Proposal Preparation

Answer this question ‘Yes’ if the proposal involves any of the terms below or involves any biohazardous and/or recombinant materials. For assistance, contact Research Laboratory & Safety Services at (520) 626-6850 or rlss-bio-support@email.arizona.edu(link sends e-mail) or visit the Recombinant and Biohazardous Materials web page.

If the project you are proposing involves the handling or storage of Risk Group 3 biohazardous and/or recombinant materials that would require the use of a BSL-3 laboratory, please contact Research Laboratory & Safety Services at rlss-help@arizona.edu. BSL-3 work must be approved in advance by the Institutional Biosafety Committee (IBC). You can access the documents needed to submit to the committee at  Institutional Biosafety Committee | UArizona Research, Innovation & Impact. Access and training for the BSL-3 spaces is a lengthy process, so reaching out to RLSS early in the process is optimal.

• Adenovirus
• Adenoassociated Virus
• AAV
• Cloning
• Gene therapy
• Genomic library
• Microarray
• Plasmid
• Probes
• Recombinant
• Retrovirus
• Restriction fragment polymorphism (RFLP)
• Sequencing
• Southern / Northern hybridization
• Transformed cells
• Vector
• Bordetella pertussis
• Campylobacter
• Cell Culture
• Coccidiodes
• Chlamydia
• Clostridium
• Coxiella
• Cryptosporidium
• Cyclospora
• Giardia
• herpes
• HIV
• Influenza
• Monkeypox
• Mycobacterium
• Yesinia pestis (plague)
• Salmonella
• Toxin
• Vaccinia
• SARS-CoV-2
• Risk Group 2
• Risk Group 3
• Virus
• Bacteria
• Fungus
• Parasite
• Rickettsia

Answer this question ‘Yes' if the proposal involves handling any human derived products (tissue, saliva, organ, semen, vaginal secretions, feces, urine, blood, cells, etc.), or any other potential infectious materials (PIM) that could carry and transmit bloodborne pathogens. For assistance, contact Research Laboratory & Safety Services at (520) 626-6850 or rlss-bio-support@email.arizona.edu(link sends e-mail) or visit the or visit the Recombinant and Biohazardous Materials web page.

Radiation (Radioactive Material, Sealed Source, Radiation Generating Machine)?

Answer this question “Yes” if this proposal involves the use of Radiation.

Your work will need to be approved by the UA Radiation Safety Committee (RSC) before you can start work.  You can access the documents needed to submit to the committee at https://research.arizona.edu/radiation-safety-forms, “Application for (Radioactive Material/Radiation Machine/Sealed Sources) Approval.”

Training is required before any person can handle Radioactive Material, Radioactive Sealed Sources or Radiation Generating Machines.  Radiation Safety Training can be found on https://edgelearning.arizona.edu/. If you have any questions please reach out to rlss-rad-support@email.arizona.edu.

Non-Ionizing Radiation (Laser)?

Also answer this question “Yes” if this proposal involves the use of any laser or laser product.

Your work will need to be reviewed and approved by the UA Laser Safety Officer (LSO) and Laser Safety Committee (LSC).  You can access the documents needed to submit to the committee at https://research.arizona.edu/compliance/RLSS/radiation-safety/laser-safety-program/laser-approval.

Training is required before any person can operate a laser. Laser training (Laser Radiation Protection Course (LRPC)) can be found on https://edgelearning.arizona.edu/. If you have any questions please reach out to rlss-rad-support@email.arizona.edu.

FDA/EPA Quality Assurance (GLP/cGMP/QA)?

Answer this question ‘Yes’ if the proposal involves any of the terms below or requires adherence to any FDA/EPA quality assurance program. If the project you are proposing involves the manufacture of a medical/therapeutic product, the evaluation of an FDA grant “Test or Control Article”, or collaboration with another researcher/institution upon research requiring FDA/EPA quality assurance program enrollment please contact Research Laboratory & Safety Services at rlss-help@arizona.edu. Visit the Good Laboratory Practices web pages for additional guidance.

At this time, the RLSS maintains a voluntary GLP preparation program (training & inspections), the UArizona has not constituted an institutional Quality Assurance Unit and would need reasonable time to do so to accommodate anyone with an FDA/EPA quality assurance program requirement.

• Good Laboratory Practices
• Good Manufacturing Practices
• Quality Assurance
• 21CFR
• Title 21
• EPA Quality Program
• GLP
• GMP
• cGMP
• Test Article
• Control Article

Answer this question ‘Yes’ if the proposal involves the use and storage (including cleaning and sterilizing of equipment) of any quantity of any solvents, oxidizers, corrosives, compressed gases, cryogenics, heavy metals, dust-generating compounds, ATF regulated materials, DEA Controlled Substances, pesticides, fertilizers, and/or hormones/steroids. Visit the Chemical Safety Program web page for additional guidance or contact Research Laboratory & Safety Services at rlss-help@arizona.edu(link sends e-mail) with questions.

Examples include but are not limited to:

• Ethanol
• Methanol
• Tetrahydrofuran
• Acetone
• Potassium permanganate
• Hydrogen peroxide
• Sodium/Calcium hydroxide
• Sulfuric/Nitric/Acetic acid
• Carbon dioxide
• Argon
• Liquid nitrogen
• Arsenic
• Mercury
• Mine tailings
• Silica powder
• Praxair FE-271 (or other brand additive manufacturing metal powder product)
• Nitrotriazolone (NTO)
• Nitrocellulose
• Ketamine
• Testosterone
• Cannabidiol (CBD)
• Round-Up (or other brand glyphosate product)
• Microthiol (or other brand sulfur fungicide product)
• Pyrethroids
• Novel mode-of-action insecticide
• Urea
• Mono-ammonium phosphate (11-52-0)
• Iron/Zinc/Molybdenum chelates
• Zoetis (or other brand estradiol product)
• Corticosteroids

As a National Cancer Institute Designated Comprehensive Cancer Center Facility, any and all use of the facilities of the Cancer Center must be reported to the National Institutes for Health (NIH) on an annual basis. This includes any use of Cancer Center Facilities, including use of the Common Equipment Rooms and/or the Shared Services of the Cancer Center.  use of any lab, office, common equipment or shared services or any part of the Cancer Center Facility requires approval.

Answer this question ‘Yes’ for any proposal that involves research related to cancer.  This information is compiled for the Arizona Cancer Center annual report.

Answer this question ‘Yes’ if live vertebrate animals are involved in the proposal. A protocol must be submitted for approval to the Institutional Animal Care and Use Committee (IACUC) before an award is made, but not at the time of proposal.

IACUC oversees the university’s animal care and use programs. This unit ensures the humane and ethical treatment of the animals used in research, testing and education.  IACUC reviews all requests to use vertebrate animals to ensure compliance with federal regulations. 

Principal Investigators who plan to use animal subjects as a part of their research should contact a member of the IACUC early in the project design stage to determine appropriate species as models for research and appropriate procedures to be used in the course of research (from UHAP). Visit the Institutional Animal Care and Use Committee (IACUC) program pages of the Research Support website for additional guidance.

Answer this question ‘Yes’ if human subjects are involved in the proposal. The University is required to safeguard human participants that are involved in research projects. For any project involving the use of human participants, a protocol must be submitted to the University’s Human Subject Protection Program (HSPP) and the Institutional Review Board (IRB) for review and approval. 

The HSPP and IRB ensure that Human Subjects rights and welfare are protected, the risk and potential benefits are weighed accurately, subject selection is fair and that the participants have an informed consent.  Approval is required before any work with Human Subjects is initiated.

Visit the Human Subject Protection Program section of the Research Support website for additional guidance.

This question was added to the UAccess Research (UAR) proposal in April 2020 to easily track and report on sponsored project proposals and awards related to COVID-19. Is the project scope of work related to COVID-19?

If you have any questions please contact sponsor@arizona.edu(link sends e-mail).