These foundational principles guide quality management across all University of Arizona research units Subject Protection Prioritize the rights, safety and well-being of research participants in all study designs and implementation. Data Quality Ensure data accuracy, completeness, consistency and traceability through standard collection and management procedures Regulatory Compliance Ensures adherence to all applicable federal, state, local, and institutional regulations governing research conduct. Risk Based Approach Implement quality measures proportionate to the risk level of research activities, focusing resources on critical quality factors. Integrity and Transparency Maintain honest, accurate and complete documentation in all research activities with transparent reporting of findings and limitations. Continuous Improvement Foster a culture of ongoing learning and improvement through regular assessment, feedback and implementation of best practices