Research

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Limiting Language
An institution may submit only one Center (and related Projects) application in response to this RFP.

Purpose
The intent of this initiative is to support a collaborative network of researchers whose collective efforts will lead to enhanced understanding of the earlier detection and/or delaying progression of valvular heart disease. Therefore, this Request for Proposals seeks applications that can address these critical questions and stimulate significant advances in these areas of valvular heart disease. All proposed projects must address valvular heart disease. Within that context and as presented above, an array of potential areas of investigation exists. Both human studies and appropriately designed animal models that can foster understanding of valvular heart disease may be proposed. 

STUDY POPULATION(S)

• For studies involving human subjects, researchers must ensure that participant populations accurately reflect those affected by the disease under investigation. Efforts should be made to include individuals whose health criteria align with the prevalence and impact of the disease, thereby enhancing the relevance and applicability of the study findings.
  
   
• Important: Applicants should design studies that incorporate both realistic recruitment goals and sufficient statistical power to ensure valid results.

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Z. Chen (College of Public Health)

Limiting Language
Organizations may submit only one Letter of Inquiry per deadline. Common exceptions include LOIs submitted by separate departments of large universities.

Overview
RRF funds research that seeks to identify interventions, policies and practices to improve the well-being of older adults and/or their caregivers. Preference is given to projects aimed at generating practical knowledge and guidance that can be used by advocates, policy-makers, providers, and the aging network. Of particular interest are:

• Interventional trials; translational studies; and health services and policy research
• Projects that build on the investigator’s past studies
• Proposals that include robust dissemination plans, if appropriate, to assure that findings reach audiences positioned to act on them

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Limiting Language
BRF will only accept one LOI per institution

Overview
Brain Research Foundation’s Annual Seed Grant Program was initiated in 1981. The purpose of our program is to provide start-up monies for new research projects in the field of neuroscience that will likely lead to extramural funding from the National Institutes of Health (NIH) or other outside funding sources. 

The objective of the BRF Seed Grant Program is to support new and innovative projects, especially those of junior faculty, who are working in new research directions. BRF Seed Grant awards are not intended to supplement existing grants

Funding Specifics
1.) Funding is to be directed at pilot research projects that are both innovative and will likely lead to successful grant applications to NIH and other public and private funding entities. 

2.) Assistant Professor – Junior faculty with a new research project that will generate pilot data that will lead to RO1 funding or a comparable outside grant will be first priority. • Must provide abstract and specific aims for current grants and indicate if there is any overlap. 

3.) Associate Professor – Faculty who are pursuing new research directions. • Must explain how the project is a new research direction. • Must provide abstract and specific aims for current grant(s) and indicate if there is any overlap. 

4.) A new technique is not considered a new direction unless it pertains to a different area of study. 

5.) Grants are NOT to be used for bridge funding between grants. 

For full guidelines, please visit https://www.thebrf.org/seed-grants/ 

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M. Beidaghi (Aerospace and Mechanical Engineering)

Limiting Language
An institution may submit only a single proposal in response to this solicitation, as the lead institution.

If more than one proposal is submitted from an institution, the first proposal submitted from that institution will be considered, and remaining proposals will be returned without review.

An institution may serve as a non-lead institution on more than one proposal.

Synopsis of Program
Autonomous experimentation is poised to accelerate research and unlock critical scientific advances that bolster U.S. competitiveness and address pressing societal needs. Programmable Cloud Laboratories are able to execute automated workstreams, including self-driving lab workflows, to efficiently move research goals through artificial intelligence (AI) enabled experiment design, laboratory preparations, data collection, data analysis and interpretation. While limited-scale efforts have shown promise, versatile programmable and self-driving labs capable of addressing complex research questions with trustworthy results will require coordinated technological advances and an engaged research community. Additional challenges include the availability of automated laboratory infrastructure, standardized approaches to data collection for interoperability, advances in AI for data interpretation and experimental design, and more. This solicitation aims to address such gaps and realize the potential of autonomous experimentation.

The Test Bed: Toward a Network of Programmable Cloud Laboratories (PCL Test Bed) program seeks to establish and facilitate the operation of distributed autonomous laboratory facilities. These laboratories will combine technological and human capacity to enable integration, testing, evaluation, validation, and translation of cutting-edge technology solutions in automated science and engineering. The PCL Test Bed will consist of a set of Programmable Cloud Laboratory Nodes (PCL Nodes) that can be remotely accessed to run custom workflows specified and programmed by users, that are linked together via computational networking, shared science questions, and data and artificial intelligence (AI) standards.

The PCL Test Bed will facilitate access to advanced scientific equipment, accelerate translation and scaling of basic research into industry applications, enhance reproducibility and the exchange of experimental data, and assist in training the next generation of scientists and engineers in state-of-the art methodologies. It will help develop community norms, best practices, and formal standards for automated laboratory procedures, workflows, and instrument testing and validation. It will also advance consistent practices for the collection, sharing, and use of metadata and training data and the use and exploitation of AI methods. This program will also support the development of automated laboratory methods, including self-driving autonomous experiment workflows.

Proposals must have a set of well-defined science drivers poised to derive significant benefit from targeted use of the PCL Test Bed capabilities, including but not limited to synthesis, optimization, and/or characterization experiments, in specific sub-disciplines within materials science, biotechnology, chemistry or other areas of science and engineering. These science drivers will guide the protocols and standards necessary for each node and facilitate collaboration across the Test Bed. For example, science drivers could include but are not limited to:

• Materials science, materials synthesis and characterization efforts that advance U.S. competitiveness.
• Biotechnology experiments in scalable, high-throughput engineering and characterization services for proteins or microbes with novel applications in the U.S. bioeconomy.
• High-throughput experimentation for the accelerated development of catalysts to support more efficient chemical synthesis to address urgent national needs.

User Recruitment and On-Boarding Workshops will be a key component of the PCL Test Bed program and will serve to recruit users to individual PCL Nodes and the Test Bed to help make progress on the proposed science drivers, provide access to technology, test the limits of the experimental set-up of the nodes, and explore new research opportunities between the PCL Nodes and institutions including, but not limited to, R2 Universities, PUI (Primarily Undergraduate Institutions), and two-year institutions.

The PCL Test Bed will be available to researchers in academia as well as industry, including current and former awardees from the Small Business Innovation Research/Small Business Technology Transfer (SBIR/STTR) programs. The portfolio of projects is available here, https://seedfund.nsf.gov/portfolio.

PCL Nodes are expected to develop and implement plans for continued operation after the period of this award.

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Limiting Language
Only one applicant from a university or non-profit research institute will be considered in each application cycle. Institutions should have an internal screening and selection process, as the Foundation will not consider multiple letters of intent received from a single institution. For purposes of this limitation, the Foundation considers the overseeing university to be the institution. Thus, a university with a law school, medical school, several teaching hospitals, and a faculty of arts and sciences may only submit one application in total. If a university system, such as a state-wide university system, comprises several universities, each university within the system may nominate one applicant.

Program Overview
The Greenwall Faculty Scholars Program in Bioethics is a career development award to enable early-career faculty members to carry out innovative bioethics research. It supports research that goes beyond current work in bioethics to help resolve pressing ethical issues in clinical, biomedical, and public health decision-making, policy, and practice, and creates a community that enhances future bioethics research by Scholars and Alums.

Each year, the Foundation selects approximately three Greenwall Faculty Scholars to receive 50 percent salary support for three years to enable them to carry out a specific research proposal and develop their research program.

Scholars and Alums attend twice-yearly meetings, where they present their works in progress, receive feedback and mentoring from the Faculty Scholars Program Committee and other Scholars and Alums, and have the opportunity to develop collaborations with other researchers. Third-year Scholars are expected to help plan these meetings. Ongoing involvement of Alums with the Program provides continued opportunities for professional development and feedback, and engages them in mentoring of early-career Scholars. In addition, all first-year Scholars participate in a philosophical bioethics seminar series; additional professional development opportunities may also be offered.

The Program Committee provides oversight and direction for the Program and is involved not only with selection of the Scholars but also with mentoring and professional development activities. 
 

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A.J. Scott (COM-T)

The University of Arizona Cancer Center (UACC) is coordinating this limited submission. For more information please contact: UACC-PreAward.

Limiting Language
Applications are limited to four per institution per receipt date including new (A0), resubmissions (A1) and renewal (T2); NCI-designated cancer center consortia are considered one institution. NCI seeks a broad representation of institutions for this award mechanism and may take this into account when making funding decisions.

Purpose
Through this notice of funding opportunity (NOFO), the National Cancer Institute (NCI) invites applications for the Research Specialist Award in any area of NCI-funded clinical cancer research. This NOFO is specifically for clinician scientists to continue to participate in the NCI clinical trials networks through leadership in the 1) development of national clinical trials, 2) implementation of NCI clinical trials in their institutions, and 3) national service to the NCI clinical trials networks through participation in the scientific review committees, monitoring committees, and other activities, but not serve as principal investigators of research project grants. These clinician scientists are vital to sustaining the NCI-funded clinical trials enterprise. The Research Specialist Award is intended to provide stable support for clinician scientists at their institutions for significant leadership and exceptional participation in the NCI-sponsored clinical trials networks that conduct cancer treatment, prevention and control, and care delivery clinical trials. NCI-sponsored clinical trials networks include but are not limited to the National Clinical Trials Network (NCTN), the NCI Community Oncology Research Program (NCORP), the Experimental Therapeutics Clinical Trials Network (ETCTN), and the Cancer Prevention Clinical Trials Network (CP-CTNet).

The Research Specialist Award is designed to encourage the development of a career path for cancer clinical trial investigators who provide leadership, participation, and scientific support for the NCI clinical trials networks at their institutions and within those networks. This leadership includes the development of concepts and protocols for clinical trials, participation in scientific steering committees and network committees, and accrual to NCI-sponsored clinical trials. The institutional activities may include the implementation of cancer clinical trials including participation in the review of safety data, monitoring the conduct and progress of open clinical trials, and serving on institutional review committees. These activities are necessary for the successful conduct of NCI-sponsored cancer clinical trials. The Research Specialist Award is intended to provide salary support and sufficient autonomy so that individuals are not solely dependent on NCI grants held by others or other sources of funding for cancer research career continuity.

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L. O'Neill - (Center on Aging)

Limiting Language
My organization is a government, a tribal entity, or a university: You may submit one application per department. You may submit another if, and only if, you are collaborating with another organization.  
o If you would like to submit a second application on behalf of a collaborative group of organizations, submit only one application per project. This means choosing just one organization to submit the collaborative application.  
o If several departments are applying for the same project, please treat it as a collaborative application. 
o A government or tribal agency, or university may apply for projects separate from those the individual departments apply for.   

Grant Description
All organizations requesting grants must provide services that directly benefit populations residing in Cochise County and eastern Santa Cruz Counties. 

The Legacy Foundation of Southeast Arizona is seeking applications for Innovative grants.  

Grant Cycle – June 2, 2025 through September 26, 2025. Awards will be announced by December 13, 2025.  Grants will be awarded January 2026.  

Every year the Legacy Foundation of Southeast Arizona funds Innovation Grants for projects up to $50,000 that are aligned with the Foundation Mission of Promoting Population Health and Community Wellness. 

Collaboration and forging partnerships with other community organizations are key determinants in funding decisions. 

The Legacy Foundation of Southeast Arizona will kick off the Innovative Grant Cycle with a workshop that will provide full information regarding the goals of the cycle. 
 

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O. Zhupanska (Aerospace and Mechanical Engineering)
M. Krunz (Electrical and Computer Engineering)
B. Revil-Baudard (Materials and Science Engineering)

Limiting Language:

Each PPP is limited to a maximum of four PIs. No university shall exceed leading three PPPs. Candidate must be a University Consortium Member prior to submitting a Notice of Intent (NOI)

Topics: 

1. TOPIC 1: IMPROVED SUB-SCALE HYPERSONIC AIR-BREATHING PROPULSION TEST CAPABILITIES  
2. TOPIC 2: DIGITAL TWIN ARCHITECTURE FOR HYPERSONIC AIR-BREATHING SYSTEM AND MISSION DESIGN TRADE STUDIES
3. TOPIC 3: SHOCK PROPERTIES OF ADDITIVELY MANUFACTURED MATERIALS (AMM)
4. TOPIC 4: EXPERIMENTAL & MODEL BASED ENDOTHERMIC FUEL PROPERTIES
5. TOPIC 5: CERAMIC TESTING FOR HYPERSONIC VEHICLES
6. TOPIC 6: MITIGATION OF THERMAL DEGRADATION IN HYPERSONIC WINDOWS
7. TOPIC 7: NETWORKING AND COLLABORATIVE COMMUNICATIONS 

Questions regarding the Project Call may be emailed to UCAH@tamu.edu through September 5, 2025 at 5:00 PM EST. Answers to the questions will be posted on the UCAH website for this RPP Project Call. All questions and answers will be made available to all proposers, unless they involve proprietary or CUI material. 

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Limiting Language
Applicants must be approved by their department to apply for the PBF Fellowship. Institutions may have no more than three Parker B. Francis Fellows in a single department at a given time, a department may submit nor more than two applications annually, and a mentor may sponsor only one application annually.

Executive Summary
The Parker B. Francis Fellowship provides research support to clinical and basic scientists embarking on careers in clinical, laboratory or translational science related to Pulmonary, Critical Care and Sleep Medicine at a U.S. or Canadian university or research institution. The ideal candidate is one with evidence of strong aptitude in research and who is in transition from post-doctoral trainee to independent investigator. It is essential that there be evidence of accomplishment and proficiency in research. Few applicants who are just beginning research training and have only one or two research publications are funded.

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K. Huntoon (Neurosurgery)

Goal and Focus  

The goal of these grants is to overcome barriers to the clinical application of new treatment approaches for childhood cancer. A priority is to fund projects that have already shown great promise, but that have a specific funding need to move forward. 

The three main focus areas for this RFP are:  

• Cancer immunotherapy or targeted therapy  

• High-grade brain tumors or other difficult-to-treat pediatric cancers  

• Epigenetic modifying therapy or gene therapy  Applications of novel technologies (e.g. nanotechnology, omics, gene editing, bioinformatics, and AI) in these areas are welcome. 

Eligibility  

• Applications will only be accepted from Children’s Oncology Group member institutions in North  America (no citizenship requirements).  

• Open to PIs at all academic ranks with MD and/or PhD  

• Limit of one application per institution for either the Collaborative or the Individual grant with the  endorsement of the Chief(s) of the Division(s) of Pediatric Hematology-Oncology.