Translational Bioimaging Resource

TBIR serves as a university-wide resource for pre-clinical biomedical imaging. The resource has the capability to image small biological constructs, small and large animals, and humans. For imaging small biological constructs and small animals the TBIR includes intra-vital microscopy, MRI, ultrasound, CT, PET, SPECT, and bioluminescence. For imaging larger animals and humans the resource includes MRI and ultrasound. The resource includes personnel to help you with project development and to help you use the equipment.

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Machining and Welding Center

We provide prototype machining, designing, fabrication, welding, consultation, instructional support, and community outreach programs. The MWC introduces innovative applications to research and development sectors including faculty, staff, students, and private industry.

Facility Category

Imaging Cores - Optical (Marley & Life Sciences North)

We provide access, training, and ongoing support for users of a wide range of optical (light) microscopes. From stereo and widefield microscopes to more advanced techniques like confocal, multiphoton and superresolution, the facility and the managers are available to provide technical support and consultation to advance scientific inquiry and aid in experimental design.

Facility Category

Imaging Cores - Electron (Life Sciences North)

The core facility is a full service lab providing access to advanced expertise in Biological Transmission Electron Microscopy (TEM) related research, from consultation to imaging service and training to faculty, scientists and students on campus, external research institutions and industrial community.

We receive previously fixed samples, prepare them for TEM, negative staining and immunoelectron microscopy techniques, and perform ultramicrotomy, digital imaging and interpretation of results. Support is also available in planning for future electron microscopy experiments, writing grants, publications, and collaborations.

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Functional Genomics Core (FGC)

The Functional Genomics Core’s mission is to provide researchers at the University of Arizona with the capacity to run high-throughput compound/drug, RNAi, and deletion library based screens for the purpose of network analysis, drug and/or target discovery. We will work with you to develop or optimize an assay, carryout a screen and/or analyze the data. The equipment in the laboratory is also available for general (low-throughput) use.

Analytical & Biological Mass Spectrometry

At the Analytical & Biological Mass Spectrometry Facility (ABMS), we have state-of-the-art equipment and unparalleled expertise for the analysis of a variety of biological and small molecules. One of our specializations includes protein-analysis encompassing: protein identification, protein and peptide sequence confirmation, intact protein molecular weight determination, complex protein sample analysis, and protein/antibody-drug interactions. In addition to proteomics, the ABMS team has developed an in-house metabolomics library (currently containing >700 compounds) to support metabolomic and lipidomics analysis, enabling the interrogation of the underlying metabolomic and lipidomics profiles. Through this proteomics, metabolomics, and lipidomics analysis, a greater in-depth and multi-omics profiling is achieved.


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