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International Religious Freedom Fund (I-REFF) Emergency Assistance

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Limiting Language
Primary applicants may submit one application in response to this NOFO.

Executive Summary 
The U.S. Department of State, Bureau of Democracy Human Rights and Labor,
Office of International Religious Freedom (IRF) announces an open competition
for organizations interested in submitting applications for a program to provide
emergency financial assistance to victims of religious persecution and defenders of religious freedom.

IRF promotes religious freedom as a core objective of U.S. foreign policy that
makes America stronger, safer, and more prosperous. IRF’s mission is guided by
its statutory mandate established by the International Religious Freedom Act of
1998 (IRF Act) and the Frank Wolf International Religious Freedom Act of 2016
(Wolf Act). The IRF Act provides that it is the policy of the United States,
“standing for liberty and standing with the persecuted, to...promote respect for
religious freedom by all governments and peoples.” To that end, the Wolf Act calls
for the State Department to issue foreign assistance awards to promote respect for
religious freedom and combat religious freedom violations.

As declared in President Trump’s Executive Order 13926, the promotion of
international religious freedom is a “national security imperative” and “a foreign
policy priority of the United States.” Pursuant to that Executive Order, IRF funds
foreign assistance programs to “anticipate, prevent, and respond to attacks against
individuals and groups on the basis of their religion, including programs designed
to help ensure that such groups can persevere as distinct communities; to promote
accountability for the perpetrators of such attacks; to ensure equal rights and legal
protections for individuals and groups regardless of belief; to improve the safety
and security of houses of worship and public spaces for all faiths; and to protect
and preserve the cultural heritages of religious communities.”

Information on religious freedom conditions globally can be found in the State
Department’s annual International Religious Freedom Report.

Applicants will be responsible for ensuring program activities and products are
implemented in accordance with the Establishment Clause of the United States
Constitution. 

Funding Type
Internal Deadline
External Deadline
3/16/2026
Solicitation Type

American Heart Association Heart Transplant Research Network

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Limiting Language
An institution may submit only one application in response to this RFP.  

Background
The first heart transplant was performed in 1967, one of the most extraordinary feats of modern medicine. The system that supports it, however, has failed to evolve significantly since then, with none of the astonishing novel therapies we see being developed in other areas of medicine. Despite decades of innovation in almost all the other cardiovascular spheres, heart transplant care remains fragmented, inequitable, and frustratingly stagnant. Patients face ongoing cardiac rejection with imprecise methods to detect the immunologic process, potentially toxic immunosuppressive regimens which have not been updated substantially for two decades, and inconsistent outcomes—especially among Black recipients and pediatric populations. Data are siloed, research is underfunded, and quality improvement is virtually nonexistent. The majority of clinical practice guideline recommendations are driven by consensus rather than an evolving catalog of evidence. 

There is no unified national data infrastructure that can support retrospective and prospective research, no standardized quality improvement framework, and no coordinated research agenda to address these challenges. In short, we are crawling in one of the most high-stakes areas of healthcare. 

The American Heart Association is launching a bold, multi-phase initiative to transform heart transplantation care across the United States, a transformation in treatment built on three pillars: 

  • A Global Heart Transplant Data Infrastructure In collaboration with key transplant organizations, the American Heart Association will manage a comprehensive heart transplant database, designed not as a static registry, but as a dynamic, harmonized data platform to drive research, quality improvement, and policy change.
  • A Research Network for Breakthrough Science We are now recruiting from leading institutions to launch a research network focused on rejection detection, remote monitoring, viral load surveillance, and innovative, safer therapies. This network will be the sandbox for high-impact studies, including planning grants for clinical trials in immune tolerance, and chronic rejection.
  • A Quality Improvement Infrastructure Modeled after our Get With The Guidelines® success, we will build a scalable Quality Improvement (QI) framework to standardize transplant care, reduce disparities, and improve long-term outcomes. This will drive system-wide change. 
Funding Type
Internal Deadline
External Deadline
3/10/2026
Solicitation Type

CTR Non-Proliferation Programing

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Limiting Language
Applicants can submit one application in response to the NOFO.  If more than one application is submitted by an organization, only the final application received, and time stamped by grants.gov will be reviewed for eligibility.  Each application can include multiple projects that will be evaluated independently.  

Executive Summary
Priority of Regions:

  1. Western Hemisphere (WHA)
  2. East Asia and the Pacific (EAP)
  3. South and Central Asian (SCA)
  4. Europe and Eurasia (EUR)
  5. Middle East and North Africa (NEA)
  6. Africa (AF)

The Office of Cooperative Threat Reduction (CTR) is a key component of the Department’s and ACN’s efforts to advance the Administration’s top national security and foreign policy objectives in a cost-effective and impactful manner.  CTR uses programming and training with foreign partners to advance President Trump’s America First Investment Policy (NSPM-3) and America’s AI Action plan by disrupting the Chinese Communist Party’s (CCP) exploitation of critical U.S. intellectual property (IP) and dual-use technologies, including AI, biotechnologies, quantum, semiconductor, and space technologies, through research security, cybersecurity and IP protection training.  As the programmatic lead for the Foundational Infrastructure for the Responsible Use of Small Modular Reactor [SMR] Technology (FIRST) program, CTR implements Section 8(e) of EO 14299 on Deploying Advanced Nuclear Reactor Technologies for National Security by helping U.S. vendors deploy secure, safe U.S. SMRs to strategic regions, including Latin America, the Indo-Pacific, and the Middle East, to outcompete strategic competitors for decades-long partnerships, generating multi-billion dollar deals for U.S. companies and creating thousands of American jobs.  CTR implements maximum pressure on Iran (NSPM-2), by training foreign partner countries to implement U.S. sanctions on Iran’s nuclear weapons and ballistic missile programs, and disrupts proliferation networks tied to the CCP, DPRK, and Russia that undermine U.S. interests.  CTR also advances EO 14292 by preventing U.S. adversaries from advancing biological weapons capabilities through targeted biosecurity, physical security, and cybersecurity trainings and disrupts Iran’s and other U.S. adversary chemical weapons programs through assisting supply chain security of precursor chemicals and equipment. Finally, CTR advances EO 14285 Unleashing America’s Offshore Critical Minerals, by training critical mineral holders to derisk from reliance on Chinese and Russian Private Military Companies in favor of U.S. security firms.

Research Category
Funding Type
Internal Deadline
External Deadline
3/6/2026
Solicitation Type

2026 Library of Congress Literacy Awards

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Limiting Langauge 
Each organization may only submit one application in any given year. Applicants must decide whether they are eligible for the Top Prize Awards (Rubenstein, Kislak, American or International), or the Emerging Strategies Honorees category and choose the correct application form accordingly.

Prize Category Descriptions

  • The David M. Rubenstein Prize ($150,000) is awarded to an organization, based either inside or outside the United States, which has demonstrated exceptional and sustained depth in its commitment to the advancement of literacy. The organization meets the highest standards of excellence in its operations and services. Applicants should complete the Top Prize Application Question Form for consideration for this prize.
  • The Kislak Family Foundation Prize ($100,000) is awarded to an organization, based either inside or outside the United States, with an outsized impact on literacy relative to its size and/or years of operation. Applicants should complete the Top Prize Application Question Form for consideration for this prize.
  • The American Prize ($50,000) is awarded to an organization based inside the United States for making a significant and measurable contribution to increasing literacy levels in the U.S. or the national awareness of the importance of literacy. Applicants should complete the Top Prize Application Question Form for consideration for this prize.
  • The International Prize ($50,000) is awarded to an organization that is based either inside or outside the United States for their significant and measurable contribution to increasing literacy levels in a country other than the U.S. Applicants should complete the Top Prize Application Question Form for consideration for this prize.
  • Successful Practices Honorees ($10,000/organization; up to 15 organizations) are recognized for their successful implementation of a specific literacy practice. NOTE: all applicants are automatically considered for the Successful Practices Honoree recognition. Applicants who complete the Top Prize Application Question Form will automatically be considered for this prize.
  • Emerging Strategies Honorees ($5,000/organization; up to 5 organizations) are recognized for a literacy initiative in its early stages of development (5 years or fewer) that demonstrate significant creativity and promise in their approach to promoting literacy. For the 2026 application cycle, Emerging Strategies Honorees should have been established in 2021 or later. Organizations that are piloting or exploring emerging ideas are strongly encouraged to apply. Applicants should complete the Emerging Strategies Application Question Form for consideration for this prize.
Funding Type
Internal Deadline
External Deadline
2/17/2026
Solicitation Type

2026 Scientific Infrastructure Support for Consolidated Innovative Nuclear Research (Topic Area 2)

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Limiting Language
The University of Arizona is only eligible to submit to Topic Area 2: General Scientific Infrastructure (GSI)

Topic Area 2: General Scientific Infrastructure (GSI)
An eligible applicant may submit only one application to this topic area. If an entity submits more than
one full application, the DOE will only review the last submission.

Program Purpose 
The Office of Nuclear Energy’s (NE) program purpose is to advance nuclear energy science and technology to meet U.S. energy, environmental and economic needs. NE enables innovation, supports unique research infrastructure, and solves crosscutting challenges facing the nuclear energy sector through research, development and demonstration. NE has identified the following goals to address challenges in the nuclear energy sector, help realize the potential of advanced technology, and leverage the unique role of the government in spurring innovation:

  • Enable continued operation of existing U.S. nuclear reactors.
  • Enable deployment of advanced nuclear reactors.
  • Develop advanced nuclear fuel cycles.
  • Maintain U.S. leadership in nuclear energy technology.

Investing in the next generation of nuclear energy leaders and advancing university-led nuclear
innovation is vital to fulfilling NE's mission, which is primarily accomplished through NE’s Nuclear Energy
University Program (NEUP). NEUP was established in 2009 to consolidate NE’s university support and
enable the integration of university research within NE’s technical programs. Through various
competitive award opportunities, the program engages with U.S. universities and colleges to conduct
research and development (R&D), enhance infrastructure, and support student education, thereby
contributing to the development of a world-class nuclear energy and workforce capability.

Expected Performance Goals:
Topic Area 2: General Scientific Infrastructure (GSI)

  • Procurement of equipment, software, instrumentation, and associated non-reactor upgrade
    requests that support nuclear energy-related R&D or education.
  • Procurement of equipment and instrumentation for specialized facilities, classrooms, and
    teaching laboratories, and non-reactor NS&E research.
  • Procurement of infrastructure that supports the sharing and use of equipment and
    instrumentation by multiple campuses of a university, multiple universities, or with national
    laboratories is encouraged.
Funding Type
Internal Deadline
External Deadline
4/9/2026

Drug-Free Communities Support Program: NEW (Year 1 – FY25 Cohort)

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Limiting Language
Under this NOFO, you may submit only one application under your organization’s Unique Entity Identifier (UEI).

Summary
The purpose of this NOFO is to support community coalitions that work to
prevent and reduce substance use among youth. This NOFO aligns with the
Drug-Free Communities (DFC)’s Support Program’s two goals:
• Establish and strengthen collaboration among community stakeholders
and organizations to address youth substance use.
• Reduce substance use among youth and, over time, reduce substance
use among adults by:
◦ Addressing the factors in a community that increase the risk of
substance use.
◦ Promoting the factors that minimize the risk of substance use.

The DFC program will fund coalitions that haven’t received DFC funding.

Please note: The DFC Program is funded and administered by the White
House Office of National Drug Control Policy (ONDCP). CDC manages the DFC
Program on behalf of ONDCP.
 

Research Category
Funding Type
Internal Deadline
External Deadline
2/12/2026

YouthBuild

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Limiting Language
We will consider only one application from each organization. If an organization submits multiple applications, only the most recently received application that meets the deadline will be considered. If the most recent application is disqualified for any reason, we will not replace it with an earlier application.

Executive Summary
The Employment and Training Administration (ETA), U.S. Department of Labor (DOL, or the Department, or we), announces the availability of grant funds for YouthBuild 2025. Under this Funding Opportunity Announcement (FOA), the DOL will award grants through a competitive process to eligible public or private non-profit organizations or Tribal entities to provide pre-apprenticeship occupational skills training, education, and job placement services to disadvantaged and low-income youth. YouthBuild is a pre-apprenticeship program that prepares participants for quality jobs in various industry sectors and aligns with Executive Order 14278, “Preparing Americans for High-Paying Skilled Trade Jobs of the Future,” specifically by preparing participants to enter and succeed in Registered Apprenticeships. YouthBuild also includes wrap-around supportive services such as assistance in transportation, childcare, and housing. YouthBuild programs must offer participants construction training and hands-on experiences building affordable housing for their community. Programs may also include a Construction Plus component, providing vocational training in additional high-d emand industries.

For further information or technical questions about this FOA, please contact Khanh Tran, Grants Management Specialist, Office of Grants Management, at YB_FOA-ETA-26-38@dol.gov and specifically reference FOA-ETA-26-38. This Announcement is available on the ETA website at https://www.dol.gov/agencies/eta/grants and at https://www.grants.gov.

Research Category
Funding Type
Internal Deadline
External Deadline
3/2/2026
Solicitation Type

OVC FY25 Preventing Trafficking of Girls

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Limiting Language
Applicant may submit only one application under this NOFO. An entity may be proposed as a subrecipient in more than one application. Applications under which two or more entities (project partners) would carry out the federal award will be considered. However, only one entity may be the applicant for the NOFO; any others must be proposed as subrecipients. See the Application Resource Guide for additional information on subawards. 

Executive Summary
This NOFO will develop or enhance prevention and early intervention services for girls who are at risk of, or are victims of, sex and/or labor trafficking. Funding will be provided to programs that replicate and scale up prevention and early intervention programs; and implement or enhance efforts to identify and provide comprehensive services to girls/young women who are at risk of, or are victims of, sex and/or labor trafficking through activities such as street outreach, partnerships with organizations that serve youth, partnerships with juvenile justice and child welfare systems, and/or collaboration with other key community stakeholders. Please see the Eligible Applicants section for the eligibility criteria.  

OJP is committed to advancing work that furthers DOJ’s mission to uphold the rule of law, to keep our country safe, and to protect civil rights. OJP provides federal leadership, funding, and other critical resources to directly support law enforcement, combat violent crime, protect American children, provide services to American crime victims, and address public safety challenges, including human trafficking and the opioid crisis. 

Research Category
Funding Type
Internal Deadline
External Deadline
2/24/2026

OVC FY25 Specialized Human Trafficking Assistance: Supporting Survivor Engagement in AntiTrafficking Programming

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Limiting Language
Applicant may submit only one application under this NOFO. An entity may be proposed as a subrecipient in more than one application. Applications under which two or more entities (project partners) would carry out the federal award will be considered. However, only one entity may be the applicant for the NOFO; any others must be proposed as subrecipients. See the Application Resource Guide for additional information on subawards. 

Purpose of Funding
This NOFO will support sites that are implementing OVC-funded anti-human trafficking programs to design and implement ongoing engagement with survivors of human trafficking, as defined by 22 U.S.C. § 7102(11), to improve outcomes for human trafficking victims.  

To inform and improve anti-trafficking programming, applicants should propose approaches that help build OVC anti-trafficking grantees’ capacity to identify and partner with survivors in their local community, state, or region. The awardee will deliver training and technical assistance on effective victim service programming for trafficking survivors. This includes intensive support to recipients of each fiscal year’s new human trafficking victim service awards during their first year of implementation, as well as ongoing support for entities implementing existing awards.  

OVC expects the successful applicant to propose innovative strategies for OVC anti-trafficking grantees to develop these partnerships and offer organizational peer support on survivor engagement approaches. OVC is interested in proposals that maximize the number of grantees supported through this effort.  

Research Category
Funding Type
Internal Deadline
External Deadline
2/24/2026

ASCENDR Research Grant Program – 2026 Cycle

Institutionally Coordinated // Limit: 2 // Tickets Available: 2

This opportunity is being institutionally coordinated by Research Development Services and the Office of Hispanic Serving Institution Initiatives. If you are interested, please contact Riley McIssac and Cody Nicholls.

Limiting Language
Limit on number of proposals per university: 2

About ASCENDR
ASCENDR Research is a competitively funded DOD research program that is aligned to the U.S. National Defense Science and Technology Strategy and the DOD Critical Technology Areas and part of the HSRU’s Advancing STEM Careers through Education, Networking, Development + Research (ASCENDR) Initiative (for more information about ASCENDR visit www.hsru.org) For this opportunity, research priority areas are: Advanced Materials, Human-Machine Interfaces, and Space Technology. Through this competitively funded research program, HSRU Alliance member institutions’ research strengths will be leveraged, faculty leadership development will be provided, and graduate student researchers will be integrated. This research program will have the aims to (1) expose both faculty and students to military operations and defense and national security real-world challenges, (2) deploy and enhance the research environments conducive for the successful progression and participation of the students in the process (e.g. mentoring, professional development, and financial support), and to (3) conduct research and deliver research outcomes to meet DOD technical challenges/gaps.


 

Funding Type
Internal Deadline
External Deadline
2/27/2026