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NIH-HL-20-814 NOSI (w links to R01 Clinical Trial and Clinical Trial Not Allowed) The Influence of Host Resilience on Heterogeneity of Acute Respiratory Distress Syndrome/Acute Lung Injury

This NOSI seeks to support investigation into the factors and molecular mechanisms that address the heterogeneity dictated by the host resilience. Research on general host responses to injurious challenges and their effects on lung function as well as mechanisms that impact susceptibility to ARDS is not considered to be responsive to this announcement.

This NOSI encourages, but is not limited to, research applications in the following areas:

NIH PAR-20-238 Intervention Research to Improve Native American Health (R01 Clinical Trial Optional)

The purpose of this funding opportunity announcement (FOA) is to support research on interventions to improve health in Native American (NA) populations.

NOT-AI-20-065: Availability of Emergency Awards for Limited Clinical Trials to Evaluate Therapeutic and Vaccine Candidates Against SARS-CoV-2

This Notice of Special Interest encourages cooperative agreement applications for implementation of investigator-initiated high-risk clinical trials, as defined by NIAID in PAR-18-633 and NOT-AI-16-084, that will augment ongoing and planned clinical trials of therapeutic and vaccine candidates directed against SARS-CoV-2 to evaluate:

NOT-MD-20-025: Simulation Modeling and Systems Science to Address Health Disparities

Support investigative and collaborative research focused on developing and evaluating simulation modeling and systems science (SMSS) to understand and address minority health and health disparities. Use SMSS to:
•Foster trans-disciplinary partnerships and collaborations in understanding the etiology and causal pathways of health disparities
•Identify modifiable barriers and cost-effective factors to reduce and eventually eliminate health disparities
•Improve patient safety and reduce medical errors for populations affected by health disparities

Biomedical Advanced Research and Development Authority (BARDA) Broad Agency Announcement (BAA)

Seeks research for an array of medical countermeasures to diagnose, treat, or protect against against COVID-19.

Note: COVID-19 response related Areas of Interest includes:

NOT-GM-20-027: Notice of Special Interest (NOSI): Urgent Competitive Revisions to Accelerate Research on the Development of Predictive Models of the Spread of SARS-CoV-2 and Outcomes of Potential Public Health Interventions on COVID-19

NIGMS will accept applications for Competitive Revisions to active U24 awards for eligible organizations to rapidly provide pilot or supplementary funds to researchers studying the development of predictive models for the spread of SARS-CoV-2 and outcomes of possible COVID-19 public health intervention measures in order to accelerate such research.

Eligible organizations are those with an active NIGMS U24 award responsible for storing, managing, and promoting the shared efforts of a network of researchers studying the modeling of infectious diseases.

NOT-MD-20-019: Notice of Special Interest (NOSI): Competitive and Administrative Supplements for the Impact of COVID-19 Outbreak on Minority Health and Health Disparities

The National Institute on Minority Health and Health Disparities (NIMHD) is issuing this Notice of Special Interest (NOSI) to highlight the urgent need for research on the impact of the novel Coronavirus (SARS-CoV-2) pandemic causing COVID-19 disease outbreaks and the resulting disruptions on individual and social wellbeing, health services use, and health outcomes for NIH-designated health disparity populations.

NOT-MH-20-047: Notice of Special Interest (NOSI) regarding the Availability of Administrative Supplements and Urgent Competitive Revisions for Mental Health Research on the 2019 Novel Coronavirus

NIMH is issuing this Notice of Special Interest (NOSI) to highlight interest in research to strengthen the mental health response to Coronavirus Disease 2019 (COVID-19) caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and to future public health emergencies, including pandemics.

NOT-ES-20-017: NIEHS Worker Training Program Coronavirus and Infectious Disease Response Training (Admin Supp Clinical Trial Not Allowed)

The purpose of this supplement is to provide support for the conduct of worker-based training to prevent and reduce exposure of hospital employees, emergency first responders, and other workers who are at risk of exposure to Coronavirus through their work duties.

NOT-ES-20-015: Notice of Special Interest (NOSI): NIEHS Support for Understanding the Impact of Environmental Exposures on Coronavirus Disease 2019 (COVID-19)

NIEHS is issuing this Notice of Special Interest (NOSI) to address the urgent need for mission-relevant research to understand the impact of environmental exposures on Coronavirus Disease 2019 (COVID-19) and its causative agent, the severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2). NIEHS is particularly interested in applications that will provide insight into the role of environmental exposures in pathogenicity, transmission, individual susceptibility, or prevention and intervention strategies.

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