical research from National Science Foundation data (details outlined in RFA).

For more information please contact UACC-preaward@arizona.edu


Apply to Internal Competition // Limit: 2 // Tickets Available: 2*

Limit: 1 // K. Rhodes  (Immunology)

The funds are designed to provide to tenure track faculty members in their first to fourth year, at American Institutions, who hold M.D. and/or Ph.D. degrees, start-up support to move the project forward to the point where R01 or other independent funding can be obtained.  Applicants with current R01 funding should not apply.

Beginning in 2023, the grant provides $75,000 annually for a period of up to three years.  Grants are not renewable.  Institutions may submit one proposal per session.  Interested candidates should work through their sponsored projects office.

Proposals must contain an adequately detailed description of the project to be clearly understandable by the scientific members of the Trustees.  They need not be in the detail requested by the NIH for R01 grants and should not exceed five pages in length.  Additional material can be submitted, but the five-page application should contain the essential information.  References should also be included to support the proposal.  Note that the five page limit is only for the project description.  

A one-two page lay summary must be provided as part of the proposal. Applicants should bear in mind that our Board includes non-scientist members, making this summary of particular importance.  The summary should include the project’s title, and the investigator's contact information.

In addition to the institution providing recognition of an internal selection process resulting in no more than one candidate, (this requires just a sentence that may be included in the letters), the proposal must be accompanied by letters of approval by the Dean of the medical school and/or another senior faculty member or members who can represent the support of the institution and who are acquainted with the qualifications of the applicant and the potential impact of his/her work.

Limit: 1 // K. Rhodes  (Immunology)

The funds are designed to provide to tenure track faculty members in their first to fourth year, at American Institutions, who hold M.D. and/or Ph.D. degrees, start-up support to move the project forward to the point where R01 or other independent funding can be obtained.  Applicants with current R01 funding should not apply.

Beginning in 2023, the grant provides $75,000 annually for a period of up to three years.  Grants are not renewable.  Institutions may submit one proposal per session.  Interested candidates should work through their sponsored projects office.

Proposals must contain an adequately detailed description of the project to be clearly understandable by the scientific members of the Trustees.  They need not be in the detail requested by the NIH for R01 grants and should not exceed five pages in length.  Additional material can be submitted, but the five-page application should contain the essential information.  References should also be included to support the proposal.  Note that the five page limit is only for the project description.  

A one-two page lay summary must be provided as part of the proposal. Applicants should bear in mind that our Board includes non-scientist members, making this summary of particular importance.  The summary should include the project’s title, and the investigator's contact information.

In addition to the institution providing recognition of an internal selection process resulting in no more than one candidate, (this requires just a sentence that may be included in the letters), the proposal must be accompanied by letters of approval by the Dean of the medical school and/or another senior faculty member or members who can represent the support of the institution and who are acquainted with the qualifications of the applicant and the potential impact of his/her work.

Limit: 1 // Next funding cycle August 1st, 2025*

Due to an update in the guidelines, the foundation will not accept proposals during 2024. If still eligible, the PI selected for 2024 will be submitted during 2025.

PI Selected: K. Rhodes  (Immunology)

The funds are designed to provide to tenure track faculty members in their first to fourth year, at American Institutions, who hold M.D. and/or Ph.D. degrees, start-up support to move the project forward to the point where R01 or other independent funding can be obtained.  Applicants with current R01 funding should not apply.

Beginning in 2023, the grant provides $75,000 annually for a period of up to three years.  Grants are not renewable.  Institutions may submit one proposal per session.  Interested candidates should work through their sponsored projects office.

Proposals must contain an adequately detailed description of the project to be clearly understandable by the scientific members of the Trustees.  They need not be in the detail requested by the NIH for R01 grants and should not exceed five pages in length.  Additional material can be submitted, but the five-page application should contain the essential information.  References should also be included to support the proposal.  Note that the five page limit is only for the project description.  

A one-two page lay summary must be provided as part of the proposal. Applicants should bear in mind that our Board includes non-scientist members, making this summary of particular importance.  The summary should include the project’s title, and the investigator's contact information.

In addition to the institution providing recognition of an internal selection process resulting in no more than one candidate, (this requires just a sentence that may be included in the letters), the proposal must be accompanied by letters of approval by the Dean of the medical school and/or another senior faculty member or members who can represent the support of the institution and who are acquainted with the qualifications of the applicant and the potential impact of his/her work.

Limit: 1 // Tickets Available: 0

G. Melandri (Plant Sciences) 
 

Institutions may submit one nominee to the 2025 New Innovator Award program.
 

The New Innovator in Food & Agriculture Research Award provides early-career scientists the investment needed to propel them into successful research careers.
Young faculty in the sciences often struggle to secure grant funding. We established the New Innovator Awards to launch the careers of promising scientists whose research addresses significant food and agriculture challenges. These awards allow the grantees to focus exclusively on research without the pressure of securing additional funding.

 Eligible Individuals

Faculty members at eligible institutions with the creative ideas, skills, knowledge and resources necessary to carry out the proposed research program as principal investigator are invited to work with their institution to develop an application for support.

• The nominated faculty member must have been hired on or after August 1, 2021 for a tenure-track or equivalent position and may work in any discipline or any department within the institution.
• Preference will be given to individuals near the onset of their independent research career and who are within eight (8) yearsof receiving a Ph.D. or equivalent degree.
• Individuals with significant research experience prior to obtaining their faculty position will not be considered for this award. For the purpose of this funding opportunity, significant research experience is defined as a nominee that has been awarded a substantial research grant (three to five years of support) or has received project funding totaling over $1M within the time of their tenure position or has been awarded similar career development awards with similar budgetary scopes.
• This research concept must directly benefit U.S. agricultural interests.

FFAR recognizes that agriculture and food sciences are highly complex, requiring individuals from a variety of disciplines to realize the potential in each field or research area. Particularly for early-stage investigators, collaborators are often essential for success. While this award is made to an outstanding early career investigator, applicants should include information regarding any essential collaborators and include letters of support from those collaborators. In these letters, the collaborators should comment on the potential of the individual to achieve success.

Limit: 2 // Tickets Available: 2

Only two applications per institution (normally identified by having a Unique Entity Identifier (UEI) number or NIH IPF number) are allowed.

The NIH Director's Early Independence Award supports rigorous and promising investigators who wish to pursue independent research soon after completion of their terminal doctoral degree or post-graduate clinical training, thereby forgoing the traditional post-doctoral training period and accelerating their entry into an independent research career. To support innovative and novel research across the vast NIH mission, individuals from diverse backgrounds (including those from underrepresented groups; see Notice of NIH’s Interest in Diversity) and from the full spectrum of eligible institutions in all geographic locations are encouraged to apply. Applications in all topics relevant to the broad mission of NIH are welcome, including, but not limited to, topics in the behavioral, social, biomedical, applied, and formal sciences and topics that may involve basic, translational, or clinical research. The NIH Director's Early Independence Award is a component of the High-Risk, High-Reward Research program of the NIH Common Fund.

Requirements:

• Single PD/PI: Only single PD/PI applications are allowed. Multiple PD/PIs applications will not be accepted. Only the PD/PI may be listed as a Senior/Key Person and provide a Biographical Sketch.
• Citizenship: U.S. citizenship is not required. For non-U.S. citizens, the applicant institution is responsible for ensuring the PD/PI's U.S. visa status will allow them to conduct the proposed research at the applicant institution for the entire project period.
• Degree Receipt Date: The receipt date of the PD/PI’s terminal doctoral degree or end of post-graduate clinical training must be between May 1, 2023, and September 30, 2025. The degree receipt date is that which appears on the official transcript for the degree. The end of post-graduate clinical training includes residency and fellowship periods. At the time of award, either:

1. The PD/PI must have received a PhD, MD, DO, DC, DDS, DVM, OD, DPM, ScD, EngD, DrPH, DNSc, ND (Doctor of Naturopathy), PharmD, DSW, PsyD, or equivalent doctoral degree from an accredited domestic or foreign institution (it is the responsibility of the sponsoring institution to determine if a foreign doctoral degree is equivalent).
2. Or an authorized official of the degree-granting or training institution must certify that all degree requirements have been met and that the receipt date of the degree (as will appear on the transcript) will be before September 30, 2025. An authorized official of the host institution must certify that the PD/PI will be able to conduct independent research at the institution at the time of the project start date.

• Post-doctoral Experience: The PD/PI must not have served as a post-doctoral fellow for more than 12 months following a previous, non-terminal doctoral degree (this only applies to PD/PIs with multiple doctoral degrees who served in a 12+ month post-doctoral fellowship before their terminal degree).
• Level of Effort: In the first and second years of the project period, the PD/PI must commit at least 9.6 person-months of effort to the Early Independence Award project each year (80% effort per year). In years 3-5 of the project period, the PD/PI may reduce their effort on the Early Independence Award project but must still conduct at least 9.6 person-months of general independent research each year (80% effort per year). General independent research includes the effort spent on the Early Independence Award project and any other independent research projects the PD/PI is working on.
• Non-independence at Time of Application: Individuals are eligible only if they do not have research independence at the time of application submission. Research non-independence is defined functionally rather than by position title and must have all the following characteristics:
  1. The PD/PI's current research agenda is set through concurrence with mentors.
  2. The PD/PI's research is funded primarily through support to other investigators (mentored fellowships such as NIH F31 or F32 Fellowships or NSF Graduate Research Fellowships do not preclude eligibility).
  3. The PD/PI does not have any space assigned directly by the institution for the conduct of their research.
  4. The PD/PI cannot apply for an NIH R01 grant without a special waiver or exemption from the institution according to institutional policy.

Though PD/PIs must not be functionally independent at the time of application submission, they may become functionally independent prior to time of award and still retain eligibility.

• Independent Research Position: An independent research position at a host institution is required, and the PD/PI must be able to begin independent research by the project start date. The position need not be permanent or tenure-track and may be contingent upon receipt of the Early Independence Award. Prospective PD/PIs should contact appropriate institutional leaders to seek an appointment to an independent research position. Alternatively, institutions may actively recruit eligible scientists to apply for support through this initiative. In either case, the institution is expected to provide substantial support to the PD/PI as detailed in the Facilities & Other Resources section. To foster independence, PD/PIs may benefit from being hosted by an institution at which they have not previously studied or trained.
• Career Awards: PD/PIs may apply for a research career development (K) award and DP5 at the same time, but NIH policy prohibits scientific overlap. A PD/PI may not hold a DP5 and career development award concurrently: The career development award must be relinquished to receive the DP5.
• Site Visit: NIH staff will conduct a one-time site visit at the end of the first year to assess the PD/PI's progress and to ensure they are receiving the institutional resources and support outlined in the application. NIH staff will meet with the PD/PI, lab personnel, mentors, faculty, and institutional leadership. Failure to provide independence and/or support may lead to NIH actions, including reduction of funds.

Awards will be for up to $250,000 in direct costs per year, plus applicable Facilities and Administrative (F&A) costs.

Limit: 1 // A. Favela (School of Plant Science)

Due to the competitive nature of this funding program, this selection process is running with an anticipated deadline.
We will keep all applicants informed of relevant updates in the guidelines, submission deadlines, and eligibility as soon as more information becomes available.

The Searle Scholars Program supports research of outstanding individuals who have recently begun their appointment at the assistant professor level, and whose appointment is their first tenure-track position at a participating academic or research institution. Today, 168 institutions are invited to participate in the Program.

The Program was established at The Chicago Community Trust in 1980 and has been administered by Kinship Foundation since 1996. The Program is funded from the estates of Mr. and Mrs. John G. Searle. Mr. Searle was the grandson of the founder of the world-wide pharmaceutical company, G.D. Searle & Company. It was Mr. Searle's wish that certain funds be used to support "...research in medicine, chemistry, and the biological sciences."

Each year 15 new individuals are named Searle Scholars. Awards are currently set at $100,000 per year for three years. Since its inception, 617 Scholars have been named and over $174 million has been awarded.

The Searle Scholars Program Scientific Advisory Board is primarily interested in the potential of applicants to make innovative and high-impact contributions to research over an extended period of time.

Applicants for the 2025 competition (awards which will be activated on July 1, 2025) are expected to be pursuing independent research careers in biochemistry, cell biology, genetics, immunology, neuroscience, pharmacology, and related areas in chemistry, medicine, and the biological sciences.

Applicants should have begun their appointment as an independent investigator at the assistant professor level on or after July 1, 2023. The appointment must be their first tenure-track position (or its nearest equivalent) at an invited institution.

Institutions which do not have tenure-track appointments should consult with the Scientific Director of the Program regarding eligibility of selected applicants PRIOR to nominating such individuals.

The Searle Scholars Program does not ordinarily support purely clinical research but has supported research programs that include both clinical and basic components. Potential applicants who are unsure if their research is appropriate for our Program are encouraged to examine the research interests of present and former Searle Scholars on this website.

Applicants who were nominated for awards in the previous competition year but were not awarded may still meet the eligibility criteria for the current competition. Institutions should consult with the Scientific Director of the Program regarding renomination of such individuals.

The Searle Scholars Program Scientific Advisory Board is primarily interested in the potential of applicants to make innovative and high-impact contributions to research over an extended period of time.

Amount per Award: $300,000
Duration of Award: 3 Years

No Applicants // Limit: 2* // Tickets Available: 2

Starting in 2024, ADA will accept up to two (2) nominations per institution with one (1) nomination spanning basic through preclinical research and one (1) nomination spanning clinical through public health research. 

Pathway to Stop Diabetes has a simple, yet revolutionary goal: to find scientists at the peak of their creativity and provide them with the flexibility and resources they need on the road to breakthrough discoveries. We attract and retain brilliant scientists in diabetes. Our three areas of focus—awarding research grants, providing access to scientific and career mentoring from leading diabetes researchers, and creating a diabetes think tank—are each key components of a unique formula to cultivate the next generation of leaders, whose discoveries will stop diabetes and all of its burdens once and for all.

Initiator Award (INI)

• Award Term: Up to 7 years
• Applicant: Postdoctoral Fellow
• Maximum Funding: Up to $100,000/year in Phase 1, Up to $325,000/year in Phase 2
• Support: Project support & PI salary
• Indirect Support: Up to 10% of directs in Phase 1, Up to 30% of directs in Phase 2
• Project % Effort Required: 75-100% effort in Phase 1, 50-75% effort in Phase 2
• Citizenship: Authorized to work in U.S. or U.S. possessions
• Description: This two-phased award is designed to support the transition of scientists from mentored training to independent research faculty.
• Eligibility: Eligible applicants must currently be in research training positions (post-doctoral fellow, research fellowship) and have no more than seven years of research training following terminal doctoral degree. Applicants cannot concurrently hold an NIH K99/R00 grant. Candidates must be identified through institutional nomination; applications will be accepted only from individuals with the appropriate institution support.
• Support: Awards provide two distinct phases of research support: Phase 1 provides up to two years of support for mentored training at a maximum of $100,000 per year (including 10% indirect costs), Phase 2 provides up to five years of support for independent research at a maximum of $325,000 per year (including 30% indirect costs). Maximum combined support for Phase 1 and Phase 2 is $1,625,000.

Accelerator Award (ACE)
 

• Award Term: Up to 5 years
• Applicant: Early Career Faculty
• Maximum Funding: $325,000/year
• Support: Project support & PI salary
• Indirect Support: Up to 30% of directs
• Project % Effort Required: 25-50% effort
• Citizenship: Authorized to work in U.S. or U.S. possessions
• Description: This award is designed to support exceptional, independent early-career researchers who have distinguished themselves as promising investigators and are in the beginning stages of establishing successful, sustainable diabetes research programs.
• Eligibility: Awards are available to early-career diabetes investigators proposing innovative and ambitious diabetes-related research programs. Applicants must hold faculty positions and have demonstrated independent productivity in diabetes research. Applicants may currently hold independent NIH funding (K, U or R awards, including an initial R01/U01) but must not have applied for (regardless of outcome), or received, an R01/U01 renewal or a second R01/U01 award. Candidates must be identified through institutional nomination; applications will be accepted only from individuals with the appropriate institution support.
• Support: Awards provide five years of research support at a maximum of $325,000 per year (including 30% indirect costs), for a total of $1,625,000.